Phytoestrogens oestrogen synthesis and breast cancer☆ Export

@article{citeulike:3498628, abstract = {Phytoestrogens are used as \&\#x2018;natural\&\#x2019; alternatives to HRT and, although epidemiological evidence implies that diets rich in phytoestrogens reduce the incidence of breast cancer, their weak oestrogenicity is also known to stimulate growth in experimental models of breast cancer. This review addresses the question as to how phytoestrogens may protect against breast cancer through their ability to bind preferentially to oestrogen receptor \&\#x3b2;, inhibit enzymes that convert circulating steroid precursors into oestradiol and inhibit cell signalling pathways of growth factors.}, author = {Rice, S. and Whitehead, S.}, citeulike-article-id = {3498628}, citeulike-linkout-0 = {http://dx.doi.org/10.1016/j.jsbmb.2007.09.003}, citeulike-linkout-1 = {http://linkinghub.elsevier.com/retrieve/pii/S0960076007002488}, doi = {10.1016/j.jsbmb.2007.09.003}, issn = {09600760}, journal = {The Journal of Steroid Biochemistry and Molecular Biology}, keywords = {alternative, breast, cancer, estrogen, hrt, phytoestrogen, therapy}, month = {February}, number = {3-5}, pages = {186--195}, posted-at = {2008-11-09 18:16:35}, priority = {2}, title = {Phytoestrogens oestrogen synthesis and breast cancer☆}, url = {http://dx.doi.org/10.1016/j.jsbmb.2007.09.003}, volume = {108}, year = {2008} }

TY - JOUR ID - citeulike:3498628 L3 - citeulike-article-id:3498628 N2 - Phytoestrogens are used as ‘natural’ alternatives to HRT and, although epidemiological evidence implies that diets rich in phytoestrogens reduce the incidence of breast cancer, their weak oestrogenicity is also known to stimulate growth in experimental models of breast cancer. This review addresses the question as to how phytoestrogens may protect against breast cancer through their ability to bind preferentially to oestrogen receptor β, inhibit enzymes that convert circulating steroid precursors into oestradiol and inhibit cell signalling pathways of growth factors. IS - 3-5 JF - The Journal of Steroid Biochemistry and Molecular Biology SN - 09600760 EP - 195 TI - Phytoestrogens oestrogen synthesis and breast cancer☆ VL - 108 SP - 186 KW - alternative KW - breast KW - cancer KW - estrogen KW - hrt KW - phytoestrogen KW - therapy AU - Rice, S AU - Whitehead, S PY - 2008/02// UR - http://dx.doi.org/10.1016/j.jsbmb.2007.09.003 ER -