Thu, 21 Aug 2008 00:45:13 BST CiteULike: margaritis's networks http://www.citeulike.org/user/margaritis/tag/networks CiteULike.org en-gb Copyright © 2004-2008 citeulike.org http://www.citeulike.org/user/margaritis/article/2739852 <i>Nature, Vol. 453, No. 7191., pp. 98-101.</i> Hierarchical structure and the prediction of missing links in networks Aaron Clauset Cristopher Moore MEJ Newman doi:10.1038/nature06830 Nature, Vol. 453, No. 7191., pp. 98-101. 2008-04-30T19:31:59-00:00 Nature 0028-0836 453 7191 98 101 Nature Publishing Group complexity hierarchical networks http://www.citeulike.org/user/margaritis/article/1059761 <i>Science, Vol. 315, No. 5810. (19 January 2007), pp. 370-373.</i><br /><br />Cells both actively generate and sensitively react to forces through their mechanical framework, the cytoskeleton, which is a nonequilibrium composite material including polymers and motor proteins. We measured the dynamics and mechanical properties of a simple three-component model system consisting of myosin II, actin filaments, and cross-linkers. In this system, stresses arising from motor activity controlled the cytoskeletal network mechanics, increasing stiffness by a factor of nearly 100 and qualitatively changing the viscoelastic response of the network in an adenosine triphosphate-dependent manner. We present a quantitative theoretical model connecting the large-scale properties of this active gel to molecular force generation. Nonequilibrium mechanics of active cytoskeletal networks. D Mizuno C Tardin CF Schmidt FC Mackintosh doi:10.1126/science.1134404 Science, Vol. 315, No. 5810. (19 January 2007), pp. 370-373. 2007-01-22T13:22:28-00:00 2007 Science 1095-9203 315 5810 370 373 active networks