Cytokines and their relationship to the symptoms and outcome of cancer Export

@article{citeulike:3449997, abstract = {Tumours contain immune cells and a network of pro- and anti-inflammatory cytokines, which collaborate in the development and progression of cancer. Cytokine profiles might prove to be prognostic. The systemic effects of pro-inflammatory cytokines are associated with fatigue, depression and cognitive impairment, and can affect quality of life before, during and after treatment. In people with advanced cancer, pro-inflammatory cytokines are additionally associated with anorexia and cachexia, pain, toxicity of treatment and resistance to treatment. However, physical activity might modify cytokine levels and decrease fatigue in patients with cancer, and might also improve their prognosis.}, author = {Seruga, Bostjan and Zhang, Haibo and Bernstein, Lori J. and Tannock, Ian F.}, citeulike-article-id = {3449997}, citeulike-linkout-0 = {http://dx.doi.org/10.1038/nrc2507}, citeulike-linkout-1 = {http://dx.doi.org/10.1038/nrc2507}, day = {10}, doi = {10.1038/nrc2507}, issn = {1474-175X}, journal = {Nature Reviews Cancer}, keywords = {bcdc, cancer, cancer-crosstalk, cytokine, outcomes, promise, symptoms, thesis}, month = {October}, number = {11}, pages = {887--899}, posted-at = {2008-11-06 18:11:20}, priority = {2}, publisher = {Nature Publishing Group}, title = {Cytokines and their relationship to the symptoms and outcome of cancer}, url = {http://dx.doi.org/10.1038/nrc2507}, volume = {8}, year = {2008} }

TY - JOUR ID - citeulike:3449997 L3 - citeulike-article-id:3449997 N2 - Tumours contain immune cells and a network of pro- and anti-inflammatory cytokines, which collaborate in the development and progression of cancer. Cytokine profiles might prove to be prognostic. The systemic effects of pro-inflammatory cytokines are associated with fatigue, depression and cognitive impairment, and can affect quality of life before, during and after treatment. In people with advanced cancer, pro-inflammatory cytokines are additionally associated with anorexia and cachexia, pain, toxicity of treatment and resistance to treatment. However, physical activity might modify cytokine levels and decrease fatigue in patients with cancer, and might also improve their prognosis. IS - 11 JF - Nature Reviews Cancer SN - 1474-175X EP - 899 TI - Cytokines and their relationship to the symptoms and outcome of cancer PB - Nature Publishing Group VL - 8 SP - 887 KW - bcdc KW - cancer KW - cancer-crosstalk KW - cytokine KW - outcomes KW - promise KW - symptoms KW - thesis AU - Seruga, Bostjan AU - Zhang, Haibo AU - Bernstein, Lori AU - Tannock, Ian PY - 2008/10/10/ UR - http://dx.doi.org/10.1038/nrc2507 ER -