How well are protein structures annotated in secondary databases? Export

@article{citeulike:311792, abstract = {We investigated to what extent Protein Data Bank (PDB) entries are annotated with second-party information based on existing cross-references between PDB and 15 other databases. We report 2 interesting findings. First, there is a clear "annotation gap" for structures less than 7 years old for secondary databases that are manually curated. Second, the examined databases overlap with each other quite well, dividing the PDB into 2 well-annotated thirds and one poorly annotated third. Both observations should be taken into account in any study depending on the selection of protein structures by their annotation.}, address = {Berlin Center of Genome-Based Bioinformatics (BCB), Institute of Biochemistry at the Charit\'{e}, Humboldt Universit\"{a}t Berlin, Berlin, Germany. kristian.rother@charite.de}, author = {Rother, K. and Michalsky, E. and Leser, U.}, citeulike-article-id = {311792}, citeulike-linkout-0 = {http://dx.doi.org/10.1002/prot.20520}, citeulike-linkout-1 = {http://view.ncbi.nlm.nih.gov/pubmed/16021624}, citeulike-linkout-2 = {http://www.hubmed.org/display.cgi?uids=16021624}, day = {1}, doi = {10.1002/prot.20520}, issn = {1097-0134}, journal = {Proteins}, keywords = {databases, protein, structure}, month = {September}, number = {4}, pages = {571--576}, posted-at = {2005-09-06 06:54:34}, priority = {2}, title = {How well are protein structures annotated in secondary databases?}, url = {http://dx.doi.org/10.1002/prot.20520}, volume = {60}, year = {2005} }

TY - JOUR ID - citeulike:311792 L3 - citeulike-article-id:311792 N2 - We investigated to what extent Protein Data Bank (PDB) entries are annotated with second-party information based on existing cross-references between PDB and 15 other databases. We report 2 interesting findings. First, there is a clear "annotation gap" for structures less than 7 years old for secondary databases that are manually curated. Second, the examined databases overlap with each other quite well, dividing the PDB into 2 well-annotated thirds and one poorly annotated third. Both observations should be taken into account in any study depending on the selection of protein structures by their annotation. IS - 4 JF - Proteins SN - 1097-0134 AD - Berlin Center of Genome-Based Bioinformatics (BCB), Institute of Biochemistry at the Charité, Humboldt Universität Berlin, Berlin, Germany. kristian.rother@charite.de EP - 576 TI - How well are protein structures annotated in secondary databases? VL - 60 SP - 571 KW - databases KW - protein KW - structure AU - Rother, K AU - Michalsky, E AU - Leser, U PY - 2005/09/01/ UR - http://dx.doi.org/10.1002/prot.20520 ER -