dchughes's profile

Recent Activity

• 16:54: posted Buccal DNA collection: comparison of buccal swabs with FTA cards.

• 16:01: posted Strategies for microsatellite isolation: a review.
• 16:00: posted Targeted oligonucleotide-mediated microsatellite identification (TOMMI) from large-insert library clones.
• 11:12: posted Versatile screening for binary protein-protein interactions by yeast two-hybrid mating.

• 13:04: posted Phylogeography of the human mitochondrial haplogroup L3e: a snapshot of African prehistory and Atlantic slave trade.
• 10:28: posted BBC NEWS | Science/Nature | Ancient bones could yield TB clue
• 10:27: posted BBC NEWS | Health | Breastfeeding trust hormone clue

• 10:16: posted Life after SuperBabe
• 10:16: posted Mitochondrial DNA population data of HV1 and HV2 sequences from Japanese individuals
• 10:13: posted Investigation of telomere lengths measurement by quantitative real-time PCR to predict age

• 15:53: posted Genome-wide analysis of histone modifications by ChIP-on-chip.
• 09:38: posted Usher syndromes due to MYO7A, PCDH15, USH2A or GPR98 mutations share retinal disease mechanism

• 16:36: posted The Deep Archaeal Roots of Eukaryotes
• 14:54: posted Comparative genomics reveals gene-specific and shared regulatory sequences in the spermatid-expressed mammalian Odf1, Prm1, Prm2, Tnp1, and Tnp2 genes
• 14:52: posted UCSC genome browser tutorial.
• 13:34: posted The Sperm Proteins from Amphioxus Mirror Its Basal Position among Chordates and Redefine the Origin of Vertebrate Protamines

• 14:36: posted Just the FACTs: Histone H2B Ubiquitylation and Nucleosome Dynamics
• 14:21: posted Evo-Devo and an Expanding Evolutionary Synthesis: A Genetic Theory of Morphological Evolution

• 13:01: posted Genomic organisation and alternative splicing of human RIM1, a gene implicated in autosomal dominant cone-rod dystrophy (CORD7).
• 12:52: posted The mouse neurological mutant flailer expresses a novel hybrid gene derived by exon shuffling between Gnb5 and Myo5a.

• 16:22: posted Regulation of rod phototransduction machinery by ciliary neurotrophic factor.

• 14:02: posted Phylogenetic Signal in the Eukaryotic Tree of Life
• 13:36: posted The amphioxus genome illuminates vertebrate origins and cephalochordate biology
• 13:36: posted Extensive variation between inbred mouse strains due to endogenous L1 retrotransposition
• 13:33: posted A protocol for constructing gene targeting vectors: generating knockout mice for the cadherin family and beyond
• 13:12: posted Translation from nonautonomous type IAP retrotransposon is a critical determinant of transposition activity: Implication for retrotransposon-mediated genome evolution
• 13:02: posted The new paradigm of flow cell sequencing
• 13:01: posted Identification and analysis of ancestral hominoid transcriptome inferred from cross-species transcript and processed pseudogene comparisons
• 12:52: posted Two strategies for gene regulation by promoter nucleosomes
• 12:49: posted The biological effects of simple tandem repeats: Lessons from the repeat expansion diseases
• 12:45: posted The mouse A/HeJ Y chromosome: Another good Y gone bad
• 12:34: posted Target mRNAs are repressed as efficiently by microRNA-binding sites in the 5' UTR as in the 3' UTR.
• 12:30: posted A rapid micro chromatin immunoprecipitation assay (ChIP)
• 12:26: posted Production of neurons, astrocytes and oligodendrocytes from mammalian CNS stem cells

• 15:00: posted Endosomal trafficking of Src tyrosine kinase
• 14:58: posted The meaning of nonsense
• 14:10: posted Growth arrest specific protein 6/Axl signaling in human inflammatory renal diseases.

• 13:43: posted RPGR is mutated in patients with a complex X linked phenotype combining primary ciliary dyskinesia and retinitis pigmentosa.
• 13:42: posted Overexpression of RPGR Leads to Male Infertility in Mice Due to Defects in Flagellar Assembly.
• 13:28: posted Synaptopodin-deficient mice lack a spine apparatus and show deficits in synaptic plasticity.
• 13:26: posted Dendritic spines and long-term plasticity
• 11:57: posted A Phylogenomic Study of Birds Reveals Their Evolutionary History
• 11:55: posted Proliferating Cells Express mRNAs with Shortened 3' Untranslated Regions and Fewer MicroRNA Target Sites
• 11:53: posted CELL BIOLOGY: Arrestin' Movement in Cilia.
• 11:49: posted A novel gene that encodes a protein with a putative src homology 3 domain is a candidate gene for familial juvenile nephronophthisis.
• 11:47: posted BIOCHEMISTRY: How Do Proteins Interact?
• 11:25: posted A novel gene encoding an SH3 domain protein is mutated in nephronophthisis type 1.
• 11:16: posted Genomic analysis of mouse retinal development.

• 16:00: posted Polymorphisms in the CNTF and CNTF receptor genes are associated with muscle strength in men and women.
• 15:57: posted Structural and functional abnormalities of retinal ribbon synapses due to Cacna2d4 mutation.
• 13:12: posted BBC NEWS | England | Kent | Baby girl born after bus adverts
• 12:09: posted VEGFR-3 expression is restricted to blood and lymphatic vessels in solid tumors.
• 12:04: posted Catechol-o-methyltransferase gene polymorphism is associated with skeletal muscle properties in older women alone and together with physical activity.

• 17:03: posted Mouse segmental duplication and copy number variation
• 12:36: posted The Platypus Genome Unraveled
• 11:06: posted Evolution of Mammals and Their Gut Microbes
• 11:00: posted The human retinitis pigmentosa GTPase regulator gene variant database.

• 14:24: posted Mutations in the gene coding for guanylate cyclase-activating protein 2 (GUCA1B gene) in patients with autosomal dominant retinal dystrophies.
• 14:15: posted Mutation in the auxiliary calcium-channel subunit CACNA2D4 causes autosomal recessive cone dystrophy.

• 15:49: posted Vasopressin V2 receptor expression along rat, mouse, and human renal epithelia with focus on TAL.