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DNA Bending Stiffness on Small Length Scales

by: Chongli Yuan, Huimin Chen, Xiong W. Lou, Lynden A. Archer
Physical Review Letters, Vol. 100, No. 1. (2008), 018102.

X Abstract

Bending properties of short (15–90 bp), double-stranded DNA fragments are quantified using fluorescence resonance energy transfer and small angle x-ray scattering. Results from both types of measurements indicate that short double-stranded DNA fragments exhibit surprisingly high flexibility. These observations are discussed in terms of base-pair-level length fluctuations originating from dynamic features of Watson-Crick base pairs.

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