Sun, 27 Jul 2008 09:12:49 BST CiteULike: weeks's Sturm http://www.citeulike.org/user/weeks/author/Sturm CiteULike.org en-gb Copyright © 2004-2008 citeulike.org http://www.citeulike.org/user/weeks/article/2030059 <i>Science, Vol. 304, No. 5673. (14 May 2004), pp. 987-990.</i><br /><br />We report on a microfluidic particle-separation device that makes use of the asymmetric bifurcation of laminar flow around obstacles. A particle chooses its path deterministically on the basis of its size. All particles of a given size follow equivalent migration paths, leading to high resolution. The microspheres of 0.8, 0.9, and 1.0 micrometers that were used to characterize the device were sorted in 40seconds with a resolution of [~]10nanometers, which was better than the time and resolution of conventional flow techniques. Bacterial artificial chromosomes could be separated in 10 minutes with a resolution of [~]12%. 10.1126/science.1094567 Continuous Particle Separation Through Deterministic Lateral Displacement Lotien Huang Edward Cox Robert Austin James Sturm doi:10.1126/science.1094567 Science, Vol. 304, No. 5673. (14 May 2004), pp. 987-990. 2007-11-30T17:48:27-00:00 2004 Science 304 5673 987 990 colloids microfluidics