Clinical, hormonal and biochemical features of menopausal women in Ibadan, Nigeria. Export

@article{citeulike:3681034, abstract = {As a result of the general lack of information about the menopause in Nigeria this study was conducted to determine the prevalence of climacteric symptoms in a cohort of healthy perimenopausal women and also to evaluate the hormonal and biochemical profile of the subjects. Seventeen menopausal and 19 premenopausal women aged 40 years or more were interviewed and had venepuncture and collection of 24-h urine samples. Plasma from the blood samples was used for the assay of LH, FSH, progesterone, 17 beta-oestradiol, calcium and cholesterol while urinary calcium was determined from the 24-h urine samples. The data revealed a significant difference in the prevalence of the symptoms of vasomotor instability (hot flushes, palpitations and excessive sweating) among the menopausal group when compared with the premenopausal group. Furthermore, plasma gonadotrophin levels (LH and FSH) were significantly elevated while plasma oestradiol and progesterone levels were lower in the menopausal women than in the premenopausal group. With regards to the biochemical indices evaluated, only 24-h urinary calcium levels were found to be significantly different for the two groups, with higher levels in the menopausal women. The significance of these findings and the need for adequate screening and treatment of selected menopausal women are discussed.}, author = {Otolorin, E. O. and Adeyefa, I. and Osotimehin, B. O. and Fatinikun, T. and Ojengbede, O. and Otubu, J. O. and Ladipo, O. A.}, citeulike-article-id = {3681034}, citeulike-linkout-0 = {http://view.ncbi.nlm.nih.gov/pubmed/2558555}, citeulike-linkout-1 = {http://www.hubmed.org/display.cgi?uids=2558555}, issn = {0309-3913}, journal = {African journal of medicine and medical sciences}, keywords = {estrogen, hormone, measurement, menopausal, nigeria, profile}, month = {December}, number = {4}, pages = {251--255}, posted-at = {2008-11-24 14:29:01}, priority = {2}, title = {Clinical, hormonal and biochemical features of menopausal women in Ibadan, Nigeria.}, url = {http://view.ncbi.nlm.nih.gov/pubmed/2558555}, volume = {18}, year = {1989} }

TY - JOUR ID - citeulike:3681034 L3 - citeulike-article-id:3681034 N2 - As a result of the general lack of information about the menopause in Nigeria this study was conducted to determine the prevalence of climacteric symptoms in a cohort of healthy perimenopausal women and also to evaluate the hormonal and biochemical profile of the subjects. Seventeen menopausal and 19 premenopausal women aged 40 years or more were interviewed and had venepuncture and collection of 24-h urine samples. Plasma from the blood samples was used for the assay of LH, FSH, progesterone, 17 beta-oestradiol, calcium and cholesterol while urinary calcium was determined from the 24-h urine samples. The data revealed a significant difference in the prevalence of the symptoms of vasomotor instability (hot flushes, palpitations and excessive sweating) among the menopausal group when compared with the premenopausal group. Furthermore, plasma gonadotrophin levels (LH and FSH) were significantly elevated while plasma oestradiol and progesterone levels were lower in the menopausal women than in the premenopausal group. With regards to the biochemical indices evaluated, only 24-h urinary calcium levels were found to be significantly different for the two groups, with higher levels in the menopausal women. The significance of these findings and the need for adequate screening and treatment of selected menopausal women are discussed. IS - 4 JF - African journal of medicine and medical sciences SN - 0309-3913 EP - 255 TI - Clinical, hormonal and biochemical features of menopausal women in Ibadan, Nigeria. VL - 18 SP - 251 KW - estrogen KW - hormone KW - measurement KW - menopausal KW - nigeria KW - profile AU - Otolorin, EO AU - Adeyefa, I AU - Osotimehin, BO AU - Fatinikun, T AU - Ojengbede, O AU - Otubu, JO AU - Ladipo, OA PY - 1989/12// UR - http://view.ncbi.nlm.nih.gov/pubmed/2558555 ER -