PMUT: a web-based tool for the annotation of pathological mutations on proteins. Export

@article{citeulike:246019, abstract = {PMUT allows the fast and accurate prediction (approximately 80\% success rate in humans) of the pathological character of single point amino acidic mutations based on the use of neural networks. The program also allows the fast scanning of mutational hot spots, which are obtained by three procedures: (1) alanine scanning, (2) massive mutation and (3) genetically accessible mutations. A graphical interface for Protein Data Bank (PDB) structures, when available, and a database containing hot spot profiles for all non-redundant PDB structures are also accessible from the PMUT server.}, author = {Ferrer-Costa, C. and Gelp\'{\i}, J. L. and Zamakola, L. and Parraga, I. and de la Cruz, X. and Orozco, M.}, citeulike-article-id = {246019}, citeulike-linkout-0 = {http://dx.doi.org/10.1093/bioinformatics/bti486}, citeulike-linkout-1 = {http://bioinformatics.oxfordjournals.org/cgi/content/abstract/21/14/3176}, citeulike-linkout-2 = {http://www.ingentaconnect.com/content/oup/cabios/2005/00000021/00000014/art03176}, citeulike-linkout-3 = {http://view.ncbi.nlm.nih.gov/pubmed/15879453}, citeulike-linkout-4 = {http://www.hubmed.org/display.cgi?uids=15879453}, day = {15}, doi = {10.1093/bioinformatics/bti486}, issn = {1367-4803}, journal = {Bioinformatics (Oxford, England) }, keywords = {bioinformatics, comps, function, major-proposal, mutation}, month = {July}, number = {14}, pages = {3176--3178}, posted-at = {2006-09-13 23:26:08}, priority = {0}, publisher = {Oxford University Press}, title = {PMUT: a web-based tool for the annotation of pathological mutations on proteins.}, url = {http://dx.doi.org/10.1093/bioinformatics/bti486}, volume = {21}, year = {2005} }

TY - JOUR ID - citeulike:246019 L3 - citeulike-article-id:246019 N2 - PMUT allows the fast and accurate prediction (approximately 80% success rate in humans) of the pathological character of single point amino acidic mutations based on the use of neural networks. The program also allows the fast scanning of mutational hot spots, which are obtained by three procedures: (1) alanine scanning, (2) massive mutation and (3) genetically accessible mutations. A graphical interface for Protein Data Bank (PDB) structures, when available, and a database containing hot spot profiles for all non-redundant PDB structures are also accessible from the PMUT server. IS - 14 JF - Bioinformatics (Oxford, England) SN - 1367-4803 EP - 3178 TI - PMUT: a web-based tool for the annotation of pathological mutations on proteins. PB - Oxford University Press VL - 21 SP - 3176 KW - bioinformatics KW - comps KW - function KW - major-proposal KW - mutation AU - Ferrer-Costa, C AU - Gelpí, JL AU - Zamakola, L AU - Parraga, I AU - de la Cruz, X AU - Orozco, M PY - 2005/07/15/ UR - http://dx.doi.org/10.1093/bioinformatics/bti486 ER -