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Group: LabCompMed - library [443 articles]

Recent papers posted by members of the LabCompMed group
  • Analysis of side-chain rotamers in transmembrane proteins.
    Biophysical journal, Vol. 87, No. 5. (November 2004), pp. 3460-3469.
    by AK Chamberlain, JU Bowie
  • Intracellular retention of mutant gonadotropin receptors results in loss of hormone binding activity of the follitropin receptor but not of the lutropin/choriogonadotropin receptor
    Mol Endocrinol, Vol. 9, No. 12. (1 December 1995), pp. 1727-1736.
    by TG Rozzell, H Wang, X Liu, DL Segaloff
    posted to tmd mutation mol lhr fshr endocr 264 1995 by gcaltabiano to the group LabCompMed on 2008-05-13 16:34:07 as **
  • Crystal structure of squid rhodopsin with intracellularly extended cytoplasmic region.
    The Journal of biological chemistry (6 May 2008)
    by Tatsuro Shimamura, Kenji Hiraki, Naoko Takahashi, Tetsuya Hori, Hideo Ago, Katsuyoshi Masuda, Koji Takio, Masaji Ishiguro, Masashi Miyano
    posted to xray structure rhodopsin gpcr cterm crystallography by xdeupi to the group LabCompMed on 2008-05-13 16:19:24 as **
  • The specificity of binding of glycoprotein hormones to their receptors.
    Cellular and molecular life sciences : CMLS (26 April 2008)
    posted to thyrotropin modeling hormone activation by xdeupi to the group LabCompMed on 2008-05-03 17:06:33 as **
  • notes Transmembrane proteins in the Protein Data Bank: identification and classification.
    Bioinformatics, Vol. 20, No. 17. (22 November 2004), pp. 2964-2972.
    posted to helix membrane_proteins structure by xdeupi to the group LabCompMed on 2008-04-08 13:55:53 as ** along with 3 people viktor21614 chrn sebk
  • Retinylidene proteins: structures and functions from archaea to humans.
    Annual review of cell and developmental biology, Vol. 16 (2000), pp. 365-392.
    by JL Spudich, CS Yang, KH Jung, EN Spudich
    posted to retinal retinal_binding_proteins review rhodopsin structure by xdeupi to the group LabCompMed on 2008-04-08 11:33:18 as **
  • Crystal structure of rhodopsin: implications for vision and beyond.
    Current opinion in structural biology, Vol. 11, No. 4. (August 2001), pp. 420-426.
    posted to retinal retinal_binding_proteins review rhodopsin structure by xdeupi to the group LabCompMed on 2008-04-08 11:29:03 as **
  • Chemogenomic approaches to rational drug design
    Br J Pharmacol, Vol. 152, No. 1. (29 May 2007), pp. 38-52.
    by D Rognan
  • notes Efficient coupling of transducin to monomeric rhodopsin in a phospholipid bilayer.
    J Biol Chem (22 November 2007)
    by Matthew R R Whorton, Beata Jastrzebska, Paul S-H S Park, Dimitrios Fotiadis, Andreas Engel, Krzysztof Palczewski, Roger K K Sunahara
    posted to activation dimer gproteins rhodopsin by xdeupi to the group LabCompMed on 2008-03-12 17:12:36 as ** along with 1 person gcaltabiano
  • How do receptors activate G proteins?
    Adv Protein Chem, Vol. 74 (2007), pp. 67-93.
    by WM Oldham, HE Hamm
    posted to activation gpcr gproteins review rhodopsin by xdeupi to the group LabCompMed on 2008-03-11 14:32:06 as **
  • Heterotrimeric G protein activation by G-protein-coupled receptors.
    Nat Rev Mol Cell Biol (28 November 2007)
    by William M M Oldham, Heidi E E Hamm
  • Chloroethylclonidine and 2-aminoethyl methanethiosulfonate recognize two different conformations of the human alpha(2A)-adrenergic receptor.
