Tag dhfr [104 articles] Export

Recent papers classified by the tag dhfr.

	Correlated motion and the effect of distal mutations in dihydrofolate reductase. [My Copy] Proc Natl Acad Sci U S A, Vol. 100, No. 12. (10 June 2003), pp. 6980-6985. by T. H. Rod, J. L. Radkiewicz, C. L. Brooks posted to md dhfr catalysis by paulymer on 2009-12-04 05:29:51 as along with 1 person ruvido
	Impact of distal mutations on the network of coupled motions correlated to hydride transfer in dihydrofolate reductase. [My Copy] Proc Natl Acad Sci U S A, Vol. 102, No. 19. (10 May 2005), pp. 6807-6812. by K. F. Wong, T. Selzer, S. J. Benkovic, S. Hammes-Schiffer posted to md dhfr catalysis by paulymer on 2009-12-04 05:29:06 as along with 1 person ruvido
	A lentivirus-mediated genetic screen identifies dihydrofolate reductase (DHFR) as a modulator of beta-catenin/GSK3 signaling. [My Copy] PloS one, Vol. 4, No. 9. (2009) by Richard A. Klinghoffer, Jason Frazier, James Annis, et al.Jason D. Berndt, Brian S. Roberts, William T. Arthur, Raul Lacson, Xiaohua Douglas D. Zhang, Marc Ferrer, Randall T. Moon, Michele A. Cleary posted to pbmc mtx gsk3 dhfr catenin by guhjy on 2009-09-06 10:08:05 as
	IGF-I alleviates diabetes-induced RhoA activation, eNOS uncoupling, and myocardial dysfunction. [My Copy] American journal of physiology. Regulatory, integrative and comparative physiology, Vol. 294, No. 3. (March 2008) by Jun Ren, Jinhong Duan, D. Paul Thomas, et al.Xiaoping Yang, Nair Sreejayan, James R. Sowers, Annarosa Leri, Jan Kajstura, Feng Gao, Piero Anversa posted to uncoupling ros rho mouse igf enos dm dhfr bh4 by guhjy on 2009-08-28 16:06:57 as
	Regulation of tetrahydrobiopterin synthesis and bioavailability in endothelial cells. [My Copy] Cell biochemistry and biophysics, Vol. 41, No. 3. (2004), pp. 415-434. by Wenjuan Shi, Cynthia J. Meininger, Tony E. Haynes, Kazuyuki Hatakeyama, Guoyao Wu posted to tnf tgfb ros insulin il1 gtpch folate estrogen endothelium dhfr bh4 arginine by guhjy on 2009-08-27 10:09:16 as
	Pravastatin enhances beneficial effects of olmesartan on vascular injury of salt-sensitive hypertensive rats, via pleiotropic effects. [My Copy] Arteriosclerosis, thrombosis, and vascular biology, Vol. 27, No. 3. (March 2007), pp. 556-563. by Eiichiro Yamamoto, Takuro Yamashita, Tomoko Tanaka, et al.Keiichiro Kataoka, Yoshiko Tokutomi, Zhong-Fang F. Lai, Yi-Fei F. Dong, Shinji Matsuba, Hisao Ogawa, Shokei Kim-Mitsuyama posted to statin rat enos dhfr arb akt by guhjy on 2009-08-27 10:00:39 as
	Effects of folate cycle disruption by the green tea polyphenol epigallocatechin-3-gallate [My Copy] The International Journal of Biochemistry & Cell Biology, Vol. 39, No. 12. (2007), pp. 2215-2225. by Enma Navarro-Perán, Juan Cabezas-Herrera, Luis S. Campo, José N. Rodríguez-López posted to tea dhfr by guhjy on 2009-08-27 07:42:42 as
	Heat shock protein 72 binds and protects dihydrofolate reductase against oxidative injury [My Copy] Biochemical and Biophysical Research Communications, Vol. 313, No. 1. (02 January 2004), pp. 185-192. by Mark W. Musch, Aditya Kapil, Eugene B. Chang posted to hsp dhfr by guhjy on 2009-08-27 07:39:57 as
	AT1-receptor blockade by telmisartan upregulates GTP-cyclohydrolase I and protects eNOS in diabetic rats [My Copy] Free Radical Biology and Medicine, Vol. 45, No. 5. (01 September 2008), pp. 619-626. by Philip Wenzel, Eberhard Schulz, Matthias Oelze, et al.Johanna Müller, Swenja Schuhmacher, Mohamed S. S. Alhamdani, Johannes Debrezion, Marcus Hortmann, Kurt Reifenberg, Ingrid Fleming posted to gtpch rat no enos dm dhfr arb by guhjy on 2009-08-27 05:52:34 as
