Tag cdk [148 articles] Export

Recent papers classified by the tag cdk.

	Selective cyclin-dependent kinase inhibitors discriminating between cell cycle and transcriptional kinases: future reality or utopia? [My Copy] Annals of the New York Academy of Sciences, Vol. 1171, No. 1. (August 2009), pp. 228-241. by Józefa Wesierska-Gadek, Vladimír Krystof posted to inhibitor cdk by guhjy on 2009-11-23 10:40:59 as
	miR-449a and miR-449b are direct transcriptional targets of E2F1 and negatively regulate pRbâE2F1 activity through a feedback loop by targeting CDK6 and CDC25A [My Copy] Genes & Development, Vol. 23, No. 20. (15 October 2009), pp. 2388-2393. by Xiaojing Yang, Min Feng, Xia Jiang, et al.Zhenlong Wu, Zhimei Li, Meiyee Aau, Qiang Yu posted to mir-449 microrna e2f cdk by heliopais to the group microRNA on 2009-10-15 17:51:37 as
	CDK/ERK-mediated phosphorylation of the human influenza A virus NS1 protein at threonine-215. [My Copy] Virology, Vol. 383, No. 1. (5 January 2009), pp. 6-11. by Benjamin G. Hale, Axel Knebel, Catherine H. Botting, et al.Caroline S. Galloway, Bernard L. Precious, David Jackson, Richard M. Elliott, Richard E. Randall posted to virus kinase erk cdk by renatomilani on 2009-10-05 20:26:42 as
	Cataloging Kinase Targets [My Copy] Sci. Signal., Vol. 2, No. 90. (29 September 2009), ec323. by L. Bryan Ray posted to phosphoproteome cdk by renatomilani on 2009-09-30 17:29:30 as
	Evolving Cell Signals [My Copy] Science, Vol. 325, No. 5948. (25 September 2009), pp. 1635-1636. by Mark O. Collins posted to mass-spec kinase evolution cdk by renatomilani on 2009-09-25 05:08:54 as along with 1 person jago
	Global Analysis of Cdk1 Substrate Phosphorylation Sites Provides Insights into Evolution [My Copy] Science, Vol. 325, No. 5948. (25 September 2009), pp. 1682-1686. by Liam J. Holt, Brian B. Tuch, Judit Villen, Alexander D. Johnson, Steven P. Gygi, David O. Morgan posted to phosphorylation kinase evolution cdk analysis by neils on 2009-09-25 00:17:38 as along with 5 people nzm brianb walshtp djkt jjray
	XMPP for cloud computing in bioinformatics supporting discovery and invocation of asynchronous web services [My Copy] BMC Bioinformatics, Vol. 10, No. 1. (2009), 279. by Johannes Wagener, Ola Spjuth, Egon Willighagen, Jarl Wikberg posted to xmpp wsdl wave tools soap cdk by CameronNeylon on 2009-09-09 21:08:55 as along with 11 people and 1 group operon dswan brianb vagoskar walshtp daforerog mchelen barriot nuin dullhunk druvus Bioinformatics
	Role of CDK/cyclin complexes in transcription and RNA splicing. [My Copy] Cellular signalling, Vol. 17, No. 9. (September 2005), pp. 1033-1051. by Pascal Loyer, Janeen H. Trembley, Robert Katona, Vincent J. Kidd, Jill M. Lahti posted to cdk by Blo on 2009-08-24 16:07:28 as
	Cyclin-dependent kinases regulate the antiproliferative function of Smads [My Copy] Nature, Vol. 430, No. 6996. (8 July 2004), pp. 226-231. by Isao Matsuura, Natalia G. Denissova, Guannan Wang, Dongming He, Jianyin Long, Fang Liu posted to cdk cyclin-d1 smad by guhjy on 2009-08-04 16:29:34 as along with 2 people catcremona sennoma
	Global control of cell-cycle transcription by coupled CDK and network oscillators. [My Copy] Nature, Vol. 453, No. 7197. (12 June 2008), pp. 944-947. by David A. Orlando, Charles Y. Lin, Allister Bernard, et al.Jean Y. Wang, Joshua E. Socolar, Edwin S. Iversen, Alexander J. Hartemink, Steven B. Haase posted to cdk cell-cycle by guhjy on 2009-08-02 13:34:46 as along with 4 people and 1 group NicolSiegel jasonpark1 akastrin Petersarkies BP205
