Development of pro- and antisaccades in children with attention-deficit hyperactivity disorder (ADHD) and healthy controls. Export

@article{citeulike:2914609, abstract = {To date, the investigation of the antisaccade task, a simple test of "executive functions," in children with ADHD has yielded inconsistent results. The present study aimed at contributing to this issue by (a) the investigation of a large sample of carefully diagnosed ADHD patients aged 7-15 years, and (b) the analyses of differential age effects in patients and controls. Healthy control children were pairwise matched with patients (N = 46; age = 136 +/- 24 months) for age and gender, and did not significantly differ in IQ. Horizontal pro- and antisaccades were elicited under the 200-ms gap and overlap conditions (blocks of 100 trials each). Overall, patients exhibited (a) augmented pro- and antisaccadic reaction times, (b) augmented error rates (antitasks), (c) augmented proportions of early responses (all conditions), and (d) reduced proportions of express saccades under the prosaccadic gap condition. The greater decline in anti- as compared to pro-SRT with increasing age that characterized controls was missing in patients. Confirming Barkley's (1997) neuropsychological theory of ADHD, these results altogether point to alterations in "executive functions" in ADHD patients that are presumably supported by frontal lobe structures, in particular the lateral prefrontal cortex and the frontal eye fields.}, address = {Department of Psychology, Research Group Psychophysiology, University of Freiburg, Freiburg, Germany. klein@psychologie.uni-freiburg.de}, author = {Klein, C. H. and Raschke, A. and Brandenbusch, A.}, citeulike-article-id = {2914609}, citeulike-linkout-0 = {http://view.ncbi.nlm.nih.gov/pubmed/12756978}, citeulike-linkout-1 = {http://www.hubmed.org/display.cgi?uids=12756978}, issn = {0048-5772}, journal = {Psychophysiology}, keywords = {adhd, antisaccade, child, express\_saccade, saccade}, month = {January}, number = {1}, pages = {17--28}, posted-at = {2008-06-22 05:57:16}, priority = {2}, title = {Development of pro- and antisaccades in children with attention-deficit hyperactivity disorder (ADHD) and healthy controls.}, url = {http://view.ncbi.nlm.nih.gov/pubmed/12756978}, volume = {40}, year = {2003} }

TY - JOUR ID - citeulike:2914609 L3 - citeulike-article-id:2914609 N2 - To date, the investigation of the antisaccade task, a simple test of "executive functions," in children with ADHD has yielded inconsistent results. The present study aimed at contributing to this issue by (a) the investigation of a large sample of carefully diagnosed ADHD patients aged 7-15 years, and (b) the analyses of differential age effects in patients and controls. Healthy control children were pairwise matched with patients (N = 46; age = 136 +/- 24 months) for age and gender, and did not significantly differ in IQ. Horizontal pro- and antisaccades were elicited under the 200-ms gap and overlap conditions (blocks of 100 trials each). Overall, patients exhibited (a) augmented pro- and antisaccadic reaction times, (b) augmented error rates (antitasks), (c) augmented proportions of early responses (all conditions), and (d) reduced proportions of express saccades under the prosaccadic gap condition. The greater decline in anti- as compared to pro-SRT with increasing age that characterized controls was missing in patients. Confirming Barkley's (1997) neuropsychological theory of ADHD, these results altogether point to alterations in "executive functions" in ADHD patients that are presumably supported by frontal lobe structures, in particular the lateral prefrontal cortex and the frontal eye fields. IS - 1 JF - Psychophysiology SN - 0048-5772 AD - Department of Psychology, Research Group Psychophysiology, University of Freiburg, Freiburg, Germany. klein@psychologie.uni-freiburg.de EP - 28 TI - Development of pro- and antisaccades in children with attention-deficit hyperactivity disorder (ADHD) and healthy controls. VL - 40 SP - 17 KW - adhd KW - antisaccade KW - child KW - express_saccade KW - saccade AU - Klein, CH AU - Raschke, A AU - Brandenbusch, A PY - 2003/01// UR - http://view.ncbi.nlm.nih.gov/pubmed/12756978 ER -