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TGF-² helps cells fly solo Export

Nature Cell Biology, Vol. 11, No. 11. (18 October 2009), pp. 1281-1284.

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Intravital imaging demonstrates that TGF-² signalling regulates the mode of cancer cell motility. Cells with active TGF-² signalling migrate as single cells and are capable of hematogenous and lymphatic spread, whereas cells lacking TGF-² signalling invade lymphatics collectively.


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