Duplication and Selection on Abalone Sperm Lysin in an Allopatric Population Export

@article{citeulike:1616099, abstract = {While gene duplication is a major source of evolutionary novelty, the importance of this process in reproductive protein evolution has not been widely investigated. Here, we report the first known case of gene duplication of abalone sperm lysin in an allopatric subspecies found in the Eastern Atlantic, Haliotis tuberculata coccinea. Mass spectrometry identified both copies of the lysin protein in testis tissue, and 3-dimensional structural modeling suggests that both proteins remain functional. We also detected positive selection acting on both paralogs after duplication and found evidence of a recent selective sweep. Because H. t. coccinea occurs in geographic isolation from other abalone species, these findings suggest that the evolution of lysin is not driven to create reproductive barriers to unfit hybrid formation with an overlapping species. Instead, sexual selection or sexual conflict acting during abalone fertilization could be responsible for the recent positive selection on this protein. The presence of multiple, rapidly evolving lysin genes in H. tuberculata presents an opportunity to study the early stages of diversification of a protein whose function is well understood. 10.1093/molbev/msm137}, author = {Clark, Nathaniel L. and Findlay, Geoffrey D. and Yi, Xianhua and Maccoss, Michael J. and Swanson, Willie J.}, citeulike-article-id = {1616099}, citeulike-linkout-0 = {http://dx.doi.org/10.1093/molbev/msm137}, citeulike-linkout-1 = {http://mbe.oxfordjournals.org/cgi/content/abstract/24/9/2081}, citeulike-linkout-2 = {http://view.ncbi.nlm.nih.gov/pubmed/17630281}, citeulike-linkout-3 = {http://www.hubmed.org/display.cgi?uids=17630281}, day = {1}, doi = {10.1093/molbev/msm137}, journal = {Mol Biol Evol}, keywords = {abalone, adaptive-evolution, sperm-egg-binding, sperm-egg-recognition}, month = {September}, number = {9}, pages = {2081--2090}, posted-at = {2007-09-03 12:47:44}, priority = {2}, title = {Duplication and Selection on Abalone Sperm Lysin in an Allopatric Population}, url = {http://dx.doi.org/10.1093/molbev/msm137}, volume = {24}, year = {2007} }

TY - JOUR ID - citeulike:1616099 L3 - citeulike-article-id:1616099 N2 - While gene duplication is a major source of evolutionary novelty, the importance of this process in reproductive protein evolution has not been widely investigated. Here, we report the first known case of gene duplication of abalone sperm lysin in an allopatric subspecies found in the Eastern Atlantic, Haliotis tuberculata coccinea. Mass spectrometry identified both copies of the lysin protein in testis tissue, and 3-dimensional structural modeling suggests that both proteins remain functional. We also detected positive selection acting on both paralogs after duplication and found evidence of a recent selective sweep. Because H. t. coccinea occurs in geographic isolation from other abalone species, these findings suggest that the evolution of lysin is not driven to create reproductive barriers to unfit hybrid formation with an overlapping species. Instead, sexual selection or sexual conflict acting during abalone fertilization could be responsible for the recent positive selection on this protein. The presence of multiple, rapidly evolving lysin genes in H. tuberculata presents an opportunity to study the early stages of diversification of a protein whose function is well understood. 10.1093/molbev/msm137 IS - 9 JF - Mol Biol Evol EP - 2090 TI - Duplication and Selection on Abalone Sperm Lysin in an Allopatric Population VL - 24 SP - 2081 KW - abalone KW - adaptive-evolution KW - sperm-egg-binding KW - sperm-egg-recognition AU - Clark, Nathaniel AU - Findlay, Geoffrey AU - Yi, Xianhua AU - Maccoss, Michael AU - Swanson, Willie PY - 2007/09/01/ UR - http://dx.doi.org/10.1093/molbev/msm137 ER -