    J Biol Chem, Vol. 274, No. 31. (30 July 1999), pp. 21867-21872.
    posted to activation binding cys_scanning drug ligands tm5 by xdeupi to the group LabCompMed on 2008-03-07 15:14:38 as **
  • beta-Arrestin-biased Agonism at the beta2-Adrenergic Receptor.
    J Biol Chem, Vol. 283, No. 9. (29 February 2008), pp. 5669-5676.
    by MT Drake, JD Violin, EJ Whalen, JW Wisler, SK Shenoy, RJ Lefkowitz
  • High-Resolution Crystal Structure of an Engineered Human beta2-Adrenergic G Protein Coupled Receptor.
    Science (25 October 2007)
    by Vadim Cherezov, Daniel M M Rosenbaum, Michael A A Hanson, Søren G F G Rasmussen, Foon Sun S Thian, Tong Sun S Kobilka, Hee-Jung J Choi, Peter Kuhn, William I I Weis, Brian K K Kobilka, Raymond C C Stevens
  • Development of a Quantum Mechanics-Based Free-Energy Perturbation Method: Use in the Calculation of Relative Solvation Free Energies
    J. Am. Chem. Soc., Vol. 126, No. 20. (26 May 2004), pp. 6224-6225.
    by MR Reddy, UC Singh, MD Erion
    posted to fep by gcaltabiano to the group LabCompMed on 2007-09-04 13:25:09 as **
  • Identification of the first germline mutation in the extracellular domain of the follitropin receptor responsible for spontaneous ovarian hyperstimulation syndrome
    Human Mutation, Vol. 9999, No. 9999. (2007), n/a.
    by Anne De Leener, Gianluigi Caltabiano, Sanly Erkan, Mehmet Idil, Gilbert Vassart, Leonardo Pardo, Sabine Costagliola
    posted to tshr tsh sohss mutation mine lh hcg fshr fsh ecd by gcaltabiano to the group LabCompMed on 2007-08-24 10:17:45 as *****
  • G protein-coupled time travel: evolutionary aspects of GPCR research.
    Mol Interv, Vol. 7, No. 1. (February 2007), pp. 17-25.
    posted to review gpcr by gcaltabiano to the group LabCompMed on 2007-08-23 10:30:22 as ** along with 2 people IrinaMoreira superpyrin
  • A New Case of Familial Nonautoimmune Hyperthyroidism Caused by the M463V Mutation in the TSH Receptor with Anticipation of the Disease Across Generations: A Possible Role of Iodine Supplementation.
    Thyroid, Vol. 17, No. 7. (August 2007), pp. 677-680.
    posted to tshr transmembrane mutation by gcaltabiano to the group LabCompMed on 2007-08-23 10:29:09 as **
  • Chemistry. Following the flow of energy in biomolecules.
    Science, Vol. 310, No. 5750. (11 November 2005), pp. 980-982.
    by PM Champion
    posted to rhodopsin review retinal activation by xdeupi to the group LabCompMed on 2007-07-30 17:02:29 as ****
  • Proton movement and photointermediate kinetics in rhodopsin mutants.
    Biochemistry, Vol. 45, No. 17. (2 May 2006), pp. 5430-5439.
    by JW Lewis, I Szundi, MA Kazmi, TP Sakmar, DS Kliger
    posted to rhodopsin protonation activation by xdeupi to the group LabCompMed on 2007-07-30 17:00:28 as **
  • Primary photoprocess in vision: minimal motion to reach the photo- and bathorhodopsin intermediates.
    J Phys Chem B, Vol. 109, No. 18. (12 May 2005), pp. 9104-9110.
    posted to theory rhodopsin retinal activation by xdeupi to the group LabCompMed on 2007-07-30 16:59:24 as **
  • Photoisomerization mechanism of rhodopsin and 9-cis-rhodopsin revealed by x-ray crystallography.
