CiteULike: brembs's library [24 articles] http://www.citeulike.org/user/brembs/order/to_read CiteULike.org en-gb Copyright © 2004-2008 citeulike.org http://www.citeulike.org/user/brembs/article/494350 <i>Curr Opin Neurobiol, Vol. 15, No. 6. (December 2005), pp. 638-644.</i><br /><br />The field of basal ganglia research is exploding on every level - from discoveries at the molecular level to those based on human brain imaging. A remarkable series of new findings support the view that the basal ganglia are essential for some forms of learning-related plasticity. Other new findings are challenging some of the basic tenets of the field as it now stands. Combined with the new evidence on learning-related functions of the basal ganglia, these studies suggest that the basal ganglia are parts of a brain-wide set of adaptive neural systems promoting optimal motor and cognitive control. The basal ganglia: learning new tricks and loving it. AM Graybiel doi:10.1016/j.conb.2005.10.006 Curr Opin Neurobiol, Vol. 15, No. 6. (December 2005), pp. 638-644. 2006-02-06T19:49:44-00:00 Curr Opin Neurobiol 0959-4388 15 6 638 644 no-tag http://www.citeulike.org/user/brembs/article/2307582 <i>Current Biology, Vol. 18, No. 2. (22 January 2008), pp. R60-R62.</i><br /><br />Summary Numerical and spatial cognition rely on common functional circuits in the parietal lobes of the brain [1]. While previous work has established that the mere perception of numbers can bias a subject's attention in space [2], the method of random digit generation has only recently been introduced to a rapidly growing literature exploring asymmetries in number space [3]. Here we show that human subjects' attempts to generate numbers `at random' are systematically influenced by lateral head turns, which are known to reallocate spatial attention in the outside world. Specifically, while facing left, subjects produced relatively small numbers, whereas while facing right they tended to produce larger numbers. These results support current concepts of parietal cortex as mediating the interplay between spatial attention and abstract thought [4]. Head turns bias the brain's internal random generator Tobias Loetscher Urs Schwarz Michele Schubiger Peter Brugger doi:10.1016/j.cub.2007.11.015 Current Biology, Vol. 18, No. 2. (22 January 2008), pp. R60-R62. 2008-01-30T14:47:28-00:00 Current Biology 18 2 R60 R62 numbers random spontaneous http://www.citeulike.org/user/brembs/article/1206070 <i>Trends in Neurosciences, Vol. In Press, Corrected Proof</i><br /><br />There are several brain regions that have been implicated in the control of motivated behavior and whose disruption leads to the pathophysiology observed in major psychiatric disorders. These systems include the ventral hippocampus, which is involved in context and focus on tasks, the amygdala, which mediates emotional behavior, and the prefrontal cortex, which modulates activity throughout the limbic system to enable behavioral flexibility. Each of these systems has overlapping projections to the nucleus accumbens, where these inputs are integrated under the modulatory influence of dopamine. Here, we provide a systems-oriented approach to interpreting the function of the dopamine system, its modulation of limbic-cortical interactions and how disruptions within this system might underlie the pathophysiology of schizophrenia and drug abuse. Regulation of firing of dopaminergic neurons and control of goal-directed behaviors Anthony Grace Stan Floresco Yukiori Goto Daniel Lodge doi:10.1016/j.tins.2007.03.003 Trends in Neurosciences, Vol. In Press, Corrected Proof 2007-04-04T14:05:09-00:00 Trends in Neurosciences In Press, Corrected Proof behavior decision-making habit instrumental learning neurobiology neuroscience operant psychology http://www.citeulike.org/user/brembs/article/1023152 <i>Cell, Vol. 127, No. 7. (29 December 2006), pp. 1453-1467.</i><br /><br />SummaryMolecular analyses of Aplysia, a well-established model organism for cellular and systems neural science, have been seriously handicapped by a lack of adequate genomic information. By sequencing cDNA libraries from the central nervous system (CNS), we have identified over 175,000 expressed sequence tags (ESTs), of which 19,814 are unique neuronal gene products and represent 50%-70% of the total Aplysia neuronal transcriptome. We have characterized the transcriptome at three levels: (1) the central nervous system, (2) the elementary components of a simple behavior: the gill-withdrawal reflex--by analyzing sensory, motor, and serotonergic modulatory neurons, and (3) processes of individual neurons. In addition to increasing the amount of available gene sequences of Aplysia by two orders of magnitude, this collection represents the largest database available for any member of the Lophotrochozoa and therefore provides additional insights into evolutionary strategies used by this highly successful diversified lineage, one of the three proposed superclades of bilateral animals. Neuronal Transcriptome of Aplysia: Neuronal Compartments and Circuitry Leonid Moroz John Edwards Sathyanarayanan Puthanveettil Andrea Kohn Thomas Ha Andreas Heyland Bjarne Knudsen Anuj Sahni Fahong Yu Li Liu doi:10.1016/j.cell.2006.09.052 Cell, Vol. 127, No. 7. (29 December 2006), pp. 1453-1467. 2007-01-03T10:18:42-00:00 Cell 127 7 1453 1467 aplysia classical conditioning instrumental invertebrate neurobiology neuroscience operant pavlovian http://www.citeulike.org/user/brembs/article/2773606 <i>Science (8 May 2008), 1154456.</i><br /><br />We question whether homeostasis alone adequately explains microbial responses to environmental stimuli, and explore the capacity of intra-cellular networks for predictive behavior in a fashion similar to metazoan nervous systems. We show that in silico biochemical networks, evolving randomly under precisely defined complex habitats, capture the dynamical, multi-dimensional structure of diverse environments by forming internal models that allow prediction of environmental change. We provide evidence for such anticipatory behavior by revealing striking correlations of Escherichia coli transcriptional responses to temperature and oxygen perturbations--precisely mirroring the co-variation of these parameters upon transitions between the outside world and the mammalian gastrointestinal-tract. We further show that these internal correlations reflect a true associative learning paradigm, since they show rapid de-coupling upon exposure to novel environments. 10.1126/science.1154456 Anticipatory Behavior Within Microbial Genetic Networks Ilias Tagkopoulos Yir-Chung Liu Saeed Tavazoie doi:10.1126/science.1154456 Science (8 May 2008), 1154456. 2008-05-08T21:24:02-00:00 Science 1154456 degeneracy http://www.citeulike.org/user/brembs/article/80546 <i>PLoS One, Vol. 2, No. 5. (May 2007), e443.</i> Order in spontaneous behavior Alexander Maye Chih-Hao Hsieh George Sugihara Björn Brembs PLoS One, Vol. 2, No. 5. (May 2007), e443. 2005-01-20T00:29:54-00:00 PLoS One 2 5 e443 behavior decision-making drosophila flies invertebrate neurobiology neuroscience predator-avoidance psychology