Group: LabCompMed - with tag b2ar [50 articles] Export Sort

Recent papers posted by members of the LabCompMed group with tag b2ar

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	A specific cholesterol binding site is established by the 2.8 A structure of the human beta2-adrenergic receptor. [My Copy] Structure (London, England : 1993), Vol. 16, No. 6. (June 2008), pp. 897-905. by M. A. Hanson, V. Cherezov, M. T. Griffith, et al.C. B. Roth, V. P. Jaakola, E. Y. Chien, J. Velasquez, P. Kuhn, R. C. Stevens posted to b2ar cholesterol crystallography drug ligands structure by xdeupi to the group LabCompMed on 2009-01-09 12:05:17 as along with 1 person merj
	Structure of a β1-adrenergic G-protein-coupled receptor [My Copy] Nature (25 June 2008) by Tony Warne, Maria J. Serrano-Vega, Jillian G. Baker, et al.Rouslan Moukhametzianov, Patricia C. Edwards, Richard Henderson, Andrew G. W. Leslie, Christopher G. Tate, Gebhard F. X. Schertler posted to b2ar binding docking drug ligands structure xray by xdeupi to the group LabCompMed on 2008-09-16 10:15:18 as along with 2 people and 1 group merj TonyIvetac McCammon
	beta-Arrestin-biased Agonism at the beta2-Adrenergic Receptor. [My Copy] J Biol Chem, Vol. 283, No. 9. (29 February 2008), pp. 5669-5676. by M. T. Drake, J. D. Violin, E. J. Whalen, J. W. Wisler, S. K. Shenoy, R. J. Lefkowitz posted to activation agonist arrestin b2ar biased_agonism drug gproteins imaging internalization ligands pharmacology by xdeupi to the group LabCompMed on 2008-02-27 10:39:07 as
	G-protein-coupled receptor signalling through protein networks. [My Copy] Biochem Soc Trans, Vol. 35, No. Pt 1. (February 2007), pp. 23-27. by A. D. Strosberg, C. Nahmias posted to structure review pharmacology gpcr b2ar by xdeupi to the group LabCompMed on 2007-06-29 21:10:57 as
	G protein coupled receptor structure and activation. [My Copy] Biochim Biophys Acta, Vol. 1768, No. 4. (April 2007), pp. 794-807. by B. K. Kobilka posted to switch review gpcr b2ar activation by xdeupi to the group LabCompMed on 2007-06-02 19:19:32 as along with 4 people and 1 group guhjy Fritz merj adamsdi neurolit
	A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein [My Copy] Proceedings of the National Academy of Sciences, Vol. 104, No. 18. (1 May 2007), pp. 7682-7687. by Matthew R. Whorton, Michael P. Bokoch, SÃ¸ren G. F. Rasmussen, et al.Bo Huang, Richard N. Zare, Brian Kobilka, Roger K. Sunahara posted to dimer b2ar activation by xdeupi to the group LabCompMed on 2007-05-02 09:04:56 as along with 2 people diod stacyfang
	Role of group-conserved residues in the helical core of beta2-adrenergic receptor. [My Copy] Proc Natl Acad Sci U S A, Vol. 104, No. 17. (24 April 2007), pp. 7027-7032. by P. Chelikani, V. Hornak, M. Eilers, et al.P. J. Reeves, S. O. Smith, U. L. Rajbhandary, H. G. Khorana posted to tm4 switch ser b2ar agonist activation by xdeupi to the group LabCompMed on 2007-04-26 12:27:17 as
	Bioluminescence resonance energy transfer as a screening assay: Focus on partial and inverse agonism. [My Copy] J Biomol Screen, Vol. 12, No. 1. (February 2007), pp. 41-49. by L. Elster, C. Elling, A. Heding posted to ligands fret b2ar agonist activation by xdeupi to the group LabCompMed on 2007-04-10 18:50:15 as
