Comparative metagenomics of microbial communities. Export

@article{citeulike:700422, abstract = {The species complexity of microbial communities and challenges in culturing representative isolates make it difficult to obtain assembled genomes. Here we characterize and compare the metabolic capabilities of terrestrial and marine microbial communities using largely unassembled sequence data obtained by shotgun sequencing DNA isolated from the various environments. Quantitative gene content analysis reveals habitat-specific fingerprints that reflect known characteristics of the sampled environments. The identification of environment-specific genes through a gene-centric comparative analysis presents new opportunities for interpreting and diagnosing environments.}, author = {Tringe, Susannah Green G. and von Mering, Christian and Kobayashi, Arthur and Salamov, Asaf A. and Chen, Kevin and Chang, Hwai W. and Podar, Mircea and Short, Jay M. and Mathur, Eric J. and Detter, John C. and Bork, Peer and Hugenholtz, Philip and Rubin, Edward M.}, citeulike-article-id = {700422}, citeulike-linkout-0 = {http://dx.doi.org/10.1126/science.1107851}, citeulike-linkout-1 = {http://www.sciencemag.org/content/308/5721/554.abstract}, citeulike-linkout-2 = {http://www.sciencemag.org/content/308/5721/554.full.pdf}, citeulike-linkout-3 = {http://www.sciencemag.org/cgi/content/abstract/308/5721/554}, citeulike-linkout-4 = {http://view.ncbi.nlm.nih.gov/pubmed/15845853}, citeulike-linkout-5 = {http://www.hubmed.org/display.cgi?uids=15845853}, day = {22}, doi = {10.1126/science.1107851}, issn = {1095-9203}, journal = {Science (New York, N.Y.)}, keywords = {diversity, egts, metagenomic, ploscb08}, month = {April}, number = {5721}, pages = {554--557}, posted-at = {2008-07-25 22:59:38}, priority = {2}, title = {Comparative metagenomics of microbial communities.}, url = {http://dx.doi.org/10.1126/science.1107851}, volume = {308}, year = {2005} }

TY - JOUR ID - citeulike:700422 L3 - citeulike-article-id:700422 N2 - The species complexity of microbial communities and challenges in culturing representative isolates make it difficult to obtain assembled genomes. Here we characterize and compare the metabolic capabilities of terrestrial and marine microbial communities using largely unassembled sequence data obtained by shotgun sequencing DNA isolated from the various environments. Quantitative gene content analysis reveals habitat-specific fingerprints that reflect known characteristics of the sampled environments. The identification of environment-specific genes through a gene-centric comparative analysis presents new opportunities for interpreting and diagnosing environments. IS - 5721 JF - Science (New York, N.Y.) SN - 1095-9203 EP - 557 TI - Comparative metagenomics of microbial communities. VL - 308 SP - 554 KW - diversity KW - egts KW - metagenomic KW - ploscb08 AU - Tringe, Susannah Green AU - von Mering, Christian AU - Kobayashi, Arthur AU - Salamov, Asaf AU - Chen, Kevin AU - Chang, Hwai AU - Podar, Mircea AU - Short, Jay AU - Mathur, Eric AU - Detter, John AU - Bork, Peer AU - Hugenholtz, Philip AU - Rubin, Edward PY - 2005/04/22/ UR - http://dx.doi.org/10.1126/science.1107851 ER -