	Cell cycle kinases as therapeutic targets for cancer [My Copy] Nat Rev Drug Discov, Vol. 8, No. 7. (01 July 2009), pp. 547-566. by Silvia Lapenna, Antonio Giordano posted to cancer cdk cell-cycle by guhjy on 2009-07-31 11:39:41 as along with 3 people kokphinchooi sschurer reyez
	Dual role of CDKs in DNA repair: to be, or not to be. [My Copy] DNA repair, Vol. 8, No. 1. (1 January 2009), pp. 6-18. by Keiko Yata, Fumiko Esashi posted to cdk cell-cycle dna-damage by guhjy on 2009-07-31 11:37:48 as along with 1 person catcremona
	Cyclin-dependent kinase inhibitors as potential targeted anticancer agents. [My Copy] Investigational new drugs (5 March 2009) by Ivan Diaz-Padilla, Lillian L. Siu, Ignacio Duran posted to cancer cdk inhibitor by guhjy on 2009-07-11 14:14:37 as
	Cell cycle, CDKs and cancer: a changing paradigm [My Copy] Nat Rev Cancer, Vol. 9, No. 3. (March 2009), pp. 153-166. by Marcos Malumbres, Mariano Barbacid posted to cancer cdk cell-cycle by guhjy on 2009-07-10 14:50:58 as along with 3 people twinkling misonneh catcremona
	Discovery of Aminothiazole Inhibitors of Cyclin-Dependent Kinase 2: Synthesis, X-ray Crystallographic Analysis, and Biological Activities [My Copy] Journal of Medicinal Chemistry, Vol. 45, No. 18. (1 August 2002), pp. 3905-3927. by Kyoung S. Kim, S. David Kimball, Raj N. Misra, et al.David B. Rawlins, John T. Hunt, Hai-Yun Xiao, Songfeng Lu, Ligang Qian, Wen-Ching Han, Weifang Shan, Toomas Mitt, Zhen-Wei Cai, Michael A. Poss, Hong Zhu, John S. Sack, John S. Tokarski, Chieh Y. Chang, Nikola Pavletich, Amrita Kamath, William G. Humphreys, Punit Marathe, Isia Bursuker, Kristen A. Kellar, Urvashi Roongta, Roberta Batorsky, Janet G. Mulheron, David Bol, Craig R. Fairchild, Francis Y. Lee, Kevin R. Webster posted to cdk by references on 2009-07-02 08:57:35 as
	Imidazole piperazines: SAR and development of a potent class of cyclin-dependent kinase inhibitors with a novel binding mode [My Copy] Bioorganic & Medicinal Chemistry Letters, Vol. 18, No. 15. (01 August 2008), pp. 4442-4446. by Finlay, David G. Acton, David M. Andrews, et al.Andrew J. Barker, Michael Dennis, Eric Fisher, Mark A. Graham, Clive P. Green, David W. Heaton, Galith Karoutchi posted to cdk by references on 2009-07-02 08:48:28 as
	CDK Inhibitors: Cell Cycle Regulators and Beyond [My Copy] Vol. 14, No. 2. (12 February 2008), pp. 159-169. by Arnaud Besson, Steven F. Dowdy, James M. Roberts posted to cdk by references on 2009-07-01 08:36:23 as
	CDK inhibitors in cancer therapy: what is next? [My Copy] Trends in Pharmacological Sciences, Vol. 29, No. 1. (January 2008), pp. 16-21. by M. Malumbres, P. Pevarello, M. Barbacid, J. Bischoff posted to cdk by references on 2009-06-30 07:27:00 as along with 1 person catcremona
	Progress in the evaluation of CDK inhibitors as anti-tumor agents [My Copy] Drug Discovery Today, Vol. 13, No. 19-20. (October 2008), pp. 875-881. by C. Mcinnes posted to cdk by references on 2009-06-30 07:22:02 as
	Inhibitors in control Cyclin Dependent Kinase (CDK) Inhibitors (Curr. Top. Microbiol. Immunol. 227) edited by P. K. Vogt and S. I. Reed [My Copy] Trends in Cell Biology, Vol. 9, No. 3. (1 March 1999), 122. by A. Trumpp posted to cdk by references on 2009-06-30 07:19:27 as
	Phosphorylation of Retinoblastoma Protein by Viral Protein with Cyclin-Dependent Kinase Function [My Copy] Science, Vol. 320, No. 5877. (9 May 2008), pp. 797-799. by Adam J. Hume, Jonathan S. Finkel, Jeremy P. Kamil, Donald M. Coen, Michael R. Culbertson, Robert F. Kalejta posted to cdk retinoblastoma by feltesm on 2009-06-16 03:21:36 as along with 4 people biomcgary neils mclarenv Petersarkies
	Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex [My Copy] Nature, Vol. 376, No. 6538. (27 July 1995), pp. 313-320. by Philip D. Jeffrey, Alicia Russo, A., et al.Kornelia Polyak, Emma Gibbs, Jerard Hurwitz, Joan Massague, Nikola Pavletich, P. posted to cdk by ubcg08l on 2009-05-12 12:51:05 as along with 3 people catcremona helenc karunesh
	The Chemistry Development Kit (CDK): An Open-Source Java Library for Chemo- and Bioinformatics. [My Copy] ChemInform, Vol. 34, No. 21. (2003) by Christoph Steinbeck, Yongquan Han, Stefan Kuhn, Oliver Horlacher, Edgar Luttmann, Egon Willighagen posted to bioinformatics cdk cheminformatics christoph-steinbeck egon-willighagen java by dullhunk on 2009-04-20 16:10:09 as along with 1 person Scis0000002
	ChEMBL. An interview with John Overington, team leader, chemogenomics at the European Bioinformatics Institute Outstation of the European Molecular Biology Laboratory (EMBL-EBI) [My Copy] Journal of Computer-Aided Molecular Design, Vol. 23, No. 4. (1 April 2009), pp. 195-198. by Wendy Warr posted to cdk chemical database ebi interview by zimbo1 on 2009-03-10 10:48:48 as along with 1 person dullhunk
	Cyclin-dependent kinase pathways as targets for cancer treatment. [My Copy] Journal of clinical oncology : official journal of the American Society of Clinical Oncology, Vol. 24, No. 11. (10 April 2006), pp. 1770-1783. by G. I. Shapiro posted to cancer cdk inhibitors review treatment by catcremona on 2009-02-25 22:52:56 as
	CDK-dependent phosphorylation of BRCA2 as a regulatory mechanism for recombinational repair [My Copy] Nature, Vol. 434, No. 7033. (31 March 2005), pp. 598-604. by Fumiko Esashi, Nicole Christ, Julian Gannon, et al.Yilun Liu, Tim Hunt, Maria Jasin, Stephen C. West posted to brca2 cdk dna repair by catcremona on 2009-02-25 22:45:22 as
	CDK targets Sae2 to control DNA-end resection and homologous recombination [My Copy] Nature (20 August 2008) by Pablo Huertas, Felipe Cortés-Ledesma, Alessandro A. Sartori, Andrés Aguilera, Stephen P. Jackson posted to cdk dna homologous recombination repair by catcremona on 2009-02-25 22:43:55 as along with 1 person sandersl
	Proliferating cell nuclear antigen and p21 are components of multiple cell cycle kinase complexes. [My Copy] Molecular biology of the cell, Vol. 4, No. 9. (September 1993), pp. 897-906. by H. Zhang, Y. Xiong, D. Beach posted to cdk p21 pcna by catcremona on 2009-02-24 18:17:43 as
	The APC/C inhibitor, Emi1, is essential for prevention of rereplication. [My Copy] Genes & development, Vol. 21, No. 2. (15 January 2007), pp. 184-194. by Y. J. Machida, A. Dutta posted to apc cdk rereplication by catcremona on 2009-02-17 10:28:14 as
	Cell cycle arrest and DNA endoreduplication following p21Waf1/Cip1 expression. [My Copy] Oncogene, Vol. 17, No. 13. (1 October 1998), pp. 1691-1703. by S. Bates, K. M. Ryan, A. C. Phillips, K. H. Vousden posted to cdk dna inhibition p21 replication rereplication by catcremona on 2009-02-17 08:55:58 as
	Cyclin A-dependent kinase activity affects chromatin binding of ORC, Cdc6, and MCM in egg extracts of Xenopus laevis. [My Copy] European journal of biochemistry / FEBS, Vol. 264, No. 2. (September 1999), pp. 415-426. by M. Findeisen, M. El-Denary, T. Kapitza, R. Graf, U. Strausfeld posted to cdc6 cdk cyclina dna mcm orc replication by catcremona on 2009-02-17 08:40:39 as
	Human geminin promotes pre-RC formation and DNA replication by stabilizing CDT1 in mitosis. [My Copy] The EMBO journal, Vol. 23, No. 15. (4 August 2004), pp. 3122-3132. by A. Ballabeni, M. Melixetian, R. Zamponi, L. Masiero, F. Marinoni, K. Helin posted to activity cdk cdt1 dna geminin replication by catcremona on 2009-02-16 23:35:25 as
