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Group: Fetal_Pain - with tag opiates [5 articles]

Recent papers posted by members of the Fetal_Pain group with tag opiates

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	The effect of continuous morphine administration on maternal plasma oxytocin concentration and uterine contractions after open fetal surgery. J Matern Fetal Neonatal Med, Vol. 19, No. 4. (April 2006), pp. 231-238. by J. Santolaya-Forgas, R. Romero, R. Mehendale posted to analgesia labour opiates oxytocin preterm primate by fdbuck0 to the group Fetal_Pain on 2006-09-19 14:07:25 Abstract Copy My Attachments My Copy Abstract OBJECTIVE: A major complication of open fetal surgery is prematurity. We propose that fetal and maternal stress/pain after surgery may affect the concentration of circulating oxytocin and the frequency of uterine contractions, thus increasing the risk of preterm delivery. The objective of this study was to test whether continuous morphine sulfate administration after open fetal surgery has an effect on maternal plasma oxytocin concentration and the frequency of uterine contractions. METHODS: An established time-pregnant primate model for open fetal surgery was ...
	Placental transfer and neonatal effects of epidural sufentanil and fentanyl administered with bupivacaine during labor. Anesthesiology, Vol. 83, No. 2. (August 1995), pp. 300-308. by J. R. Loftus, H. Hill, S. E. Cohen posted to human opiates placentaltransfer by fdbuck0 to the group Fetal_Pain on 2006-09-19 13:57:30 Abstract Copy My Attachments My Copy Abstract BACKGROUND: This randomized double-blind investigation was designed to study the placental transfer and neonatal effects of epidural sufentanil and fentanyl infused with bupivacaine for labor analgesia. METHODS: Healthy parturient women (n = 36) received epidural bupivacaine alone (group B) or with fentanyl (group B-F) or sufentanil (group B-S). Group B received a 12-ml bolus of 0.25% bupivacaine followed by a 10 ml/h infusion of 0.125% bupivacaine. Groups B-F and B-S received a 12-ml bolus of 0.125% bupivacaine with 75 micrograms fentanyl ...
	Epidural opioid analgesia in infant rats II: responses to carrageenan and capsaicin. Pain, Vol. 82, No. 1. (July 1999), pp. 33-38. by D. Marsh, A. Dickenson, D. Hatch, M. Fitzgerald posted to analgesia neonatal opiates pain rat by fdbuck0 to the group Fetal_Pain on 2005-12-22 16:05:49 Abstract Copy My Attachments My Copy Abstract The aim of this study was to investigate the analgesic effects of epidural opioids upon persistent pain sensitivity in neonatal rat pups. Two models of persistent pain were used, subcutaneous injection of carrageenan, and topical application of capsaicin cream, both to the hind paw. The contribution of individual opioid receptor subtypes in the spinal cord to analgesia were tested at different developmental stages using epidural mu (morphine sulphate), delta (DPDPE) and kappa (U69593) opioid receptor agonists in neonatal rats aged P ...
	Epidural opioid analgesia in infant rats I: mechanical and heat responses. Pain, Vol. 82, No. 1. (July 1999), pp. 23-32. by D. Marsh, A. Dickenson, D. Hatch, M. Fitzgerald posted to analgesia opiates pain rat by fdbuck0 to the group Fetal_Pain on 2005-12-22 16:04:01 Abstract Copy My Attachments My Copy Abstract The aim of this study was to investigate the analgesic effects of epidural opioids in neonatal rat pups. The contribution of individual opioid receptor subtypes in the spinal cord to analgesia at different developmental stages was investigated using epidural mu (morphine sulphate), delta (DPDPE) and kappa (U69593) opioid receptor agonists in neonatal rats aged postnatal day (P) 3, 10 and 21. Thresholds for flexion withdrawal reflexes to mechanical stimuli (von Frey hairs) and to noxious heating of the hind paw were ...
	Opioid analgesia in the newborn. Eur J Pain, Vol. 9, No. 2. (April 2005), pp. 105-108. by R. Nandi, M. Fitzgerald posted to analgesia neonatal opiates pain by fdbuck0 to the group Fetal_Pain on 2005-12-22 10:53:28 Abstract Copy My Attachments My Copy Abstract Pain in neonates is now well established. Studies of the developmental neurobiology of pain have revealed that pain processing in the immature is very different from that in the mature nervous system. Neonates undergo considerable maturation of peripheral, spinal and supraspinal afferent pain transmission over the early postnatal period but are able to respond to tissue injury with specific behaviour and with autonomic, hormonal and metabolic signs of stress and distress. Opioid analgesia is now widely used in neonates. There is ...

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