	Structure and conformational changes in the C-terminal domain of the beta 2-adrenoceptor: Insights from fluorescence resonance energy tranfer studies. [My Copy] J Biol Chem (8 March 2007) by Sebastien Granier, Samuel Kim, Aaron M M. Shafer, et al.Venkata R P R. Ratnala, Juan J J. Fung, Richard N N. Zare, Brian K K. Kobilka posted to structure fret dynamics cterm b2ar activation by xdeupi to the group LabCompMed on 2007-03-21 11:39:56 as
	Dosage-dependent switch from G protein-coupled to G protein-independent signaling by a GPCR. [My Copy] The EMBO journal, Vol. 26, No. 1. (10 January 2007), pp. 53-64. by Yutong Sun, Jianyun Huang, Yang Xiang, et al.Murat Bastepe, Harald Jüppner, Brian K. Kobilka, Jillian J. Zhang, Xin-Yun Y. Huang posted to switch pharmacology drug b2ar activation by xdeupi to the group LabCompMed on 2007-03-21 11:13:23 as along with 2 people diod Guff32
	Real-time optical recording of beta1-adrenergic receptor activation reveals supersensitivity of the Arg389 variant to carvedilol. [My Copy] The Journal of clinical investigation, Vol. 117, No. 1. (January 2007), pp. 229-235. by Francesca Rochais, Jean-Pierre P. Vilardaga, Viacheslav O. Nikolaev, Moritz Bünemann, Martin J. Lohse, Stefan Engelhardt posted to activation agonist b2ar helix8 mutation by xdeupi to the group LabCompMed on 2007-03-12 14:39:00 as
	Subclassification and nomenclature of alpha- and beta-adrenoceptors. [My Copy] Curr Top Med Chem, Vol. 7, No. 2. (2007), pp. 129-134. by J. P. Hieble posted to agonist b2ar drug genome ligands pharmacology review by xdeupi to the group LabCompMed on 2007-03-12 14:33:19 as
	Recent advances in identification and characterization of beta-adrenoceptor agonists and antagonists. [My Copy] Curr Top Med Chem, Vol. 7, No. 2. (2007), pp. 207-216. by J. P. Hieble posted to agonist b2ar drug ligands pharmacology by xdeupi to the group LabCompMed on 2007-03-12 14:32:04 as
	Organization of beta-adrenoceptor signaling compartments by sympathetic innervation of cardiac myocytes. [My Copy] J Cell Biol, Vol. 176, No. 4. (12 February 2007), pp. 521-533. by O. G. Shcherbakova, C. M. Hurt, Y. Xiang, et al.M. L. Dell'acqua, Q. Zhang, R. W. Tsien, B. K. Kobilka posted to b2ar imaging by xdeupi to the group LabCompMed on 2007-02-20 10:06:46 as
	Both Ligand- and Cell-Specific Parameters Control Ligand Agonism in a Kinetic Model of G Protein-Coupled Receptor Signaling. [My Copy] PLoS Comput Biol, Vol. 3, No. 1. (12 January 2007) by Tamara L L. Kinzer-Ursem, Jennifer J J. Linderman posted to activation agonist b2ar pharmacology by xdeupi to the group LabCompMed on 2007-02-13 15:38:17 as
	The Cationminus signpi Interaction. [My Copy] Chem Rev, Vol. 97, No. 5. (5 August 1997), pp. 1303-1324. by Jennifer C. Ma, Dennis A. Dougherty posted to trp ligands histamine cation-pi binding b2ar by xdeupi to the group LabCompMed on 2007-01-11 14:28:54 as
	Activation of the beta 2-adrenergic receptor involves disruption of an ionic lock between the cytoplasmic ends of transmembrane segments 3 and 6. [My Copy] J Biol Chem, Vol. 276, No. 31. (Aug 2001), pp. 29171-29177. by J. A. Ballesteros, A. D. Jensen, G. Liapakis, et al.S. G. Rasmussen, L. Shi, U. Gether, J. A. Javitch posted to b2ar bibtex-nicole gpcr ionic lock tm3 tm6 by ndoelker to the group LabCompMed on 2006-10-30 16:53:04 as