    Biophys J, Vol. 92, No. 12. (15 June 2007)
    by H Nakamichi, V Buss, T Okada
    posted to rhodopsin retinal activation by xdeupi to the group LabCompMed on 2007-07-30 16:57:47 as **
  • Coupling of retinal isomerization to the activation of rhodopsin
    PNAS, Vol. 101, No. 27. (6 July 2004), pp. 10048-10053.
    by Ashish B Patel, Evan Crocker, Markus Eilers, Amiram Hirshfeld, Mordechai Sheves, Steven O Smith
    posted to rhodopsin retinal nmr active-state activation by xdeupi to the group LabCompMed on 2007-07-30 15:16:18 as **
  • The G protein-coupled receptor kinase (GRK) interactome: role of GRKs in GPCR regulation and signaling.
    Biochim Biophys Acta, Vol. 1768, No. 4. (April 2007), pp. 913-922.
    posted to grk gpcr arrestin activation by xdeupi to the group LabCompMed on 2007-07-30 14:59:43 as **
  • A concept for G protein activation by G protein-coupled receptor dimers: the transducin/rhodopsin interface.
    Photochem Photobiol Sci, Vol. 3, No. 6. (June 2004), pp. 628-638.
    posted to structure rhodopsin modeling gproteins active-state by xdeupi to the group LabCompMed on 2007-07-11 16:54:09 as ** along with 1 person cen4ik
  • Refinement of a homology model of the mu-opioid receptor using distance constraints from intrinsic and engineered zinc-binding sites.
    Biochemistry, Vol. 43, No. 27. (13 July 2004), pp. 8700-8710.
    by CB Fowler, ID Pogozheva, H LeVine, HI Mosberg
    posted to theory structure opioid modeling active-state by xdeupi to the group LabCompMed on 2007-07-11 16:51:53 as ** along with 1 person merj
  • Complex of an active mu-opioid receptor with a cyclic peptide agonist modeled from experimental constraints.
    Biochemistry, Vol. 43, No. 50. (21 December 2004), pp. 15796-15810.
    by CB Fowler, ID Pogozheva, AL Lomize, H LeVine, HI Mosberg
    posted to structure opioid modeling gproteins active-state by xdeupi to the group LabCompMed on 2007-07-11 16:50:15 as **
  • Modeling of the complex between transducin and photoactivated rhodopsin, a prototypical G-protein-coupled receptor.
    Biochemistry, Vol. 46, No. 16. (24 April 2007), pp. 4734-4744.
    posted to rhodopsin modeling gproteins by xdeupi to the group LabCompMed on 2007-07-11 11:05:58 as **
  • Formation of Transmembrane Helices In Vivo--Is Hydrophobicity All that Matters?
    J. Gen. Physiol., Vol. 129, No. 5. (30 April 2007), pp. 353-356.
    by Gunnar von Heijne
    posted to transmembrane structure review membrane_proteins helix by xdeupi to the group LabCompMed on 2007-06-29 21:20:58 as ** along with 1 person thaliana
  • Critical role for the second extracellular loop in the binding of both orthosteric and allosteric G protein-coupled receptor ligands.
    J Biol Chem (25 June 2007)
    by Vimesh A A Avlani, Karen J J Gregory, Craig J J Morton, Michael W W Parker, Patrick M M Sexton, Arthur Christopoulos
    posted to structure loops ligands ecl2 binding activation by xdeupi to the group LabCompMed on 2007-06-29 21:12:42 as **
  • G-protein-coupled receptor signalling through protein networks.
    Biochem Soc Trans, Vol. 35, No. Pt 1. (February 2007), pp. 23-27.
    posted to structure review pharmacology gpcr b2ar by xdeupi to the group LabCompMed on 2007-06-29 21:10:57 as **
  • Theoretical study on mutation-induced activation of the luteinizing hormone receptor
    Journal of Molecular Biology, Vol. 296, No. 5. (10 March 2000), pp. 1333-1351.
    by Francesca Fanelli
    posted to transmembrane tmd tm7 signaling mutation mechanism lhr gproteins gpcr by gcaltabiano to the group LabCompMed on 2007-06-26 13:57:21 as **
  • Development and testing of a general amber force field.