	S-phase-promoting cyclin-dependent kinases prevent re-replication by inhibiting the transition of replication origins to a pre-replicative state. [My Copy] Curr Biol, Vol. 5, No. 11. (1 November 1995), pp. 1257-1269. by C. Dahmann, J. F. Diffley, K. A. Nasmyth posted to activity cdk dna initiation replication sphase by catcremona on 2009-02-16 23:23:13 as along with 1 person sansamcl
	Assembly of a complex containing Cdc45p, replication protein A, and Mcm2p at replication origins controlled by S-phase cyclin-dependent kinases and Cdc7p-Dbf4p kinase. [My Copy] Molecular and cellular biology, Vol. 20, No. 9. (May 2000), pp. 3086-3096. by L. Zou, B. Stillman posted to cdc45 cdc7 cdk dna initiation mcm replication rpa by catcremona on 2009-02-16 23:21:11 as along with 1 person bmduggan
	Distinct Action of the Retinoblastoma Pathway on the DNA Replication Machinery Defines Specific Roles for Cyclin-Dependent Kinase Complexes in Prereplication Complex Assembly and S-Phase Progression [My Copy] Mol. Cell. Biol., Vol. 26, No. 20. (15 October 2006), pp. 7667-7681. by Wesley A. Braden, Jon M. Lenihan, Zhengdao Lan, et al.Scott K. Luce, William Zagorski, Emily Bosco, Michael F. Reed, Jeanette G. Cook, Erik S. Knudsen posted to cdk dna rb replication by catcremona on 2009-02-16 22:45:16 as
	Identification of Mcm2 phosphorylation sites by S-phase-regulating kinases. [My Copy] The Journal of biological chemistry, Vol. 281, No. 15. (14 April 2006), pp. 10281-10290. by A. Montagnoli, B. Valsasina, D. Brotherton, et al.S. Troiani, S. Rainoldi, P. Tenca, A. Molinari, C. Santocanale posted to cdk mcm phosphorylation by catcremona on 2009-02-16 22:41:05 as
	CDK Phosphorylation of a Novel NLS-NES Module Distributed between Two Subunits of the Mcm2-7 Complex Prevents Chromosomal Rereplication [My Copy] Mol. Biol. Cell, Vol. 16, No. 10. (1 October 2005), pp. 5026-5039. by Muluye E. Liku, Van Q. Nguyen, Audrey W. Rosales, Kaoru Irie, Joachim J. Li posted to cdk localization mcm nuclear phosphorylation by catcremona on 2009-02-16 22:39:04 as
	Cdt1 phosphorylation by cyclin A-dependent kinases negatively regulates its function without affecting geminin binding. [My Copy] J Biol Chem, Vol. 279, No. 19. (7 May 2004), pp. 19691-19697. by N. Sugimoto, Y. Tatsumi, T. Tsurumi, et al.A. Matsukage, T. Kiyono, H. Nishitani, M. Fujita posted to cdk cdt1 cyclina geminin phosphorylation by catcremona on 2009-02-16 22:33:44 as along with 1 person DNAReplication
	Interplay between S-cyclin-dependent kinase and Dbf4-dependent kinase in controlling DNA replication through phosphorylation of yeast Mcm4 N-terminal domain. [My Copy] Molecular biology of the cell, Vol. 19, No. 5. (May 2008), pp. 2267-2277. by A. Devault, E. Gueydon, E. Schwob posted to cdk dna mcm phosphorylation replication by catcremona on 2009-02-16 22:13:41 as
	Transcription networks and cyclin/CDKs: the yin and yang of cell cycle oscillators. [My Copy] Cell cycle (Georgetown, Tex.), Vol. 7, No. 17. (1 September 2008), pp. 2626-2629. by Laura A. Simmons Kovacs, David A. Orlando, Steven B. Haase posted to cdk cell-cycle cyclin by guhjy on 2009-02-08 03:26:27 as
	Expanding role of cyclin dependent kinases in cytokine inducible gene expression. [My Copy] Cell cycle (Georgetown, Tex.), Vol. 7, No. 17. (September 2008), pp. 2661-2666. by A. R. Brasier posted to cdk cytokine by guhjy on 2009-02-08 03:26:16 as
	Cdk phosphorylation triggers sequential intramolecular interactions that progressively block Rb functions as cells move through G1. [My Copy] Cell, Vol. 98, No. 6. (17 September 1999), pp. 859-869. by J. W. Harbour, R. X. Luo, A. Dei Santi, A. A. Postigo, D. C. Dean posted to cdk phosphorylation rb by catcremona on 2009-02-05 18:29:26 as