	Beta2 adrenergic receptor activation. Modulation of the proline kink in transmembrane 6 by a rotamer toggle switch. [My Copy] J Biol Chem, Vol. 277, No. 43. (Oct 2002), pp. 40989-40996. by Lei Shi, George Liapakis, Rui Xu, Frank Guarnieri, Juan A. Ballesteros, Jonathan A. Javitch posted to b2ar bibtex-nicole gpcr pro-kink switch tm6 toggle by ndoelker to the group LabCompMed on 2006-10-30 16:52:55 as
	dummy [My Copy] by Dummy posted to 5ht1a activation agonist amber amine arrestin b2ar bimane binding cam ccr5 channel chemokine chimera crystallography cterm cxcr1 d250 dimer disease drug dry dynamics ecl2 evolution expression fluorescence folding fret genome gly gpcr gproteins hbond helix helix8 histamine hormone icl3 imaging internalization ionic leukotriene lhr ligands lipids lock loops md membrane modeling mutation n745 n749 nmr npxxy nterm opioid pharmacology polymorphism pro-kink protonation review rhodopsin s542 sequence ser spin_labeling structure switch test thr thyrotropin tm2 tm3 tm5 tm6 tm7 toggle transmembrane trp txp w648 by xdeupi to the group LabCompMed on 2006-10-30 12:30:16 as along with 2 people jessicaopacic ivanrt
	Modeling and active site refinement for G protein-coupled receptors: application to the beta-2 adrenergic receptor. [My Copy] J Comput Aided Mol Des (13 October 2006) by Stanley R. Krystek, S R. Kimura, Andrew J. Tebben posted to b2ar binding drug ligands modeling pharmacology by xdeupi to the group LabCompMed on 2006-10-27 09:43:03 as along with 1 person daevans
	GRK specificity for beta -arrestin recruitment to the beta 2-adrenergic receptor revealed by fluorescence resonance energy transfer. [My Copy] J Biol Chem (10 May 2006) by Jonathan D D. Violin, Xiu-Rong R. Ren, Robert J J. Lefkowitz posted to arrestin b2ar fret gpcr by xdeupi to the group LabCompMed on 2006-09-23 11:20:25 as along with 1 person tkershaw
	Functional selectivity and classical concepts of quantitative pharmacology. [My Copy] J Pharmacol Exp Ther (27 June 2006) by Jonathan D D. Urban, William P P. Clarke, Mark von Zastrow, et al.David E E. Nichols, Brian K K. Kobilka, Harel Weinstein, Jonathan A A. Javitch, Bryan L L. Roth, Arthur Christopoulos, Patrick Sexton, Keith Miller, Michael Spedding, Richard B B. Mailman posted to activation b2ar pharmacology review switch by xdeupi to the group LabCompMed on 2006-09-07 15:43:50 as along with 2 people shoshin kentsis
	Coupling ligand structure to specific conformational switches in the [beta]2-adrenoceptor [My Copy] Nat Chem Biol, Vol. 2, No. 8. (2006), pp. 417-422. by Xiaojie Yao, Charles Parnot, Xavier Deupi, et al.Venkata R. Ratnala, Gayathri Swaminath, David Farrens, Brian Kobilka posted to activation b2ar bimane lock by xdeupi to the group LabCompMed on 2006-09-07 14:39:58 as along with 1 person lechristophe
	A polymorphism within a conserved beta(1)-adrenergic receptor motif alters cardiac function and beta-blocker response in human heart failure. [My Copy] Proc Natl Acad Sci U S A, Vol. 103, No. 30. (25 July 2006), pp. 11288-11293. by S. B. Liggett, J. Mialet-Perez, S. Thaneemit-Chen, et al.S. A. Weber, S. M. Greene, D. Hodne, B. Nelson, J. Morrison, M. J. Domanski, L. E. Wagoner, W. T. Abraham, J. L. Anderson, J. F. Carlquist, H. J. Krause-Steinrauf, L. C. Lazzeroni, J. D. Port, P. W. Lavori, M. R. Bristow posted to b2ar disease drug genome helix8 ligands polymorphism by xdeupi to the group LabCompMed on 2006-09-05 11:38:25 as
