CiteULike Search Register Log in
CiteULike is a free online bibliography manager. Register and you can start organising your references online.

Recombinant human antibodies specific for hepatitis C virus proteins.

by: G. Esposito, V. Morea, E. Scarselli, A. Cerino, M. U. Mondelli, N. La Monica, C. Traboni
Arch Virol, Vol. 142, No. 3. (1997), pp. 601-610.

X Abstract

Human antibodies to hepatitis C virus core, NS4A and NS3 were cloned in a prokaryotic vector and expressed as soluble Fab fragments and as phage-displayed Fabs. The recombinant Fabs were shown to be a suitable tool for immunohistochemistry, since they recognize the cognate antigen expressed in mammalian cells. The nucleotide sequence of the cDNA for the variable domains of these antibodies was determined and the V-gene usage was derived. On the basis of the deduced amino acid sequence, a structural model of the V domains of the Fabs was constructed.

View the full article here:

Pubmed, Hubmed

This article has been bookmarked 3 times, initially on 2007-01-21.

2007-01-21 User breden
Group FAB-lab
Group SFUAntibodyResearch
Privacy Statement | Terms & Conditions
CiteULike organises scholarly (or academic) papers or literature and provides bibliographic (which means it makes bibliographies) for universities and higher education establishments. It helps undergraduates and postgraduates. People studying for PhDs or in postdoctoral (postdoc) positions. The service is similar in scope to EndNote or RefWorks or any other reference manager like BibTeX, but it is a social bookmarking service for scientists and humanities researchers.