Levels of lipid peroxidation, nitric oxide, and antioxidant vitamins in plasma of patients with fibromyalgia Export

@article{citeulike:4235668, abstract = {The etiology of fibromyalgia is not clearly understood. In recent years, a few studies have investigated the possible role of reactive oxygen species (ROS) in the etiology and pathogenesis of fibromyalgia. The aim of this study was to investigate plasma antioxidant vitamins, lipid peroxidation (LP), and nitric oxide (NO) levels in patients with fibromyalgia and controls. The study was performed on the blood plasma of 30 female patients and 30 age-matched controls. After a fast of 12 h, blood samples were taken, and plasma samples were obtained for measurement of vitamins A, C, E, and beta-carotene concentrations and levels of LP and NO. Concentrations of vitamins A (p \< 0.01) and E (p \< 0.001) were significantly lower in patients with fibromyalgia than in controls, and LP levels were significantly (p \< 0.05) higher in the plasma of the patients than in controls. Concentrations of vitamin C and beta-carotene and levels of NO did not change significantly. These results provide some evidence for a potential role of LP and fat-soluble antioxidants in the patients with fibromyalgia. Copyright {\copyright} 2009 John Wiley \& Sons, Ltd.}, address = {Medical Faculty, Department of Physical Medicine and Rehabilitation, Suleyman Demirel University, Isparta, Turkey; Medical Faculty, Department of Biophysics, Suleyman Demirel University, Isparta, Turkey; Medical Faculty, Department of Biochemistry, Suleyman Demirel University, Isparta, Turkey}, author = {Akku\ş, Selami and Naz\ıro\ğlu, Mustafa and Eri\ş, Sevilay and Yalman, Kadir and Y\ılmaz, Nigar and Yener, Mahmut}, citeulike-article-id = {4235668}, citeulike-linkout-0 = {http://dx.doi.org/10.1002/cbf.1548}, citeulike-linkout-1 = {http://www3.interscience.wiley.com/cgi-bin/abstract/122242531/ABSTRACT}, doi = {10.1002/cbf.1548}, journal = {Cell Biochemistry and Function}, keywords = {antioxidants, fibromyalgia, lipid\_peroxidation, nitric\_oxide}, number = {9999}, pages = {n/a+}, posted-at = {2009-03-30 01:20:14}, priority = {3}, title = {Levels of lipid peroxidation, nitric oxide, and antioxidant vitamins in plasma of patients with fibromyalgia}, url = {http://dx.doi.org/10.1002/cbf.1548}, volume = {9999}, year = {2009} }

TY - JOUR ID - citeulike:4235668 L3 - citeulike-article-id:4235668 N2 - The etiology of fibromyalgia is not clearly understood. In recent years, a few studies have investigated the possible role of reactive oxygen species (ROS) in the etiology and pathogenesis of fibromyalgia. The aim of this study was to investigate plasma antioxidant vitamins, lipid peroxidation (LP), and nitric oxide (NO) levels in patients with fibromyalgia and controls. The study was performed on the blood plasma of 30 female patients and 30 age-matched controls. After a fast of 12 h, blood samples were taken, and plasma samples were obtained for measurement of vitamins A, C, E, and beta-carotene concentrations and levels of LP and NO. Concentrations of vitamins A (p < 0.01) and E (p < 0.001) were significantly lower in patients with fibromyalgia than in controls, and LP levels were significantly (p < 0.05) higher in the plasma of the patients than in controls. Concentrations of vitamin C and beta-carotene and levels of NO did not change significantly. These results provide some evidence for a potential role of LP and fat-soluble antioxidants in the patients with fibromyalgia. Copyright © 2009 John Wiley & Sons, Ltd. IS - 9999 JF - Cell Biochemistry and Function AD - Medical Faculty, Department of Physical Medicine and Rehabilitation, Suleyman Demirel University, Isparta, Turkey; Medical Faculty, Department of Biophysics, Suleyman Demirel University, Isparta, Turkey; Medical Faculty, Department of Biochemistry, Suleyman Demirel University, Isparta, Turkey TI - Levels of lipid peroxidation, nitric oxide, and antioxidant vitamins in plasma of patients with fibromyalgia VL - 9999 SP - n/a KW - antioxidants KW - fibromyalgia KW - lipid_peroxidation KW - nitric_oxide AU - Akkuş, Selami AU - Nazıroğlu, Mustafa AU - Eriş, Sevilay AU - Yalman, Kadir AU - Yılmaz, Nigar AU - Yener, Mahmut PY - 2009/// UR - http://dx.doi.org/10.1002/cbf.1548 ER -