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Breast Cancer Single-Nucleotide Polymorphisms: Statistical Significance and Clinical Utilityby: Kenneth Offit
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Abstract10.1093/jnci/djp184 The completion of nine large genome-wide association studies (1–9) has focused attention on single-nucleotide polymorphisms (SNPs) as risk factors for breast cancer. Despite considerable progress, the scientific yield, practical application, and commercial exploitation of SNP profiling for disease risk remain topics of debate
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