	Novel mutants of the human beta1-adrenergic receptor reveal amino acids relevant for receptor activation. [My Copy] J Biol Chem, Vol. 281, No. 26. (30 June 2006), pp. 18120-18125. by B. Behr, C. Hoffmann, G. Ottolina, K. N. Klotz posted to activation agonist b2ar binding drug ligands modeling mutation pharmacology structure by xdeupi to the group LabCompMed on 2006-09-05 11:05:20 as
	The three-dimensional structure of the N-terminal domain of corticotropin-releasing factor receptors: sushi domains and the B1 family of G protein-coupled receptors. [My Copy] Ann N Y Acad Sci, Vol. 1070 (July 2006), pp. 105-119. by M. H. Perrin, C. R. Grace, R. Riek, W. W. Vale posted to b2ar nterm structure by xdeupi to the group LabCompMed on 2006-09-05 10:22:30 as
	Metal Ion Site Engineering Indicates a Global Toggle Switch Model for Seven-transmembrane Receptor Activation. [My Copy] J Biol Chem, Vol. 281, No. 25. (23 June 2006), pp. 17337-17346. by C. E. Elling, T. M. Frimurer, L. O. Gerlach, R. Jorgensen, B. Holst, T. W. Schwartz posted to activation b2ar modeling pro-kink structure switch toggle transmembrane by xdeupi to the group LabCompMed on 2006-07-04 12:17:13 as along with 1 person IrinaMoreira
	Changes in interhelical hydrogen bonding upon rhodopsin activation. [My Copy] J Mol Biol, Vol. 347, No. 4. (8 April 2005), pp. 803-812. by A. B. Patel, E. Crocker, P. J. Reeves, et al.E. V. Getmanova, M. Eilers, H. G. Khorana, S. O. Smith posted to activation b2ar binding hbond helix ligands nmr pro-kink rhodopsin ser structure switch tm5 tm6 toggle by xdeupi to the group LabCompMed on 2006-06-01 13:51:11 as
	Toward the active conformations of rhodopsin and the beta2-adrenergic receptor. [My Copy] Proteins, Vol. 56, No. 1. (1 July 2004), pp. 67-84. by P. R. Gouldson, N. J. Kidley, R. P. Bywater, et al.G. Psaroudakis, H. D. Brooks, C. Diaz, D. Shire, C. A. Reynolds posted to activation b2ar modeling rhodopsin structure by xdeupi to the group LabCompMed on 2006-03-08 14:57:08 as
	Molecular evolution of adrenoceptors and dopamine receptors: implications for the binding of catecholamines. [My Copy] J Med Chem, Vol. 49, No. 5. (9 March 2006), pp. 1706-1719. by H. Xhaard, V. V. Rantanen, T. Nyrönen, M. S. Johnson posted to agonist b2ar binding gpcr ligands modeling by xdeupi to the group LabCompMed on 2006-03-06 10:11:30 as
	Molecular mechanisms of beta2-adrenergic receptor function and regulation. [My Copy] Proc Am Thorac Soc, Vol. 2, No. 4. (2005) by D. W. McGraw, S. B. Liggett posted to activation agonist b2ar by xdeupi to the group LabCompMed on 2006-02-20 09:27:39 as
	Imaging nanometer domains of beta-adrenergic receptor complexes on the surface of cardiac myocytes. [My Copy] Nat Chem Biol, Vol. 1, No. 4. (September 2005), pp. 196-202. by A. Ianoul, D. D. Grant, Y. Rouleau, M. Bani-Yaghoub, L. J. Johnston, J. P. Pezacki posted to b2ar fluorescence imaging by xdeupi to the group LabCompMed on 2006-02-13 15:59:57 as
	Functional domains of the mouse beta3-adrenoceptor associated with differential G protein coupling. [My Copy] J Pharmacol Exp Ther, Vol. 315, No. 3. (December 2005), pp. 1354-1361. by M. Sato, D. S. Hutchinson, T. Bengtsson, et al.A. Floren, U. Langel, T. Horinouchi, B. A. Evans, R. J. Summers posted to activation b2ar gproteins by xdeupi to the group LabCompMed on 2006-01-30 09:22:20 as
