Thu, 21 Aug 2008 15:30:21 BST CiteULike: alivetec's Capurro http://www.citeulike.org/user/alivetec/author/Capurro CiteULike.org en-gb Copyright © 2004-2008 citeulike.org http://www.citeulike.org/user/alivetec/article/1185594 <i>Physica A: Statistical Mechanics and its Applications, Vol. 378, No. 2. (15 May 2007), pp. 336-344.</i><br /><br />We have analyzed simultaneous recordings of respiration and heartbeat intervals in diabetic patients and control subjects. Our main findings are that in diabetic patients the heart beat-to-beat interval variability and cardiorespiratory crosscorrelation are decreased, the autocorrelation time of the interval series is increased, and the phase relation of the respiration with the heartbeat interval oscillations is often reversed in comparison with the control subjects. We have been able to reproduce the data using a biophysical model in which the time dependent input signal to the sinoatrial node was constituted of quasiperiodic and aperiodic components. The quasiperiodic input was obtained from the recording of the respiratory signal and the aperiodic input was obtained from selected realizations of correlated noise. Our study indicates that both input components to the sinoatrial node are modified in diabetic patients. Respiratory modulation of heart beat-to-beat interval in diabetic patients Alberto Capurro Coraci Malta Luis Diambra Paola Contreras Eduardo Migliaro doi:10.1016/j.physa.2006.11.081 Physica A: Statistical Mechanics and its Applications, Vol. 378, No. 2. (15 May 2007), pp. 336-344. 2007-03-24T22:20:19-00:00 2007 Physica A: Statistical Mechanics and its Applications 378 2 336 344 no-tag