Mechanisms of heavy metal-induced autoimmunity. Export

@article{citeulike:3847090, abstract = {Chemical exposure can trigger or accelerate the development of autoimmune manifestations. Although heavy metals are elementary chemical structures, they can have profound and complex effects on the immune system. In genetically susceptible mice or rats, administration of subtoxic doses of mercury induces both the production of highly specific autoantibodies and a polyclonal activation of the immune system. We review in this article some of the mechanisms by which heavy metal exposure can lead to autoimmunity.}, author = {Rowley, B. and Monestier, M.}, citeulike-article-id = {3847090}, citeulike-linkout-0 = {http://dx.doi.org/10.1016/j.molimm.2004.07.050}, citeulike-linkout-1 = {http://view.ncbi.nlm.nih.gov/pubmed/15829271}, citeulike-linkout-2 = {http://www.hubmed.org/display.cgi?uids=15829271}, doi = {10.1016/j.molimm.2004.07.050}, issn = {0161-5890}, journal = {Molecular immunology}, keywords = {autoimmunity, chemically-induced\_autoimmunity, heavy\_metals}, month = {May}, number = {7}, pages = {833--838}, posted-at = {2009-01-04 14:35:41}, priority = {3}, title = {Mechanisms of heavy metal-induced autoimmunity.}, url = {http://dx.doi.org/10.1016/j.molimm.2004.07.050}, volume = {42}, year = {2005} }

TY - JOUR ID - citeulike:3847090 L3 - citeulike-article-id:3847090 N2 - Chemical exposure can trigger or accelerate the development of autoimmune manifestations. Although heavy metals are elementary chemical structures, they can have profound and complex effects on the immune system. In genetically susceptible mice or rats, administration of subtoxic doses of mercury induces both the production of highly specific autoantibodies and a polyclonal activation of the immune system. We review in this article some of the mechanisms by which heavy metal exposure can lead to autoimmunity. IS - 7 JF - Molecular immunology SN - 0161-5890 EP - 838 TI - Mechanisms of heavy metal-induced autoimmunity. VL - 42 SP - 833 KW - autoimmunity KW - chemically-induced_autoimmunity KW - heavy_metals AU - Rowley, B AU - Monestier, M PY - 2005/05// UR - http://dx.doi.org/10.1016/j.molimm.2004.07.050 ER -