carlosjavierna's profile

Recent Activity

• 18:13: posted The Discodermolide Hairpin Structure Flows from Conformationally Stable Modular Motifs

• 16:56: posted Gly-Gly-Containing Triplets of Low Stability Adjacent to a Type III Collagen Epitope†
• 15:04: posted Gas-Phase Hydrogen/Deuterium Exchange in a Traveling Wave Ion Guide for the Examination of Protein Conformations
• 15:03: posted Direct Optical Detection of Aptamer Conformational Changes Induced by Target Molecules
• 14:57: posted A short disordered N-terminal flagellin segment is a fully functional flagellar type III export signal. Application for secreted protein expression
• 14:56: posted The Discovery of Z-DNA: the Work of Alexander Rich
• 14:51: posted Abnormal Expression of Collagen IV in Lens Activates Unfolded Protein Response Resulting in Cataract
• 14:47: posted The Divalent Metal Transporter Homologues SMF-1/2 Mediate Dopamine Neuron Sensitivity in Caenorhabditis elegans Models of Manganism and Parkinson Disease
• 14:44: posted A Common Mutation in Paraoxonase-2 Results in Impaired Lactonase Activity
• 14:42: posted Signal Transducer and Activator of Transcription 3 (STAT3) Mediates Amino Acid Inhibition of Insulin Signaling through Serine 727 Phosphorylation
• 14:40: posted Allosteric Inhibition of Human Porphobilinogen Synthase
• 14:39: posted Crystal Structure and Functional Analysis of Homocitrate Synthase, an Essential Enzyme in Lysine Biosynthesis
• 14:34: posted The Lysine 48 and Lysine 63 Ubiquitin Conjugates Are Processed Differently by the 26 S Proteasome
• 14:29: posted Regulation of Cellular Protein Phosphatase-1 (PP1) by Phosphorylation of the CPI-17 Family, C-kinase-activated PP1 Inhibitors

• 07:00: posted Pattern recognition receptors require N-glycosylation to mediate plant immunity
• 05:32: posted Dephosphorylation of {gamma}H2A by Glc7/Protein Phosphatase 1 Promotes Recovery from Inhibition of DNA Replication
• 05:29: posted Fluorescence Resonance Energy Transfer Analysis of Merlin Conformational Changes
• 04:53: posted A large intrinsically disordered region in SKIP and its disorder-order transition induced by PPIL1 binding revealed by NMR
• 03:36: posted Conformational Properties of Unfolded HypF-N
• 03:10: posted Effects of a Mutation on the Folding Mechanism of a β-Hairpin
• 00:49: posted Conformational Effects of the Non-natural α-Methylserine on Small Peptides and Glycopeptides

• 14:16: posted Amino acid residues critical for endoplasmic reticulum export and recycling of platelet-activating factor receptor
• 14:13: posted A network of hydrogen bonds on the surface of TLR2 controls ligand positioning and cell signaling
• 14:08: posted Catalytic role of the metal ION in the metallo-β-lactamase GOB

• 02:09: posted A fast and accurate method for predicting pKa of residues in proteins
• 01:58: posted Universal function-specificity of codon usage.
• 00:51: posted Quantitative Description of Backbone Conformational Sampling of Unfolded Proteins at Amino Acid Resolution from NMR Residual Dipolar Couplings
• 00:46: posted Urea Destabilizes RNA by Forming Stacking Interactions and Multiple Hydrogen Bonds with Nucleic Acid Bases

• 19:50: posted The Multifaceted Photocytotoxic Profile of Hypericin
• 19:50: posted Scientific and Regulatory Perspectives on Metabolizing Enzyme−Transporter Interplay and Its Role in Drug Interactions: Challenges in Predicting Drug Interactions†
• 19:49: posted Interplay of Transporters and Enzymes in Drug and Metabolite Processing
• 19:48: posted The Drug Transporter−Metabolism Alliance: Uncovering and Defining the Interplay
• 19:48: posted Hepatic OATP1B Transporters and Nuclear Receptors PXR and CAR: Interplay, Regulation of Drug Disposition Genes, and Single Nucleotide Polymorphisms
• 19:48: posted Impact of Hepatic Uptake Transporters on Pharmacokinetics and Drug−Drug Interactions: Use of Assays and Models for Decision Making in the Pharmaceutical Industry

• 03:00: posted Properties Calculations of Silica-Based Glasses by Atomistic Simulations Techniques: A Review