Bacterial Community Variation in Human Body Habitats Across Space and Time Export

@article{citeulike:6081240, abstract = {Elucidating the biogeography of bacterial communities on the human body is critical for establishing healthy baselines from which to detect differences associated with diseases. To obtain an integrated view of the spatial and temporal distribution of the human microbiota, we surveyed bacteria from up to 27 sites in 7 to 9 healthy adults on four occasions. We found that community composition was determined primarily by body habitat. Within habitats, interpersonal variability was high, while individuals exhibited minimal temporal variability. Several skin locations harbored more diverse communities than the gut and mouth, and skin locations differed in their community assembly patterns. These results indicate that our microbiota, although personalized, varies systematically across body habitats and time: Such trends may ultimately reveal how microbiome changes cause or prevent disease. 10.1126/science.1177486}, author = {Costello, Elizabeth K. and Lauber, Christian L. and Hamady, Micah and Fierer, Noah and Gordon, Jeffrey I. and Knight, Rob}, citeulike-article-id = {6081240}, citeulike-linkout-0 = {http://dx.doi.org/10.1126/science.1177486}, citeulike-linkout-1 = {http://www.sciencemag.org/content/1177486/.abstract}, citeulike-linkout-2 = {http://www.sciencemag.org/content/1177486/.full.pdf}, citeulike-linkout-3 = {http://view.ncbi.nlm.nih.gov/pubmed/19892944}, citeulike-linkout-4 = {http://www.hubmed.org/display.cgi?uids=19892944}, day = {5}, doi = {10.1126/science.1177486}, journal = {Science}, keywords = {bacterial\_communities, biogeography, community\_assembly, community\_composition, human, microbiome, microbiota, microflora, temporal\_variability}, month = {November}, pages = {1177486+}, posted-at = {2009-11-06 16:32:29}, priority = {2}, title = {Bacterial Community Variation in Human Body Habitats Across Space and Time}, url = {http://dx.doi.org/10.1126/science.1177486}, year = {2009} }

TY - JOUR ID - citeulike:6081240 L3 - citeulike-article-id:6081240 N2 - Elucidating the biogeography of bacterial communities on the human body is critical for establishing healthy baselines from which to detect differences associated with diseases. To obtain an integrated view of the spatial and temporal distribution of the human microbiota, we surveyed bacteria from up to 27 sites in 7 to 9 healthy adults on four occasions. We found that community composition was determined primarily by body habitat. Within habitats, interpersonal variability was high, while individuals exhibited minimal temporal variability. Several skin locations harbored more diverse communities than the gut and mouth, and skin locations differed in their community assembly patterns. These results indicate that our microbiota, although personalized, varies systematically across body habitats and time: Such trends may ultimately reveal how microbiome changes cause or prevent disease. 10.1126/science.1177486 JF - Science TI - Bacterial Community Variation in Human Body Habitats Across Space and Time SP - 1177486 KW - bacterial_communities KW - biogeography KW - community_assembly KW - community_composition KW - human KW - microbiome KW - microbiota KW - microflora KW - temporal_variability AU - Costello, Elizabeth AU - Lauber, Christian AU - Hamady, Micah AU - Fierer, Noah AU - Gordon, Jeffrey AU - Knight, Rob PY - 2009/11/05/ UR - http://dx.doi.org/10.1126/science.1177486 ER -