Thu, 21 Aug 2008 09:47:34 BST CiteULike: jyuh's Rudolph http://www.citeulike.org/user/jyuh/author/Rudolph CiteULike.org en-gb Copyright © 2004-2008 citeulike.org http://www.citeulike.org/user/jyuh/article/2891250 <i>Computer methods and programs in biomedicine (7 June 2008)</i><br /><br />This paper describes the open source framework MARVIN for rapid application development in the field of biomedical and clinical research. MARVIN applications consist of modules that can be plugged together in order to provide the functionality required for a specific experimental scenario. Application modules work on a common patient database that is used to store and organize medical data as well as derived data. MARVIN provides a flexible input/output system with support for many file formats including DICOM, various 2D image formats and surface mesh data. Furthermore, it implements an advanced visualization system and interfaces to a wide range of 3D tracking hardware. Since it uses only highly portable libraries, MARVIN applications run on Unix/Linux, Mac OS X and Microsoft Windows. MARVIN: a medical research application framework based on open source software. Tobias Rudolph Marc Puls Christoph Anderegg Lars Ebert Martina Broehan Adrian Rudin Jens Kowal doi:10.1016/j.cmpb.2008.04.007 Computer methods and programs in biomedicine (7 June 2008) 2008-06-13T12:13:57-00:00 2008 Computer methods and programs in biomedicine 0169-2607 ai http://www.citeulike.org/user/jyuh/article/2806280 <i>Gastroenterology, Vol. 134, No. 6. (May 2008), pp. 1752-1763.</i><br /><br />The diagnosis and treatment of hepatocellular carcinoma (HCC) have witnessed major changes over the past decade. Until the early 1990s, HCC was a relatively rare malignancy, typically diagnosed at an advanced stage in a symptomatic patient, and there were no known effective palliative or therapeutic options. However, the rising incidence of HCC in several regions around the world coupled with emerging evidence for efficacy of screening in high-risk patients, liver transplantation as a curative option in select patients, ability to make definitive diagnosis using high-resolution imaging of the liver, less dependency on obtaining tissue diagnosis, and proven efficacy of transarterial chemoembolization and sorafenib as palliative therapy have improved the outlook for HCC patients. In this article, we present a summary of the most recent information on screening, diagnosis, staging, and different treatment modalities of HCC, as well as our recommended management approach. Diagnosis and Treatment of Hepatocellular Carcinoma Hashem El-Serag Jorge Marrero Lenhard Rudolph Rajender Reddy doi:10.1053/j.gastro.2008.02.090 Gastroenterology, Vol. 134, No. 6. (May 2008), pp. 1752-1763. 2008-05-17T03:14:47-00:00 2008 Gastroenterology 134 6 1752 1763 hcc http://www.citeulike.org/user/jyuh/article/2724083 <i>Gastroenterology, Vol. 134, No. 3. (March 2008), pp. 875-878.</i> Rho GTPase and Wnt signaling pathways in hepatocarcinogenesis. A Lechel KL Rudolph doi:10.1053/j.gastro.2008.01.055 Gastroenterology, Vol. 134, No. 3. (March 2008), pp. 875-878. 2008-04-27T15:12:50-00:00 2008 Gastroenterology 1528-0012 134 3 875 878 no-tag