	Dual mechanisms for the inhibition of E2F binding to RB by cyclin- dependent kinase-mediated RB phosphorylation [My Copy] Mol. Cell. Biol., Vol. 17, No. 10. (1 October 1997), pp. 5771-5783. by E. S. Knudsen, J. Y. Wang posted to cdk e2f phosphorylation rb by catcremona on 2009-02-05 18:14:59 as
	CP110, a cell cycle-dependent CDK substrate, regulates centrosome duplication in human cells. [My Copy] Developmental cell, Vol. 3, No. 3. (September 2002), pp. 339-350. by Z. Chen, V. B. Indjeian, M. McManus, L. Wang, B. D. Dynlacht posted to cdk centrosome cp110 target by catcremona on 2009-02-05 00:06:47 as
	Functional inactivation of the retinoblastoma protein requires sequential modification by at least two distinct cyclin-cdk complexes. [My Copy] Molecular and cellular biology, Vol. 18, No. 2. (February 1998), pp. 753-761. by A. S. Lundberg, R. A. Weinberg posted to cdk cyclin rb by catcremona on 2009-02-04 23:20:55 as
	The many phases of anaphase. [My Copy] Trends in biochemical sciences, Vol. 30, No. 10. (October 2005), pp. 559-568. by A. de Gramont, O. Cohen-Fix posted to activity anaphase cdk mitosis review by catcremona on 2009-02-04 01:55:53 as
	Deregulated expression of E2F-1 induces cyclin A- and E-associated kinase activities independently from cell cycle position. [My Copy] Oncogene, Vol. 14, No. 19. (15 May 1997), pp. 2251-2257. by T. Soucek, O. Pusch, E. Hengstschläger-Ottnad, P. D. Adams, M. Hengstschläger posted to cdk cyclina cycline e2f by catcremona on 2009-02-01 23:00:40 as
	Cyclin-dependent kinase activation and S-phase induction of the cyclin B1 gene are linked through the CCAAT elements. [My Copy] Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, Vol. 8, No. 7. (July 1997), pp. 811-820. by K. S. Katula, K. L. Wright, H. Paul, et al.D. R. Surman, F. J. Nuckolls, J. W. Smith, J. P. Ting, J. Yates, J. P. Cogswell posted to cbp ccaat cdk cyclinb by catcremona on 2009-02-01 22:26:35 as
	Activation of human cyclin-dependent kinases in vitro. [My Copy] Molecular biology of the cell, Vol. 3, No. 5. (May 1992), pp. 571-582. by D. Desai, Y. Gu, D. O. Morgan posted to activation binding cdk cyclin by catcremona on 2009-02-01 19:18:51 as
	Protein kinase regulation: insights from crystal structure analysis. [My Copy] Current opinion in cell biology, Vol. 6, No. 2. (April 1994), pp. 239-246. by D. O. Morgan, H. L. De Bondt posted to cdk review structure by catcremona on 2009-02-01 16:45:25 as

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cyclin	26
review	26
dna	18
inhibitor	17
phosphorylation	17
replication	13
cancer	12
cdk2	11
cell	11
kinase	11
cdk1	10
cellcycle	10
cdki	9
cell-cycle	9
cycle	9
inhibition	9
cdc2l5	8
p21	8
p27	8
rereplication	8
cyclina	7
e2f	7
rb	7
ctd	6
mcm	6
splicing	6
transcription	6
cdc2	5
oncogene	5
paper	5
regulation	5
activation	4
binding	4
cak	4
cdk7	4
cdk8	4
development	4
rnapii	4
roscovitine	4
structure	4
activity	3
cdk9	3
cdt1	3
cyclind	3
geminin	3
initiation	3
p16	3
pcna	3
protein	3
repair	3
sea	3
target	3
tyrosine	3
urchin	3
5	2
apc	2
cdc2-related	2
cdc25	2
cdc6	2
cdk-like	2
cdk13	2
cdk6	2
centrosome	2
cks	2
comparative	2
critical	2
crkrs	2
ctd-cdk	2
ctd-kinase	2
cycd	2
cycl	2
cycline	2
cyclinl	2
d1b	2
early	2
endoreduplication	2
exotic	2
frog	2
mammalian	2
meiose	2
microrna	2
mir-449	2
mitosis	2
morphogenesis	2
motif	2
novel	2
open-bio	2
p32	2
pharmacology	2
pre-mrna	2
screening	2
spermatogenesis	2
splice	2
sr	2
subfamily	2
synthesis	2
transcrption	2
variant	2
vertebrate	2
yeast	2

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