CiteULike Search Register Log in
CiteULike is a free online bibliography manager. Register and you can start organising your references online.

Caveats of caveolin-1 in cancer progression.

by: E. Burgermeister, M. Liscovitch, C. Röcken, R. M. Schmid, M. P. Ebert
Cancer letters, Vol. 268, No. 2. (18 September 2008), pp. 187-201.

X Abstract

Caveolin-1, an essential scaffold protein of caveolae and cellular transport processes, lately gained recognition as a stage- and tissue-specific tumor modulator in vivo. Patient studies and rodent models corroborated its janus-faced role as a tumor suppressor in non-neoplastic tissue, its down-regulation (loss of function) upon transformation and its re-expression (regain of function) in advanced-stage metastatic and multidrug resistant tumors. This review is focussed on the role of caveolin-1 in metastasis and angiogenesis and its clinical implications as a prognostic marker in cancer progression.

View the full article here:

DOI, Pubmed, Hubmed

This article has been bookmarked once, on 2008-08-26.

2008-08-26 User tsjipko
Privacy Statement | Terms & Conditions
CiteULike organises scholarly (or academic) papers or literature and provides bibliographic (which means it makes bibliographies) for universities and higher education establishments. It helps undergraduates and postgraduates. People studying for PhDs or in postdoctoral (postdoc) positions. The service is similar in scope to EndNote or RefWorks or any other reference manager like BibTeX, but it is a social bookmarking service for scientists and humanities researchers.