	Mechanisms underlying recoupling of eNOS by HMG-CoA reductase inhibition in a rat model of streptozotocin-induced diabetes mellitus. [My Copy] Atherosclerosis, Vol. 198, No. 1. (May 2008), pp. 65-76. by Philip Wenzel, Andreas Daiber, Matthias Oelze, et al.Moritz Brandt, Ellen Closs, Jian Xu, Thomas Thum, Johann Bauersachs, Georg Ertl, Ming-Hui H. Zou, Ulrich Förstermann, Thomas Münzel posted to uncoupling stz statin no gtpch enos dm dhfr by guhjy on 2009-08-27 05:40:01 as
	Identification of a cis-acting element of human dihydrofolate reductase mRNA [My Copy] Biochemical and Biophysical Research Communications, Vol. 369, No. 3. (09 May 2008), pp. 795-800. by N. Tai, J. Schmitz, T. Chen, M. Oneill, E. Chu posted to dhfr by guhjy on 2009-08-27 05:32:52 as
	Regulation of human dihydrofolate reductase activity and expression. [My Copy] Vitamins and hormones, Vol. 79 (2008), pp. 267-292. by Emine Ercikan E. Abali, Nancy E. Skacel, Hilal Celikkaya, Yi-Ching C. Hsieh posted to dhfr by guhjy on 2009-08-27 05:32:10 as
	Dihydrofolate reductase inhibitors as antibacterial agents. [My Copy] Biochemical pharmacology, Vol. 71, No. 7. (30 March 2006), pp. 941-948. by Stephen Hawser, Sergio Lociuro, Khalid Islam posted to inhibitor dhfr by guhjy on 2009-08-27 05:10:12 as
	Tetrahydrobiopterin, superoxide, and vascular dysfunction [My Copy] Free Radical Biology and Medicine (21 July 2009) by Jeannette Vásquez-Vivar posted to ros nos no dhfr cv bh4 by guhjy on 2009-08-26 17:18:13 as
	Attenuation of angiotensin II signaling recouples eNOS and inhibits nonendothelial NOX activity in diabetic mice. [My Copy] Diabetes, Vol. 56, No. 1. (January 2007), pp. 118-126. by Jeong-Ho H. Oak, Hua Cai posted to uncoupling stz nox no mouse enos dm dhfr bh4 arb aii acei by guhjy on 2009-08-26 16:56:45 as
	Quantitative regulation of intracellular endothelial nitric-oxide synthase (eNOS) coupling by both tetrahydrobiopterin-eNOS stoichiometry and biopterin redox status: insights from cells with tet-regulated GTP cyclohydrolase I expression. [My Copy] The Journal of biological chemistry, Vol. 284, No. 2. (9 January 2009), pp. 1136-1144. by Mark J. Crabtree, Amy L. Tatham, Yasir Al-Wakeel, et al.Nicholas Warrick, Ashley B. Hale, Shijie Cai, Keith M. Channon, Nicholas J. Alp posted to no gtpch endothelium dhfr bh4 by guhjy on 2009-08-26 16:56:00 as
	Critical role for tetrahydrobiopterin recycling by dihydrofolate reductase in regulation of endothelial nitric oxide synthase coupling: Relative importance of the de Novo Biopterin synthesis vs. salvage pathways. [My Copy] The Journal of biological chemistry (7 August 2009) by Mark J. Crabtree, Amy L. Tatham, Ashley B. Hale, Nicholas J. Alp, Keith M. Channon posted to no gtpch endothelium dhfr bh4 by guhjy on 2009-08-26 16:54:44 as
	Tetrahydrobiopterin recycling, a key determinant of endothelial nitric-oxide synthase-dependent signaling pathways in cultured vascular endothelial cells. [My Copy] The Journal of biological chemistry, Vol. 284, No. 19. (8 May 2009), pp. 12691-12700. by Toru Sugiyama, Bruce D. Levy, Thomas Michel posted to no gtpch endothelium dhfr bh4 by guhjy on 2009-08-26 16:53:28 as
