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Efficient comparison of sets of intervals with NC-lists

by: Matthias Zytnicki, YuFei Luo, Hadi Quesneville
Bioinformatics, Vol. 29, No. 7. (01 April 2013), pp. 933-939, doi:10.1093/bioinformatics/btt070  Key: citeulike:12033955

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Abstract

Motivation: High-throughput sequencing produces in a small amount of time a large amount of data, which are usually difficult to analyze. Mapping the reads to the transcripts they originate from, to quantify the expression of the genes, is a simple, yet time demanding, example of analysis. Fast genomic comparison algorithms are thus crucial for the analysis of the ever-expanding number of reads sequenced.


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