Functional Brain Networks Develop from a “Local to Distributed” Organization Export

@article{citeulike:4483728, abstract = {<title>Author Summary</title> <p>The first two decades of life represent a period of extraordinary developmental change in sensory, motor, and cognitive abilities. One of the ultimate goals of developmental cognitive neuroscience is to link the complex behavioral milestones that occur throughout this time period with the equally intricate functional and structural changes of the underlying neural substrate. Achieving this goal would not only give us a deeper understanding of normal development but also a richer insight into the nature of developmental disorders. In this report, we use computational analyses, in combination with a recently developed MRI technique that measures spontaneous brain activity, to help us to understand the principles that guide the maturation of the human brain. We find that brain regions in children communicate with other regions more locally but that over age communication becomes more distributed. Interestingly, the efficiency of communication in children (measured as a 'small world' network) is comparable to that of the adult. We argue that these findings have important implications for understanding both the maturation and the function of neural systems in typical and atypical development.</p>}, author = {Fair, Damien A. and Cohen, Alexander L. and Power, Jonathan D. and Dosenbach, Nico U. F. and Church, Jessica A. and Miezin, Francis M. and Schlaggar, Bradley L. and Petersen, Steven E.}, citeulike-article-id = {4483728}, citeulike-linkout-0 = {http://dx.doi.org/10.1371/journal.pcbi.1000381}, citeulike-linkout-1 = {http://view.ncbi.nlm.nih.gov/pubmed/19412534}, citeulike-linkout-2 = {http://www.hubmed.org/display.cgi?uids=19412534}, doi = {10.1371/journal.pcbi.1000381}, journal = {PLoS Comput Biol}, keywords = {development, fmri, networks, resting-state}, month = {May}, number = {5}, pages = {e1000381+}, posted-at = {2009-05-11 21:21:21}, priority = {5}, publisher = {Public Library of Science}, title = {Functional Brain Networks Develop from a ” Local to Distributed” Organization}, url = {http://dx.doi.org/10.1371/journal.pcbi.1000381}, volume = {5}, year = {2009} }

TY - JOUR ID - citeulike:4483728 L3 - citeulike-article-id:4483728 N2 - <title>Author Summary</title> <p>The first two decades of life represent a period of extraordinary developmental change in sensory, motor, and cognitive abilities. One of the ultimate goals of developmental cognitive neuroscience is to link the complex behavioral milestones that occur throughout this time period with the equally intricate functional and structural changes of the underlying neural substrate. Achieving this goal would not only give us a deeper understanding of normal development but also a richer insight into the nature of developmental disorders. In this report, we use computational analyses, in combination with a recently developed MRI technique that measures spontaneous brain activity, to help us to understand the principles that guide the maturation of the human brain. We find that brain regions in children communicate with other regions more locally but that over age communication becomes more distributed. Interestingly, the efficiency of communication in children (measured as a ‘small world’ network) is comparable to that of the adult. We argue that these findings have important implications for understanding both the maturation and the function of neural systems in typical and atypical development.</p> IS - 5 JF - PLoS Comput Biol TI - Functional Brain Networks Develop from a “Local to Distributed” Organization PB - Public Library of Science VL - 5 SP - e1000381 KW - development KW - fmri KW - networks KW - resting-state AU - Fair, Damien AU - Cohen, Alexander AU - Power, Jonathan AU - Dosenbach, Nico AU - Church, Jessica AU - Miezin, Francis AU - Schlaggar, Bradley AU - Petersen, Steven PY - 2009/05/01/ UR - http://dx.doi.org/10.1371/journal.pcbi.1000381 ER -