ERK1/2 and CaMKII-mediated events in memory formation: is 5HT regulation involved? Export

@article{citeulike:3520942, abstract = {Activity-dependent changes in neuronal efficacy underlie the formation and storage of new memories. Several studies indicate that modification of the phosphorylation/activation state of different protein kinases localized in the synapses or the nucleus plays a critical role in the induction and maintenance of plastic mechanisms and in the consolidation of long-lasting memories. Here we review some of the more recent findings concerning the regulation of two of the main protein kinase groups involved in memory processes and in neuronal plasticity: Ca2+/calmodulin-dependent protein kinase II (CaMKII), and the mitogen-activated protein kinase (MAPK) family. Since this issue of the journal is dedicated to serotonin (5HT) regulation of behavior, we will comment on the so far scanty, but significant, evidence for a role of 5HT in the regulation of CaMKII and MAPK.}, author = {Cammarota, M. and Bevilaqua, L. R. and Medina, J. H. and Izquierdo, I.}, citeulike-article-id = {3520942}, citeulike-linkout-0 = {http://dx.doi.org/10.1016/j.bbr.2007.11.029}, citeulike-linkout-1 = {http://view.ncbi.nlm.nih.gov/pubmed/18242725}, citeulike-linkout-2 = {http://www.hubmed.org/display.cgi?uids=18242725}, day = {16}, doi = {10.1016/j.bbr.2007.11.029}, issn = {0166-4328}, journal = {Behavioural brain research}, keywords = {5ht, erk12camkii, memory}, month = {December}, number = {1}, pages = {120--128}, posted-at = {2008-11-16 02:51:34}, priority = {2}, title = {ERK1/2 and CaMKII-mediated events in memory formation: is 5HT regulation involved?}, url = {http://dx.doi.org/10.1016/j.bbr.2007.11.029}, volume = {195}, year = {2008} }

TY - JOUR ID - citeulike:3520942 L3 - citeulike-article-id:3520942 N2 - Activity-dependent changes in neuronal efficacy underlie the formation and storage of new memories. Several studies indicate that modification of the phosphorylation/activation state of different protein kinases localized in the synapses or the nucleus plays a critical role in the induction and maintenance of plastic mechanisms and in the consolidation of long-lasting memories. Here we review some of the more recent findings concerning the regulation of two of the main protein kinase groups involved in memory processes and in neuronal plasticity: Ca2+/calmodulin-dependent protein kinase II (CaMKII), and the mitogen-activated protein kinase (MAPK) family. Since this issue of the journal is dedicated to serotonin (5HT) regulation of behavior, we will comment on the so far scanty, but significant, evidence for a role of 5HT in the regulation of CaMKII and MAPK. IS - 1 JF - Behavioural brain research SN - 0166-4328 EP - 128 TI - ERK1/2 and CaMKII-mediated events in memory formation: is 5HT regulation involved? VL - 195 SP - 120 KW - 5ht KW - erk12camkii KW - memory AU - Cammarota, M AU - Bevilaqua, LR AU - Medina, JH AU - Izquierdo, I PY - 2008/12/16/ UR - http://dx.doi.org/10.1016/j.bbr.2007.11.029 ER -