Role of Estrogens in Adipocyte Development and Function Export

@article{citeulike:1331723, abstract = {Estrogen has historically been viewed as a major regulator of adipose tissue in adult females, but recent work has indicated that estrogen's role in adipose biology may be broader than initially appreciated and has also provided important insights into the mechanism of estrogen effects on adipose tissue. Estrogen has direct effects on adipocytes to inhibit lipogenesis and may also have direct effects on other cellular constituents of adipose tissue, as well as metabolic effects on other target organs that can regulate adipose tissue. Estrogen has central effects on food consumption and energy expenditure that contribute to its overall inhibitory effects on adipose deposition. Estrogen also plays an important role in regulating adipose deposition in males and recently has been shown to be an important factor in the determination of adipocyte number, indicating that it regulates key developmental events in adipogenesis. Although critical questions still remain in our understanding of the overall role of estrogen in adipose tissue, it is clear that estrogen plays a more important role in adipose tissue than originally realized and that it is a major regulator of adipose tissue in both sexes during development and adulthood.}, author = {Cooke, Paul S. and Naaz, Afia}, citeulike-article-id = {1331723}, citeulike-linkout-0 = {http://www.ebmonline.org/cgi/content/abstract/229/11/1127}, citeulike-linkout-1 = {http://view.ncbi.nlm.nih.gov/pubmed/15564439}, citeulike-linkout-2 = {http://www.hubmed.org/display.cgi?uids=15564439}, day = {1}, journal = {Experimental Biology and Medicine}, keywords = {adipocytes}, month = {December}, number = {11}, pages = {1127--1135}, posted-at = {2009-07-06 10:34:25}, priority = {3}, title = {Role of Estrogens in Adipocyte Development and Function}, url = {http://www.ebmonline.org/cgi/content/abstract/229/11/1127}, volume = {229}, year = {2004} }

TY - JOUR ID - citeulike:1331723 L3 - citeulike-article-id:1331723 N2 - Estrogen has historically been viewed as a major regulator of adipose tissue in adult females, but recent work has indicated that estrogen's role in adipose biology may be broader than initially appreciated and has also provided important insights into the mechanism of estrogen effects on adipose tissue. Estrogen has direct effects on adipocytes to inhibit lipogenesis and may also have direct effects on other cellular constituents of adipose tissue, as well as metabolic effects on other target organs that can regulate adipose tissue. Estrogen has central effects on food consumption and energy expenditure that contribute to its overall inhibitory effects on adipose deposition. Estrogen also plays an important role in regulating adipose deposition in males and recently has been shown to be an important factor in the determination of adipocyte number, indicating that it regulates key developmental events in adipogenesis. Although critical questions still remain in our understanding of the overall role of estrogen in adipose tissue, it is clear that estrogen plays a more important role in adipose tissue than originally realized and that it is a major regulator of adipose tissue in both sexes during development and adulthood. IS - 11 JF - Experimental Biology and Medicine EP - 1135 TI - Role of Estrogens in Adipocyte Development and Function VL - 229 SP - 1127 KW - adipocytes AU - Cooke, Paul AU - Naaz, Afia PY - 2004/12/01/ UR - http://www.ebmonline.org/cgi/content/abstract/229/11/1127 ER -