MicroRNA function in animal development Export

@article{citeulike:1378370, abstract = {MicroRNAs (miRNAs) are small non-coding RNA molecules that post-transcriptionally regulate gene expression by base-pairing to mRNAs. Hundreds of miRNAs have been identified in various multicellular organisms and many miRNAs are evolutionarily conserved. Although the biological functions of most miRNAs are unknown, miRNAs are predicted to regulate up to 30\% of the genes within the human genome. Gradually, we are beginning to understand the functions of individual miRNAs and the general function of miRNA action. Here, we review the recent advances in miRNA biology in animals. Particularly, we focus on the roles of miRNAs in vertebrate development and disease.}, author = {Wienholds, Erno and Plasterk, Ronald H.}, booktitle = {RNAi: Mechanisms, Biology and Applications}, citeulike-article-id = {1378370}, citeulike-linkout-0 = {http://www.sciencedirect.com/science/article/B6T36-4GV9B5G-1/2/eb0dd9f28f956966b80f4c37e2e02a4a}, day = {31}, journal = {FEBS Letters}, keywords = {0-useful, mirna}, month = {October}, number = {26}, pages = {5911--5922}, posted-at = {2007-06-11 10:21:11}, priority = {2}, title = {MicroRNA function in animal development}, url = {http://www.sciencedirect.com/science/article/B6T36-4GV9B5G-1/2/eb0dd9f28f956966b80f4c37e2e02a4a}, volume = {579}, year = {2005} }

TY - JOUR ID - citeulike:1378370 L3 - citeulike-article-id:1378370 N2 - MicroRNAs (miRNAs) are small non-coding RNA molecules that post-transcriptionally regulate gene expression by base-pairing to mRNAs. Hundreds of miRNAs have been identified in various multicellular organisms and many miRNAs are evolutionarily conserved. Although the biological functions of most miRNAs are unknown, miRNAs are predicted to regulate up to 30% of the genes within the human genome. Gradually, we are beginning to understand the functions of individual miRNAs and the general function of miRNA action. Here, we review the recent advances in miRNA biology in animals. Particularly, we focus on the roles of miRNAs in vertebrate development and disease. IS - 26 JF - FEBS Letters EP - 5922 TI - MicroRNA function in animal development VL - 579 T2 - RNAi: Mechanisms, Biology and Applications SP - 5911 KW - 0-useful KW - mirna AU - Wienholds, Erno AU - Plasterk, Ronald PY - 2005/10/31/ UR - http://www.sciencedirect.com/science/article/B6T36-4GV9B5G-1/2/eb0dd9f28f956966b80f4c37e2e02a4a ER -