    J Comput Chem, Vol. 25, No. 9. (15 July 2004), pp. 1157-1174.
    by J Wang, RM Wolf, JW Caldwell, PA Kollman, DA Case
  • Performance of the general amber force field in modeling aqueous POPC membrane bilayers.
    J Comput Chem, Vol. 28, No. 12. (12 April 2007), pp. 2051-2058.
    by Balázs Jójárt, Tamás A A Martinek
  • Changes in Interhelical Hydrogen Bonding upon Rhodopsin Activation
    Journal of Molecular Biology, Vol. 347, No. 4. (8 April 2005), pp. 803-812.
    by Ashish B Patel, Evan Crocker, Philip J Reeves, Elena V Getmanova, Markus Eilers, Gobind H Khorana, Steven O Smith
    posted to rhodpsin hydrogen helix bond by gcaltabiano to the group LabCompMed on 2007-06-25 16:22:43 as **
  • The Ring of the Rhodopsin Chromophore in a Hydrophobic Activation Switch Within the Binding Pocket
    Journal of Molecular Biology, Vol. 343, No. 3. (22 October 2004), pp. 719-730.
    by Paul J Spooner, Jonathan M Sharples, Scott C Goodall, Petra H Bovee-Geurts, Michiel A Verhoeven, Johan Lugtenburg, Arthur M Pistorius, Willem J Degrip, Anthony Watts
    posted to rhodopsin poket hydrophobic chromophore binding by gcaltabiano to the group LabCompMed on 2007-06-25 12:47:28 as **
  • Effect of different treatments of long-range interactions and sampling conditions in molecular dynamic simulations of rhodopsin embedded in a dipalmitoyl phosphatidylcholine bilayer.
    J Comput Chem (31 January 2007)
    by Arnau Cordomí, Olle Edholm, Juan J J Perez
    posted to theory rhodopsin membrane md dynamics by xdeupi to the group LabCompMed on 2007-06-25 10:30:55 as ** along with 2 people patricia arnaucordomi
  • Heterologous Expression of the Adenosine A1 Receptor in Transgenic Mouse Retina.
    Biochemistry (20 June 2007)
    by Ning Li, David Salom, Li Zhang, Tim Harris, Juan A Ballesteros, Marcin Golczak, Beata Jastrzebska, Krzysztof Palczewski, Carole Kurahara, Todd Juan, Steven Jordan, John A Salon
    posted to pharmacology gpcr expression by xdeupi to the group LabCompMed on 2007-06-25 10:09:54 as **
  • Comparison of stability predictions and simulated unfolding of rhodopsin structures.
    Photochem Photobiol, Vol. 83, No. 2. (r 2007), pp. 351-363.
    posted to transmembrane structure rhodopsin mutation membrane_proteins helix folding by xdeupi to the group LabCompMed on 2007-06-25 10:08:49 as **
  • Refinement of Protein Structures by Iterative Comparative Modeling and CryoEM Density Fitting
    Journal of Molecular Biology, Vol. 357, No. 5. (14 April 2006), pp. 1655-1668.
    by Maya Topf, Matthew L Baker, Marc A Marti-Renom, Wah Chiu, Andrej Sali
    posted to theory structure modeling em crystallography by xdeupi to the group LabCompMed on 2007-06-12 11:28:16 as **
  • The membrane protein universe: what's out there and why bother?
    Journal of Internal Medicine, Vol. 261, No. 6. (June 2007), pp. 543-557.
    by Von Heijne,
    posted to review membrane_proteins by xdeupi to the group LabCompMed on 2007-06-11 10:28:32 as ***** along with 2 people jyuh andreasauerwein
  • Structures and spectral signatures of protonated water networks in bacteriorhodopsin.
