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The common biology of cancer and ageing

by: Toren Finkel, Manuel Serrano, Maria A. Blasco
Nature, Vol. 448, No. 7155. (16 August 2007), pp. 767-774.

X Abstract

At first glance, cancer and ageing would seem to be unlikely bedfellows. Yet the origins for this improbable union can actually be traced back to a sequence of tragic—and some say unethical—events that unfolded more than half a century ago. Here we review the series of key observations that has led to a complex but growing convergence between our understanding of the biology of ageing and the mechanisms that underlie cancer.

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