Sequential Processing of Lexical, Grammatical, and Phonological Information Within Broca's Area Export

@article{Sahinetal09, abstract = {Words, grammar, and phonology are linguistically distinct, yet their neural substrates are difficult to distinguish in macroscopic brain regions. We investigated whether they can be separated in time and space at the circuit level using intracranial electrophysiology (ICE), namely by recording local field potentials from populations of neurons using electrodes implanted in language-related brain regions while people read words verbatim or grammatically inflected them (present/past or singular/plural). Neighboring probes within Broca's area revealed distinct neuronal activity for lexical (\~{}200 milliseconds), grammatical (\~{}320 milliseconds), and phonological (\~{}450 milliseconds) processing, identically for nouns and verbs, in a region activated in the same patients and task in functional magnetic resonance imaging. This suggests that a linguistic processing sequence predicted on computational grounds is implemented in the brain in fine-grained spatiotemporally patterned activity. 10.1126/science.1174481}, author = {Sahin, Ned T. and Pinker, Steven and Cash, Sydney S. and Schomer, Donald and Halgren, Eric}, citeulike-article-id = {5949946}, citeulike-linkout-0 = {http://dx.doi.org/10.1126/science.1174481}, citeulike-linkout-1 = {http://www.sciencemag.org/content/326/5951/445.abstract}, citeulike-linkout-2 = {http://www.sciencemag.org/content/326/5951/445.full.pdf}, citeulike-linkout-3 = {http://view.ncbi.nlm.nih.gov/pubmed/19833971}, citeulike-linkout-4 = {http://www.hubmed.org/display.cgi?uids=19833971}, day = {16}, doi = {10.1126/science.1174481}, journal = {Science}, keywords = {broca, cognition, inflection, intracranial-recording, language, methodology, patients}, month = {October}, number = {5951}, pages = {445--449}, posted-at = {2009-10-19 10:19:34}, priority = {2}, title = {Sequential Processing of Lexical, Grammatical, and Phonological Information Within Broca's Area}, url = {http://dx.doi.org/10.1126/science.1174481}, volume = {326}, year = {2009} }

TY - JOUR ID - Sahinetal09 L3 - citeulike-article-id:5949946 N2 - Words, grammar, and phonology are linguistically distinct, yet their neural substrates are difficult to distinguish in macroscopic brain regions. We investigated whether they can be separated in time and space at the circuit level using intracranial electrophysiology (ICE), namely by recording local field potentials from populations of neurons using electrodes implanted in language-related brain regions while people read words verbatim or grammatically inflected them (present/past or singular/plural). Neighboring probes within Broca's area revealed distinct neuronal activity for lexical (~200 milliseconds), grammatical (~320 milliseconds), and phonological (~450 milliseconds) processing, identically for nouns and verbs, in a region activated in the same patients and task in functional magnetic resonance imaging. This suggests that a linguistic processing sequence predicted on computational grounds is implemented in the brain in fine-grained spatiotemporally patterned activity. 10.1126/science.1174481 IS - 5951 JF - Science EP - 449 TI - Sequential Processing of Lexical, Grammatical, and Phonological Information Within Broca's Area VL - 326 SP - 445 KW - broca KW - cognition KW - inflection KW - intracranial-recording KW - language KW - methodology KW - patients AU - Sahin, Ned AU - Pinker, Steven AU - Cash, Sydney AU - Schomer, Donald AU - Halgren, Eric PY - 2009/10/16/ UR - http://dx.doi.org/10.1126/science.1174481 ER -