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We review recent progress in modeling the structures, binding affinities, and binding rates of protein–protein and protein–nucleic acid complexes. Limitations and promises of a wide range of computational approaches are presented.
@article{citeulike:4067261, abstract = {We review recent progress in modeling the structures, binding affinities, and binding rates of protein–protein and protein–nucleic acid complexes. Limitations and promises of a wide range of computational approaches are presented.}, author = {Zhou, H. and Qin, S. and Tjong, H.}, citeulike-article-id = {4067261}, citeulike-linkout-0 = {http://dx.doi.org/10.1016/S1574-1400(08)00004-2}, citeulike-linkout-1 = {http://linkinghub.elsevier.com/retrieve/pii/S1574140008000042}, doi = {10.1016/S1574-1400(08)00004-2}, issn = {15741400}, journal = {Annual Reports in Computational Chemistry}, keywords = {dna, modeling, molecular\_dynamics, protein}, pages = {67--87}, posted-at = {2009-10-06 11:31:19}, priority = {2}, title = {Chapter 4 Modeling Protein–Protein and Protein–Nucleic Acid Interactions: Structure, Thermodynamics, and Kinetics}, url = {http://dx.doi.org/10.1016/S1574-1400(08)00004-2}, volume = {4}, year = {2008} }
TY - JOUR ID - citeulike:4067261 L3 - citeulike-article-id:4067261 N2 - We review recent progress in modeling the structures, binding affinities, and binding rates of protein–protein and protein–nucleic acid complexes. Limitations and promises of a wide range of computational approaches are presented. JF - Annual Reports in Computational Chemistry SN - 15741400 EP - 87 TI - Chapter 4 Modeling Protein–Protein and Protein–Nucleic Acid Interactions: Structure, Thermodynamics, and Kinetics VL - 4 SP - 67 KW - dna KW - modeling KW - molecular_dynamics KW - protein AU - Zhou, H AU - Qin, S AU - Tjong, H PY - 2008/// UR - http://dx.doi.org/10.1016/S1574-1400(08)00004-2 ER -