Plasma hormone profiles in populations at different risk for breast cancer. Export

@article{citeulike:3515162, abstract = {Evidence suggests that the reliability of urinary androgens or estrogens as prognostic discriminants for breast cancer may vary with different populations and may bear little relation to changes in plasma hormone levels. In this study the plasma estradiol level was significantly lower in Bantu, but did not in Caucasian, women with breast cancer, while the proportion of plasma androstenedione to dehydroepiandrosterone increased in Bantu patients. These changes in the plasma hormone profile in Bantu patients, a low-risk population for breast cancer, imply a change in ovarian and/or adrenal activity. Lack of similar hormone changes in Caucasian patients may be due to the initial differences in the hormone profile between the healthy Caucasian and Bantu women and to the different environmental factors that promote the breast disease in Western women.}, author = {Hill, P. and Wynder, E. L. and Helman, P. and Hickman, R. and Rona, G.}, citeulike-article-id = {3515162}, citeulike-linkout-0 = {http://view.ncbi.nlm.nih.gov/pubmed/131645}, citeulike-linkout-1 = {http://www.hubmed.org/display.cgi?uids=131645}, issn = {0008-5472}, journal = {Cancer research}, keywords = {bantu, comparisons, estrogen, plasma, population}, month = {June}, number = {6}, pages = {1883--1885}, posted-at = {2008-11-14 22:21:50}, priority = {2}, title = {Plasma hormone profiles in populations at different risk for breast cancer.}, url = {http://view.ncbi.nlm.nih.gov/pubmed/131645}, volume = {36}, year = {1976} }

TY - JOUR ID - citeulike:3515162 L3 - citeulike-article-id:3515162 N2 - Evidence suggests that the reliability of urinary androgens or estrogens as prognostic discriminants for breast cancer may vary with different populations and may bear little relation to changes in plasma hormone levels. In this study the plasma estradiol level was significantly lower in Bantu, but did not in Caucasian, women with breast cancer, while the proportion of plasma androstenedione to dehydroepiandrosterone increased in Bantu patients. These changes in the plasma hormone profile in Bantu patients, a low-risk population for breast cancer, imply a change in ovarian and/or adrenal activity. Lack of similar hormone changes in Caucasian patients may be due to the initial differences in the hormone profile between the healthy Caucasian and Bantu women and to the different environmental factors that promote the breast disease in Western women. IS - 6 JF - Cancer research SN - 0008-5472 EP - 1885 TI - Plasma hormone profiles in populations at different risk for breast cancer. VL - 36 SP - 1883 KW - bantu KW - comparisons KW - estrogen KW - plasma KW - population AU - Hill, P AU - Wynder, EL AU - Helman, P AU - Hickman, R AU - Rona, G PY - 1976/06// UR - http://view.ncbi.nlm.nih.gov/pubmed/131645 ER -