    Proc Natl Acad Sci U S A, Vol. 104, No. 17. (24 April 2007), pp. 6980-6985.
    by G Mathias, D Marx
    posted to water theory rhodopsin protonation gpcr activation by xdeupi to the group LabCompMed on 2007-06-11 10:25:44 as *** along with 1 person saravan
  • Mapping allosteric connections from the receptor to the nucleotide-binding pocket of heterotrimeric G proteins.
    Proc Natl Acad Sci U S A (26 April 2007)
    by William M M Oldham, Ned Van Eps, Anita M M Preininger, Wayne L L Hubbell, Heidi E E Hamm
    posted to rhodopsin gproteins cterm activation by xdeupi to the group LabCompMed on 2007-06-11 10:14:49 as ** along with 2 people laurabailey choonpeng
  • Linkage between the intramembrane H-bond network around aspartic acid 83 and the cytosolic environment of helix 8 in photoactivated rhodopsin.
    J Mol Biol, Vol. 366, No. 4. (2 March 2007), pp. 1129-1141.
    by N Lehmann, U Alexiev, K Fahmy
    posted to rhodopsin npxxy fluorescence d250 activation by xdeupi to the group LabCompMed on 2007-06-05 15:58:33 as *****
  • Constitutive activity and inverse agonism at the alpha1adrenoceptors.
    Biochem Pharmacol, Vol. 73, No. 8. (15 April 2007), pp. 1076-1083.
    posted to review gpcr activation by xdeupi to the group LabCompMed on 2007-06-02 19:31:15 as **
  • Real-time analysis of agonist-induced activation of protease-activated receptor 1/Galphai1 protein complex measured by bioluminescence resonance energy transfer in living cells.
    Mol Pharmacol, Vol. 71, No. 5. (May 2007), pp. 1329-1340.
    by MA Ayoub, D Maurel, V Binet, M Fink, L Prézeau, H Ansanay, JP Pin
    posted to fret activation by xdeupi to the group LabCompMed on 2007-06-02 19:29:56 as **
  • Combined solid state and solution NMR studies of alpha,epsilon-15N labeled bovine rhodopsin.
    J Biomol NMR, Vol. 37, No. 4. (April 2007), pp. 303-312.
    posted to structure rhodopsin nmr by xdeupi to the group LabCompMed on 2007-06-02 19:27:51 as ** along with 2 people InesLehner netterpaladin
  • Requirements and ontology for a G protein-coupled receptor oligomerization knowledge base
    BMC Bioinformatics, Vol. 8 (30 May 2007), 177.
    by Lucy Skrabanek, Marta Murcia, Michel Bouvier, Lakshmi Devi, Susan R George, Martin J Lohse, Graeme Milligan, Richard Neubig, Krzysztof Palczewski, Marc Parmentier, Jean-Philippe Pin, Gerrit Vriend, Jonathan A Javitch, Fabien Campagne, Marta Filizola
    posted to review gpcr dimer by xdeupi to the group LabCompMed on 2007-06-02 19:25:57 as **
  • Folding Amphipathic Helices Into Membranes: Amphiphilicity Trumps Hydrophobicity.
    J Mol Biol (22 May 2007)
    by Mónica Fernández-Vidal, Sajith Jayasinghe, Alexey S S Ladokhin, Stephen H H White
    posted to transmembrane membrane_proteins helix folding by xdeupi to the group LabCompMed on 2007-06-02 19:22:34 as **
  • Structure-function of alpha1-adrenergic receptors.
    Biochem Pharmacol, Vol. 73, No. 8. (15 April 2007), pp. 1051-1062.
    by DM Perez
    posted to review gpcr activation by xdeupi to the group LabCompMed on 2007-06-02 19:21:05 as **
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