Multimodality Assessment of Esophageal Cancer: Preoperative Staging and Monitoring of Response to Therapy1 Export

@article{citeulike:5735003, abstract = {10.1148/rg.292085106 Esophageal cancer is a leading cause of cancer mortality worldwide. Complete resection of esophageal cancer and adjacent malignant lymph nodes is the only potentially curative treatment. Accurate preoperative staging and assessment of therapeutic response after neoadjuvant therapy are crucial in determining the most suitable therapy and avoiding inappropriate attempts at curative surgery. Computed tomography (CT) is recommended for initial imaging following confirmation of malignancy at pathologic analysis, primarily to rule out unresectable or distant metastatic disease. With the advent of multidetector CT, use of thin sections and multiplanar reformation allows more accurate staging of esophageal cancer. Endoscopic ultrasonography (US) is the best modality for determining the depth of tumor invasion and presence of regional lymph node involvement. Combined use of fine-needle aspiration and endoscopic US can improve assessment of lymph node involvement. Positron emission tomography (PET) is useful for assessment of distant metastases but is not appropriate for detecting and staging primary tumors. PET may also be helpful in restaging after neoadjuvant therapy, since it allows identification of early response to treatment and detection of interval distant metastases. Each imaging modality has its advantages and disadvantages; therefore, CT, endoscopic US, and PET should be considered complementary modalities for preoperative staging and therapeutic monitoring of patients with esophageal cancer. {\copyright} RSNA, 2009}, author = {Kim, Tae J. and Kim, Hyae Y. and Lee, Kyung W. and Kim, Moon S.}, citeulike-article-id = {5735003}, citeulike-linkout-0 = {http://dx.doi.org/10.1148/rg.292085106}, citeulike-linkout-1 = {http://radiographics.rsnajnls.org/content/29/2/403.abstract}, citeulike-linkout-2 = {http://radiographics.rsnajnls.org/content/29/2/403.full.pdf}, citeulike-linkout-3 = {http://view.ncbi.nlm.nih.gov/pubmed/19325056}, citeulike-linkout-4 = {http://www.hubmed.org/display.cgi?uids=19325056}, doi = {10.1148/rg.292085106}, journal = {Radiographics}, keywords = {cancer, carcinoma, oesophagus}, month = {March}, number = {2}, pages = {403--421}, posted-at = {2009-09-07 14:56:25}, priority = {0}, title = {Multimodality Assessment of Esophageal Cancer: Preoperative Staging and Monitoring of Response to Therapy1}, url = {http://dx.doi.org/10.1148/rg.292085106}, volume = {29}, year = {2009} }

TY - JOUR ID - citeulike:5735003 L3 - citeulike-article-id:5735003 N2 - 10.1148/rg.292085106 Esophageal cancer is a leading cause of cancer mortality worldwide. Complete resection of esophageal cancer and adjacent malignant lymph nodes is the only potentially curative treatment. Accurate preoperative staging and assessment of therapeutic response after neoadjuvant therapy are crucial in determining the most suitable therapy and avoiding inappropriate attempts at curative surgery. Computed tomography (CT) is recommended for initial imaging following confirmation of malignancy at pathologic analysis, primarily to rule out unresectable or distant metastatic disease. With the advent of multidetector CT, use of thin sections and multiplanar reformation allows more accurate staging of esophageal cancer. Endoscopic ultrasonography (US) is the best modality for determining the depth of tumor invasion and presence of regional lymph node involvement. Combined use of fine-needle aspiration and endoscopic US can improve assessment of lymph node involvement. Positron emission tomography (PET) is useful for assessment of distant metastases but is not appropriate for detecting and staging primary tumors. PET may also be helpful in restaging after neoadjuvant therapy, since it allows identification of early response to treatment and detection of interval distant metastases. Each imaging modality has its advantages and disadvantages; therefore, CT, endoscopic US, and PET should be considered complementary modalities for preoperative staging and therapeutic monitoring of patients with esophageal cancer. © RSNA, 2009 IS - 2 JF - Radiographics EP - 421 TI - Multimodality Assessment of Esophageal Cancer: Preoperative Staging and Monitoring of Response to Therapy1 VL - 29 SP - 403 KW - cancer KW - carcinoma KW - oesophagus AU - Kim, Tae AU - Kim, Hyae AU - Lee, Kyung AU - Kim, Moon PY - 2009/03// UR - http://dx.doi.org/10.1148/rg.292085106 ER -