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Novel versus unsupported clades: assessing the qualitative support for clades in MRP supertrees. Export

Syst Biol, Vol. 52, No. 6. (Dec 2003), pp. 839-48.

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14668120 algorithms alignment alligators analysis and angiosperms animals array bibtex-import biodiversity calibration carnivora classification cluster comparative computer crocodiles data design dna evolution factors fossils genetic genetics govt graphics interface interpretation meta-analysis models molecular mutational non-phs non-us oligonucleotide pedigree phylogeny population re research search sequence simulation software statistical study support theoretical time us user-computer variation

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Matrix representation with parsimony (MRP) supertree construction has been criticized because the supertree may specify clades that are contradicted by every source tree contributing to it. Such unsupported clades may also occur using other supertree methods; however, their incidence is largely unknown. In this study, I investigated the frequency of unsupported clades in both simulated and empirical MRP supertrees. Here, I propose a new index, QS, to quantify the qualitative support for a supertree and its clades among the set of source trees. Results show that unsupported clades are very rare in MRP supertrees, occurring most often when there are few source trees that all possess the same set of taxa. However, even under these conditions the frequency of unsupported clades was <0.2\%. Unsupported clades were absent from both the Carnivora and Lagomorpha supertrees, reflecting the use of large numbers of source trees for both. The proposed QS indices are correlated broadly with another measure of quantitative clade support (bootstrap frequencies, as derived from resampling of the MRP matrix) but appear to be more sensitive. More importantly, they sample at the level of the source trees and thus, unlike the bootstrap, are suitable for summarizing the support of MRP supertree clades.


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