Thu, 21 Aug 2008 13:57:45 BST CiteULike: neils's Shokat http://www.citeulike.org/user/neils/author/Shokat CiteULike.org en-gb Copyright © 2004-2008 citeulike.org http://www.citeulike.org/user/neils/article/2054417 <i>Bioinformatics, Vol. 18, No. 9. (Sep 2002), pp. 1274-1275.</i><br /><br />SUMMARY: The Kinase Sequence Database (KSD) located at http://kinase.ucsf.edu/ksd contains information on 290 protein kinase families derived by profile-based clustering of the non-redundant list of sequences obtained from a GenBank-wide search. Included in the database are a total of 5,041 protein kinases from over 100 organisms. Clustering into families is based on the extent of homology within the kinase catalytic domain (250-300 residues in length). Alignments of the families are viewed by interactive Excel-based sequence spreadsheets. In addition, KSD features evolutionary trees derived for each family and detailed information on each sequence as well as links to the corresponding GenBank entries. Sequence manipulation tools, such as evolutionary tree generation, novel sequence assignment, and statistical analysis, are also provided. AVAILABILITY: The kinase sequence database is a web-based service accessible at http://kinase.ucsf.edu/ksd CONTACT: buzko@cmp.ucsf.edu; shokat@cmp.ucsf.edu/ksd A kinase sequence database: sequence alignments and family assignment. Oleksandr Buzko Kevan Shokat Bioinformatics, Vol. 18, No. 9. (Sep 2002), pp. 1274-1275. 2007-12-04T03:22:09-00:00 2002 Bioinformatics 18 9 1274 1275 alignment analysis article-predikin cluster database homology information internet kinase management protein retrieval sequence storage system http://www.citeulike.org/user/neils/article/2053686 <i>Bioinformatics, Vol. 18, No. 9. (2002), pp. 1274-1275.</i><br /><br />SUMMARY: The Kinase Sequence Database (KSD) located at http://kinase.ucsf.edu/ksd contains information on 290 protein kinase families derived by profile-based clustering of the non-redundant list of sequences obtained from a GenBank-wide search. Included in the database are a total of 5,041 protein kinases from over 100 organisms. Clustering into families is based on the extent of homology within the kinase catalytic domain (250-300 residues in length). Alignments of the families are viewed by interactive Excel-based sequence spreadsheets. In addition, KSD features evolutionary trees derived for each family and detailed information on each sequence as well as links to the corresponding GenBank entries. Sequence manipulation tools, such as evolutionary tree generation, novel sequence assignment, and statistical analysis, are also provided. AVAILABILITY: The kinase sequence database is a web-based service accessible at http://kinase.ucsf.edu/ksd CONTACT: buzko@cmp.ucsf.edu; shokat@cmp.ucsf.edu/ksd A kinase sequence database: sequence alignments and family assignment O Buzko KM Shokat Bioinformatics, Vol. 18, No. 9. (2002), pp. 1274-1275. 2007-12-04T01:53:36-00:00 2002 Bioinformatics 18 9 1274 1275 article-nar article-pka-pkg database kinase sequence