Cellular segregation and engulfment simulations using the cell programming language Export

@article{citeulike:5352857, abstract = {In developmental biology, modeling and simulation play an important role in understanding cellular interactions. In this paper a simple language, the Cell Programming Language (CPL), is suggested for writing programs that describe this behavior. Using these programs, it is possible to simulate and visualize intercellular behavior. CPL is used to model cellular segregation based upon the differential adhesion hypothesis. Results indicate that a high degree of segregation can be produced in a mixture of cells by allowing random motion. The engulfment of a tissue by a less adhesive tissue is also observed when the two tissues are placed in contact. Both these simulations utilize only local interactions and random motion of cells. Earlier simulations used long-range interactions to observe similar effects. The present simulations prove that random motion of cells can produce long-range effects.}, author = {Agarwal, P.}, citeulike-article-id = {5352857}, citeulike-linkout-0 = {http://dx.doi.org/10.1006/jtbi.1995.0178}, citeulike-linkout-1 = {http://linkinghub.elsevier.com/retrieve/pii/S0022-5193(85)70178-6}, citeulike-linkout-2 = {http://view.ncbi.nlm.nih.gov/pubmed/7475109}, citeulike-linkout-3 = {http://www.hubmed.org/display.cgi?uids=7475109}, day = {07}, doi = {10.1006/jtbi.1995.0178}, issn = {00225193}, journal = {Journal of Theoretical Biology}, keywords = {alife, development, morphogenesis}, month = {September}, number = {1}, pages = {79--89}, posted-at = {2009-10-13 14:42:32}, priority = {2}, title = {Cellular segregation and engulfment simulations using the cell programming language}, url = {http://dx.doi.org/10.1006/jtbi.1995.0178}, volume = {176}, year = {1995} }

TY - JOUR ID - citeulike:5352857 L3 - citeulike-article-id:5352857 N2 - In developmental biology, modeling and simulation play an important role in understanding cellular interactions. In this paper a simple language, the Cell Programming Language (CPL), is suggested for writing programs that describe this behavior. Using these programs, it is possible to simulate and visualize intercellular behavior. CPL is used to model cellular segregation based upon the differential adhesion hypothesis. Results indicate that a high degree of segregation can be produced in a mixture of cells by allowing random motion. The engulfment of a tissue by a less adhesive tissue is also observed when the two tissues are placed in contact. Both these simulations utilize only local interactions and random motion of cells. Earlier simulations used long-range interactions to observe similar effects. The present simulations prove that random motion of cells can produce long-range effects. IS - 1 JF - Journal of Theoretical Biology SN - 00225193 EP - 89 TI - Cellular segregation and engulfment simulations using the cell programming language VL - 176 SP - 79 KW - alife KW - development KW - morphogenesis AU - Agarwal, P PY - 1995/09/07/ UR - http://dx.doi.org/10.1006/jtbi.1995.0178 ER -