Oestrogenicity of paper and cardboard extracts used as food containers Export

@article{citeulike:3371787, abstract = {Bisphenol-A (BPA), dibutyl phthalate (DBP), and di-2-ethylhexyl phthalate (DEHP), which are common chemical residues in food-packaging materials, were investigated in paper and cardboard containers used for take-away food. The oestrogenicity of aqueous extracts was tested in E-Screen bioassay and analysis carried out by high-performance liquid chromatography (HPLC) and gas chromatography-mass spectrometry (GC/MS). Oestrogenicity was demonstrated in 90\% of extracts (geometric mean [GM]\&thinsp;=\&thinsp;11.97\&thinsp;pM oestradiol equivalents\&thinsp;g^-1). DEHP, DBP, and BPA (GM\&thinsp;=\&thinsp;341.74, 37.59, and 2.38\&thinsp;ng\&thinsp;g^-1 of material) were present in 77.50, 67.50, and 47.50\% of samples, respectively. In bivariate analyses, no significant association was found between the levels of these chemicals and oestrogenicity in cardboard/paper extracts. A close-to-significant association was found between oestrogenicity and DBP (<i>\&b.beta;</i>\&thinsp;=\&thinsp;1.25; <i>p</i>\&thinsp;=\&thinsp;0.06) in paper extracts, which reached statistical significance in multivariate analysis (<i>\&b.beta;</i>\&thinsp;=\&thinsp;1.61; <i>p</i>\&thinsp;=\&thinsp;0.03). Paper and cardboard used in food packaging may contribute to the inadvertent exposure of consumers to endocrine-disrupting chemicals.}, author = {Lopez-Espinosa and Granada, A. and Araque, P. and Molina-Molina and Puertollano and Rivas, A. and Fern\'{a}ndez, M. and Cerrillo, I. and Olea-Serrano and L\'{o}pez, C. and Olea, N.}, citeulike-article-id = {3371787}, citeulike-linkout-0 = {http://dx.doi.org/10.1080/02652030600936375}, citeulike-linkout-1 = {http://view.ncbi.nlm.nih.gov/pubmed/17164220}, citeulike-linkout-2 = {http://www.hubmed.org/display.cgi?uids=17164220}, doi = {10.1080/02652030600936375}, journal = {Food Additives \& Contaminants: Part A: Chemistry, Analysis, Control, Exposure \& Risk Assessment}, keywords = {cardboard, e-screen, estrogen, packaging, thesis}, number = {1}, pages = {95--102}, posted-at = {2008-10-03 21:53:54}, priority = {2}, publisher = {Taylor \& Francis}, title = {Oestrogenicity of paper and cardboard extracts used as food containers}, url = {http://dx.doi.org/10.1080/02652030600936375}, volume = {24}, year = {2007} }

TY - JOUR ID - citeulike:3371787 L3 - citeulike-article-id:3371787 N2 - Bisphenol-A (BPA), dibutyl phthalate (DBP), and di-2-ethylhexyl phthalate (DEHP), which are common chemical residues in food-packaging materials, were investigated in paper and cardboard containers used for take-away food. The oestrogenicity of aqueous extracts was tested in E-Screen bioassay and analysis carried out by high-performance liquid chromatography (HPLC) and gas chromatography-mass spectrometry (GC/MS). Oestrogenicity was demonstrated in 90% of extracts (geometric mean [GM]&thinsp;=&thinsp;11.97&thinsp;pM oestradiol equivalents&thinsp;g^-1). DEHP, DBP, and BPA (GM&thinsp;=&thinsp;341.74, 37.59, and 2.38&thinsp;ng&thinsp;g^-1 of material) were present in 77.50, 67.50, and 47.50% of samples, respectively. In bivariate analyses, no significant association was found between the levels of these chemicals and oestrogenicity in cardboard/paper extracts. A close-to-significant association was found between oestrogenicity and DBP (<i>&b.beta;</i>&thinsp;=&thinsp;1.25; <i>p</i>&thinsp;=&thinsp;0.06) in paper extracts, which reached statistical significance in multivariate analysis (<i>&b.beta;</i>&thinsp;=&thinsp;1.61; <i>p</i>&thinsp;=&thinsp;0.03). Paper and cardboard used in food packaging may contribute to the inadvertent exposure of consumers to endocrine-disrupting chemicals. IS - 1 JF - Food Additives & Contaminants: Part A: Chemistry, Analysis, Control, Exposure & Risk Assessment EP - 102 TI - Oestrogenicity of paper and cardboard extracts used as food containers PB - Taylor & Francis VL - 24 SP - 95 KW - cardboard KW - e-screen KW - estrogen KW - packaging KW - thesis AU - Lopez-Espinosa AU - Granada, A AU - Araque, P AU - Molina-Molina AU - Puertollano AU - Rivas, A AU - Fernández, M AU - Cerrillo, I AU - Olea-Serrano AU - López, C AU - Olea, N PY - 2007/// UR - http://dx.doi.org/10.1080/02652030600936375 ER -