Serotonin inhibition of the NMDA receptor/nitric oxide/cyclic GMP pathway in rat cerebellum : Involvement of 5-hydroxytryptamine2C receptors Export

@article{citeulike:3170925, abstract = {Previous studies have shown that 5-hydroxytryptamine (5-HT) can potently inhibit glutamatergic transmission in rat cerebellum through the activation of multiple 5-HT receptors. The aim of this study was to subclassify the 5-HT2 receptor mediating inhibition of the cyclic GMP response elicited by N-methyl-o-aspartate in adult rat cerebellar slices. Seven receptor antagonists, endowed with relative selectivities for the 5-HT2A, 5-HT2B, and 5-HT2C subtypes, differentially affected the inhibition by (±)-1-(2,5-dimethoxy-4-iodophenyl ) -2-aminopropane of the cyclic GMP response, suggesting that the receptor involved belongs to the 5-HT2C subtype.}, author = {Marcoli, M. and Maura, G. and Tortarolo, M. and Raiteri, M.}, citeulike-article-id = {3170925}, journal = {Journal of neurochemistry}, keywords = {5ht, nmda, serotonin}, number = {1}, pages = {427--430}, posted-at = {2008-08-29 02:13:02}, priority = {3}, title = {Serotonin inhibition of the NMDA receptor/nitric oxide/cyclic GMP pathway in rat cerebellum : Involvement of 5-hydroxytryptamine2C receptors}, volume = {69}, year = {1997} }

TY - JOUR ID - citeulike:3170925 L3 - citeulike-article-id:3170925 N2 - Previous studies have shown that 5-hydroxytryptamine (5-HT) can potently inhibit glutamatergic transmission in rat cerebellum through the activation of multiple 5-HT receptors. The aim of this study was to subclassify the 5-HT2 receptor mediating inhibition of the cyclic GMP response elicited by N-methyl-o-aspartate in adult rat cerebellar slices. Seven receptor antagonists, endowed with relative selectivities for the 5-HT2A, 5-HT2B, and 5-HT2C subtypes, differentially affected the inhibition by (±)-1-(2,5-dimethoxy-4-iodophenyl ) -2-aminopropane of the cyclic GMP response, suggesting that the receptor involved belongs to the 5-HT2C subtype. IS - 1 JF - Journal of neurochemistry EP - 430 TI - Serotonin inhibition of the NMDA receptor/nitric oxide/cyclic GMP pathway in rat cerebellum : Involvement of 5-hydroxytryptamine2C receptors VL - 69 SP - 427 KW - 5ht KW - nmda KW - serotonin AU - Marcoli, M AU - Maura, G AU - Tortarolo, M AU - Raiteri, M PY - 1997/// ER -