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In 2003, Dr. Elias Zerhouni created the National Institutes of Health (NIH) roadmap and articulated an agenda to aggressively pursue a more integrated approach to use research discoveries to impact human health. Working groups focused on three major themes: New Pathways to Discovery, Research Teams of the Future, and Reengineering the Clinical Research Enterprise. The findings illustrated the need to develop science to decipher biological networks, and the need for broad-scale application of bioinformatics and computational methods to biological systems [1]. In March 2007, the Department of Health and Human Services launched the Personalized Health Care Initiative (PHCI) with the aim to accelerate the development of personalized treatment strategies. The program focuses on high-throughput technologies and developing an infrastructure to promote electronic medical records [2].
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