Differences in body composition and cardiovascular and Type 2 diabetes risk factors between migrant and British-born British Pakistani women Export

@article{citeulike:3255791, abstract = {There is a high prevalence of cardiovascular disease and Type 2 diabetes in people of South Asian origin living in affluent western countries. We do not know whether or how risk factors for these diseases change in subsequent generations born in the west. Findings that birth-weight is inversely associated with abdominal obesity and risk of cardiovascular disease and Type 2 diabetes in later life suggest that those born in the west may have lower levels of risk than migrants. We assessed 30 migrants from Pakistan to the UK, 30 British-born British Pakistani women, and 25 British-born women of European origin. British-born British Pakistani women were taller (P = 0.05), had a lower waist to hip ratio (P = 0.04), lower mean fasting glucose levels (P = 0.03), lower mean triglyceride levels (P = 0.03), and higher mean HDL levels (P \< 0.001) than migrant British Pakistani women. Levels of fasting insulin, HOMA-IR, and blood pressure were not significantly different in the two British Pakistani groups. Thus, we found healthier levels of several cardiovascular and Type 2 diabetes risk factors in British-born British Pakistani women than in migrant British Pakistani women. These findings might be related to the effects of early environment or to other factors, such as differences in health behaviors. British-born British Pakistani women also differed from British-born European women, having a more adverse body composition, but healthier levels of HDL cholesterol and blood pressure. Am. J. Hum. Biol., 2008. {\copyright} 2008 Wiley-Liss, Inc.}, address = {Medical Anthropology Research Group, Department of Anthropology, Durham University, Durham, DH1 3HN, United Kingdom; Institute of Health and Society, Newcastle University, Newcastle upon Tyne, NE2 4HH, United Kingdom; Information Services Division, NHS National Services, Edinburgh, EH12 9EB, United Kingdom}, author = {Pollard, Tessa M. and Unwin, Nigel and Fischbacher, Colin and Chamley, Jagdip K.}, citeulike-article-id = {3255791}, citeulike-linkout-0 = {http://dx.doi.org/10.1002/ajhb.20773}, citeulike-linkout-1 = {http://www3.interscience.wiley.com/cgi-bin/abstract/118859224/ABSTRACT}, doi = {10.1002/ajhb.20773}, journal = {American Journal of Human Biology}, keywords = {body-composition, developmental-plasticity, diabetes, migrants}, number = {5}, pages = {545--549}, posted-at = {2008-09-15 04:20:40}, priority = {3}, title = {Differences in body composition and cardiovascular and Type 2 diabetes risk factors between migrant and British-born British Pakistani women}, url = {http://dx.doi.org/10.1002/ajhb.20773}, volume = {20}, year = {2008} }

TY - JOUR ID - citeulike:3255791 L3 - citeulike-article-id:3255791 N2 - There is a high prevalence of cardiovascular disease and Type 2 diabetes in people of South Asian origin living in affluent western countries. We do not know whether or how risk factors for these diseases change in subsequent generations born in the west. Findings that birth-weight is inversely associated with abdominal obesity and risk of cardiovascular disease and Type 2 diabetes in later life suggest that those born in the west may have lower levels of risk than migrants. We assessed 30 migrants from Pakistan to the UK, 30 British-born British Pakistani women, and 25 British-born women of European origin. British-born British Pakistani women were taller (P = 0.05), had a lower waist to hip ratio (P = 0.04), lower mean fasting glucose levels (P = 0.03), lower mean triglyceride levels (P = 0.03), and higher mean HDL levels (P < 0.001) than migrant British Pakistani women. Levels of fasting insulin, HOMA-IR, and blood pressure were not significantly different in the two British Pakistani groups. Thus, we found healthier levels of several cardiovascular and Type 2 diabetes risk factors in British-born British Pakistani women than in migrant British Pakistani women. These findings might be related to the effects of early environment or to other factors, such as differences in health behaviors. British-born British Pakistani women also differed from British-born European women, having a more adverse body composition, but healthier levels of HDL cholesterol and blood pressure. Am. J. Hum. Biol., 2008. © 2008 Wiley-Liss, Inc. IS - 5 JF - American Journal of Human Biology AD - Medical Anthropology Research Group, Department of Anthropology, Durham University, Durham, DH1 3HN, United Kingdom; Institute of Health and Society, Newcastle University, Newcastle upon Tyne, NE2 4HH, United Kingdom; Information Services Division, NHS National Services, Edinburgh, EH12 9EB, United Kingdom EP - 549 TI - Differences in body composition and cardiovascular and Type 2 diabetes risk factors between migrant and British-born British Pakistani women VL - 20 SP - 545 KW - body-composition KW - developmental-plasticity KW - diabetes KW - migrants AU - Pollard, Tessa AU - Unwin, Nigel AU - Fischbacher, Colin AU - Chamley, Jagdip PY - 2008/// UR - http://dx.doi.org/10.1002/ajhb.20773 ER -