Sat, 26 Jul 2008 04:41:48 BST CiteULike: AlfonsoVicenteSuarez's Pflanz http://www.citeulike.org/user/AlfonsoVicenteSuarez/author/Pflanz CiteULike.org en-gb Copyright © 2004-2008 citeulike.org http://www.citeulike.org/user/AlfonsoVicenteSuarez/article/1387797 <i>Immunity, Vol. 19, No. 5. (November 2003), pp. 641-644.</i><br /><br />Originally the only known heterodimeric cytokine, IL-12 is now part of a family of five cytokines and shares important functions in the regulation of both innate and adaptive immunity with two of them, IL-23 and IL-27. Although initially these three cytokines were considered to have largely overlapping immunological functions, more recent studies, including two articles in this issue of Immunity ( and ), indicate that they mediate complex and well-differentiated functions. The IL-12 Family of Heterodimeric Cytokines: New Players in the Regulation of T Cell Responses Giorgio Trinchieri Stefan Pflanz Robert Kastelein Immunity, Vol. 19, No. 5. (November 2003), pp. 641-644. 2007-06-13T16:42:37-00:00 2003 Immunity 19 5 641 644 il-12-general