Group: HEIRS Pharmacy and Drug Research - Bartelink [1 article]

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Intestinal Permeability in Irritable Bowel Syndrome Patients: Effects of NSAIDs

Digestive Diseases and Sciences

by Angèle Kerckhoffs, Louis Akkermans, Martin de Smet, et al.Marc Besselink, Falco Hietbrink, Imke Bartelink, Wim Busschers, Melvin Samsom, Willem Renooij

posted to ibs intestinal_permeability nsaids by HEIRS to the group HEIRS Pharmacy and Drug Research on 2009-03-08 09:17:16

along with 4 groups HEIRS Inflammatory Bowel Disease, Colititis, and IBS HEIRS Immunology and Autoimmune Diseases HEIRS - Environmental Illness Research HEIRS Cellular Biology

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Abstract

Abstract Intestinal permeability and the effect of NSAIDs on permeability were investigated in 14 irritable bowel syndrome (IBS) patients and 15 healthy subjects. In the study, 24-h urinary recoveries of orally administered polyethylene glycols (PEGs 400, 1500, and 4000) were not significantly different in healthy subjects and IBS patients before or after NSAID ingestion. Lactulose mannitol ratios in healthy subjects and IBS patients were not significantly different. Only time-dependent monitoring of PEG excretion showed that NSAIDs enhanced intestinal permeability for PEG 4000 ...

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Group: HEIRS Pharmacy and Drug Research

Group: HEIRS Pharmacy and Drug Research - Bartelink [1 article]

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