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Crystal structure of the entire respiratory complex I

by: Rozbeh Baradaran, John M. Berrisford, Gurdeep S. Minhas, Leonid A. Sazanov
Nature, Vol. 494, No. 7438. (28 February 2013), pp. 443-448, doi:10.1038/nature11871  Key: citeulike:12047921

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Abstract

The atomic-resolution structure of the entire respiratory complex I is reported, with the resolution high enough to map out the locations and orientations of nearly all amino-acid side chainssome of which link to human neurodegenerative diseasesand reveals which amino-acid interactions take place at the hydrophilic domainmembrane domain interface.


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