	beta-Arrestin-dependent, G Protein-independent ERK1/2 Activation by the beta2 Adrenergic Receptor [My Copy] J. Biol. Chem., Vol. 281, No. 2. (13 January 2006), pp. 1261-1273. by Sudha K. Shenoy, Matthew T. Drake, Christopher D. Nelson, et al.Daniel A. Houtz, Kunhong Xiao, Srinivasan Madabushi, Eric Reiter, Richard T. Premont, Olivier Lichtarge, Robert J. Lefkowitz posted to activation arrestin b2ar by xdeupi to the group LabCompMed on 2006-01-11 11:33:08 as
	Beta2-adrenoceptor gene polymorphisms. [My Copy] Pharmacogenet Genomics, Vol. 15, No. 5. (May 2005), pp. 267-275. by O. E. Brodde, K. Leineweber posted to b2ar polymorphism by xdeupi to the group LabCompMed on 2006-01-11 11:26:48 as
	Functionally different agonists induce distinct conformations in the G protein coupling domain of the beta 2 adrenergic receptor. [My Copy] J Biol Chem, Vol. 276, No. 27. (6 July 2001), pp. 24433-24436. by P. Ghanouni, Z. Gryczynski, J. J. Steenhuis, et al.T. W. Lee, D. L. Farrens, J. R. Lakowicz, B. K. Kobilka posted to activation agonist b2ar by xdeupi to the group LabCompMed on 2005-12-16 10:23:33 as
	Agonist-induced conformational changes in the G-protein-coupling domain of the beta 2 adrenergic receptor. [My Copy] Proc Natl Acad Sci U S A, Vol. 98, No. 11. (22 May 2001), pp. 5997-6002. by P. Ghanouni, J. J. Steenhuis, D. L. Farrens, B. K. Kobilka posted to activation agonist b2ar fluorescence by xdeupi to the group LabCompMed on 2005-12-16 10:22:41 as
	Single-molecule spectroscopy of the beta(2) adrenergic receptor: observation of conformational substates in a membrane protein. [My Copy] Proc Natl Acad Sci U S A, Vol. 98, No. 15. (17 July 2001), pp. 8469-8474. by G. Peleg, P. Ghanouni, B. K. Kobilka, R. N. Zare posted to activation agonist b2ar by xdeupi to the group LabCompMed on 2005-12-16 10:21:35 as along with 2 people and 1 group quanwang yanjiang moernerlab
	Sequential binding of agonists to the beta2 adrenoceptor. Kinetic evidence for intermediate conformational states. [My Copy] J Biol Chem, Vol. 279, No. 1. (2 January 2004), pp. 686-691. by G. Swaminath, Y. Xiang, T. W. Lee, J. Steenhuis, C. Parnot, B. K. Kobilka posted to activation agonist b2ar binding ligands tm6 by xdeupi to the group LabCompMed on 2005-12-16 10:19:18 as along with 1 person jddowney
	Mechanisms of disease: beta-adrenergic receptors--alterations in signal transduction and pharmacogenomics in heart failure. [My Copy] Nat Clin Pract Cardiovasc Med, Vol. 2, No. 9. (September 2005), pp. 475-483. by D. S. Feldman, C. A. Carnes, W. T. Abraham, M. R. Bristow posted to b2ar disease by xdeupi to the group LabCompMed on 2005-11-04 22:01:30 as
	Agonist binding: a multistep process. [My Copy] Mol Pharmacol, Vol. 65, No. 5. (May 2004), pp. 1060-1062. by B. Kobilka posted to activation agonist b2ar binding gpcr by xdeupi to the group LabCompMed on 2005-11-02 22:50:37 as
	The forgotten serine. A critical role for Ser-2035.42 in ligand binding to and activation of the beta 2-adrenergic receptor. [My Copy] J Biol Chem, Vol. 275, No. 48. (1 December 2000), pp. 37779-37788. by G. Liapakis, J. A. Ballesteros, S. Papachristou, W. C. Chan, X. Chen, J. A. Javitch posted to activation agonist b2ar binding s542 ser tm5 by xdeupi to the group LabCompMed on 2005-11-01 01:02:07 as
