A computed tomography (CT) division can be viewed as a business subsidiary of a larger corporation--the radiology department. While a large amount of radiologic literature has been devoted to specific CT techniques and applications, there has been less of a focus on the operational structure required to achieve quality and efficiency in a CT division. This report includes discussion of the managerial structure, equipment purchases, continuing education, protocols, billing, and quality assurance measures that can be used to administer a CT division. 10.1148/radiol.2222010426