Ventral-striatal/nucleus-accumbens sensitivity to prediction errors during classification learning.

@article{citeulike:1355835, abstract = {A prominent theory in neuroscience suggests reward learning is driven by the discrepancy between a subject's expectation of an outcome and the actual outcome itself. Furthermore, it is postulated that midbrain dopamine neurons relay this mismatch to target regions including the ventral striatum. Using functional MRI (fMRI), we tested striatal responses to prediction errors for probabilistic classification learning with purely cognitive feedback. We used a version of the Rescorla-Wagner model to generate prediction errors for each subject and then entered these in a parametric analysis of fMRI activity. Activation in ventral striatum/nucleus-accumbens (Nacc) increased parametrically with prediction error for negative feedback. This result extends recent neuroimaging findings in reward learning by showing that learning with cognitive feedback also depends on the same circuitry and dopaminergic signaling mechanisms.}, address = {Department of Cognitive Science, University of California, Irvine, USA.}, author = {Rodriguez, P. F. and Aron, A. R. and Poldrack, R. A. }, citeulike-article-id = {1355835}, doi = {http://dx.doi.org/10.1002/hbm.20186}, issn = {1065-9471}, journal = {Hum Brain Mapp}, keywords = {instrumental\_conditioning, nucleus\_accumbens, reinforcement\_learning, reward\_prediction\_error, ventral\_striatum}, month = {April}, number = {4}, pages = {306--313}, posted-at = {2007-06-01 16:46:08}, priority = {2}, title = {Ventral-striatal/nucleus-accumbens sensitivity to prediction errors during classification learning.}, url = {http://dx.doi.org/10.1002/hbm.20186}, volume = {27}, year = {2006} }

TY - JOUR ID - citeulike:1355835 L3 - citeulike-article-id:1355835 TI - Ventral-striatal/nucleus-accumbens sensitivity to prediction errors during classification learning. JF - Hum Brain Mapp VL - 27 IS - 4 SP - 306 EP - 313 AD - Department of Cognitive Science, University of California, Irvine, USA. SN - 1065-9471 N2 - A prominent theory in neuroscience suggests reward learning is driven by the discrepancy between a subject's expectation of an outcome and the actual outcome itself. Furthermore, it is postulated that midbrain dopamine neurons relay this mismatch to target regions including the ventral striatum. Using functional MRI (fMRI), we tested striatal responses to prediction errors for probabilistic classification learning with purely cognitive feedback. We used a version of the Rescorla-Wagner model to generate prediction errors for each subject and then entered these in a parametric analysis of fMRI activity. Activation in ventral striatum/nucleus-accumbens (Nacc) increased parametrically with prediction error for negative feedback. This result extends recent neuroimaging findings in reward learning by showing that learning with cognitive feedback also depends on the same circuitry and dopaminergic signaling mechanisms. KW - instrumental_conditioning KW - nucleus_accumbens KW - reinforcement_learning KW - reward_prediction_error KW - ventral_striatum AU - Rodriguez, PF AU - Aron, AR AU - Poldrack, RA PY - 2006/04// UR - http://dx.doi.org/10.1002/hbm.20186 ER -