	Activation of the beta 2-adrenergic receptor involves disruption of an ionic lock between the cytoplasmic ends of transmembrane segments 3 and 6. [My Copy] The Journal of biological chemistry, Vol. 276, No. 31. (3 August 2001), pp. 29171-29177. by J. A. Ballesteros, A. D. Jensen, G. Liapakis, et al.S. G. Rasmussen, L. Shi, U. Gether, J. A. Javitch posted to activation b2ar gpcr helix ionic lock pro-kink switch tm3 tm6 by xdeupi to the group LabCompMed on 2005-11-01 00:58:31 as along with 1 person IrinaMoreira
	Synergistic contributions of the functional groups of epinephrine to its affinity and efficacy at the beta2 adrenergic receptor. [My Copy] Mol Pharmacol, Vol. 65, No. 5. (May 2004), pp. 1181-1190. by G. Liapakis, W. C. Chan, M. Papadokostaki, J. A. Javitch posted to activation agonist b2ar by xdeupi to the group LabCompMed on 2005-11-01 00:57:14 as
	Catechol-binding serines of beta(2)-adrenergic receptors control the equilibrium between active and inactive receptor states. [My Copy] Mol Pharmacol, Vol. 57, No. 1. (January 2000), pp. 198-210. by C. Ambrosio, P. Molinari, S. Cotecchia, T. Costa posted to activation agonist b2ar ser tm5 by xdeupi to the group LabCompMed on 2005-10-31 23:56:50 as
	Mutations inducing divergent shifts of constitutive activity reveal different modes of binding among catecholamine analogues to the beta(2)-adrenergic receptor. [My Copy] Br J Pharmacol, Vol. 135, No. 7. (April 2002), pp. 1715-1722. by R. Del Carmine, C. Ambrosio, M. Sbraccia, S. Cotecchia, A. P. Ijzerman, T. Costa posted to activation agonist b2ar by xdeupi to the group LabCompMed on 2005-10-31 23:55:27 as
	"Induced-fit" mechanism for catecholamine binding to the beta2-adrenergic receptor. [My Copy] Mol Pharmacol, Vol. 66, No. 2. (August 2004), pp. 356-363. by R. Del Carmine, P. Molinari, M. Sbraccia, C. Ambrosio, T. Costa posted to activation agonist b2ar by xdeupi to the group LabCompMed on 2005-10-31 23:54:36 as
	Different structural requirements for the constitutive and the agonist-induced activities of the beta2-adrenergic receptor. [My Copy] J Biol Chem, Vol. 280, No. 25. (24 June 2005), pp. 23464-23474. by C. Ambrosio, P. Molinari, F. Fanelli, et al.Y. Chuman, M. Sbraccia, O. Ugur, T. Costa posted to activation agonist b2ar ser by xdeupi to the group LabCompMed on 2005-10-31 23:54:01 as
	Beta2 adrenergic receptor activation. Modulation of the proline kink in transmembrane 6 by a rotamer toggle switch. [My Copy] J Biol Chem, Vol. 277, No. 43. (25 October 2002), pp. 40989-40996. by L. Shi, G. Liapakis, R. Xu, F. Guarnieri, J. A. Ballesteros, J. A. Javitch posted to activation b2ar pro-kink switch tm6 toggle w648 by xdeupi to the group LabCompMed on 2005-10-28 05:04:25 as along with 1 person IrinaMoreira
	Probing the beta2 adrenoceptor binding site with catechol reveals differences in binding and activation by agonists and partial agonists. [My Copy] J Biol Chem, Vol. 280, No. 23. (10 June 2005), pp. 22165-22171. by G. Swaminath, X. Deupi, T. W. Lee, et al.W. Zhu, F. S. Thian, T. S. Kobilka, B. Kobilka posted to activation agonist b2ar switch toggle by xdeupi to the group LabCompMed on 2005-10-25 01:25:28 as along with 1 person and 2 groups marcius BioinfoCIPF SGU-CIPF

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