	Endothelial dihydrofolate reductase: critical for nitric oxide bioavailability and role in angiotensin II uncoupling of endothelial nitric oxide synthase. [My Copy] Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, No. 25. (21 June 2005), pp. 9056-9061. by Karel Chalupsky, Hua Cai posted to uncoupling ros nox no enos endothelium dhfr bh4 aii by guhjy on 2009-08-26 16:51:28 as
	Mechanistic insights into folic acid-dependent vascular protection: Dihydrofolate reductase-mediated reduction in oxidant stress in endothelial cells and angiotensin II-infused mice: A novel HPLC-based fluorescent assay for DHFR activity. [My Copy] Journal of molecular and cellular cardiology (3 August 2009) by Ling Gao, Karel Chalupsky, Enrico Stefani, Hua Cai posted to ros method folate dhfr aii by guhjy on 2009-08-26 16:45:22 as
	Role of angiotensin II on dihydrofolate reductase, GTP-cyclohydrolase 1 and nitric oxide synthase expressions in renal ischemia-reperfusion. [My Copy] American journal of nephrology, Vol. 28, No. 4. (2008), pp. 692-700. by Yuyen Seujange, Somchit Eiam-Ong, Thaweesak Tirawatnapong, Somchai Eiam-Ong posted to gtpch no kidney dhfr aki aii by guhjy on 2009-08-26 16:43:43 as
	miR-192 Regulates dihydrofolate reductase and cellular proliferation through the p53-microRNA circuit. [My Copy] Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 14, No. 24. (15 December 2008), pp. 8080-8086. by Bo Song, Yuan Wang, Kenji Kudo, Elaine J. Gavin, Yaguang Xi, Jingfang Ju posted to proliferation p53 p21 mirna192 mirna dhfr by guhjy on 2009-07-11 16:08:40 as along with 1 person and 1 group jfr microRNA
	Repression of the human dihydrofolate reductase gene by a non-coding interfering transcript [My Copy] Nature (21 January 2007) by Igor Martianov, Aroul Ramadass, Ana S. Barros, Natalie Chow, Alexandre Akoulitchev posted to dhfr ncrna by galka8_diploma on 2009-06-29 12:48:22 as along with 4 people and 2 groups aprasad maximilianh alexg dchughes G4ID Genetics-of-Gambling
	GroEL-mediated folding of structurally homologous dihydrofolate reductases [My Copy] Journal of Molecular Biology, Vol. 268, No. 2. (02 May 1997), pp. 512-525. by Clay A. Clark, Carl Frieden posted to dhfr folding folding-intermediates groel-substrate by rph on 2009-05-27 18:58:55 as
	Analysis of the haemolysin transport process through the secretion from Escherichia coli of PCM, CAT or beta-galactosidase fused to the Hly C-terminal signal domain. [My Copy] Molecular microbiology, Vol. 5, No. 10. (October 1991), pp. 2557-2568. by B. Kenny, R. Haigh, I. B. Holland posted to dhfr fusion hemolysin hlyb type-i by martainn on 2009-04-23 17:09:21 as
	Secretion of genetically-engineered dihydrofolate reductase from Escherichia coli using an E. coli alpha-hemolysin membrane translocation system. [My Copy] Applied microbiology and biotechnology, Vol. 37, No. 6. (September 1992), pp. 765-771. by H. Nakano, Y. Kawakami, H. Nishimura posted to 4grant dhfr hemolysin hlyb mtx type-i by martainn on 2009-04-23 17:07:45 as
	Yop fusions to tightly folded protein domains and their effects on Yersinia enterocolitica type III secretion. [My Copy] Journal of bacteriology, Vol. 184, No. 13. (July 2002), pp. 3740-3745. by V. T. Lee, O. Schneewind posted to 4grant dhfr mtx type-iii yersinia by martainn on 2009-04-23 17:03:27 as
	Yersinia enterocolitica type III secretion: evidence for the ability to transport proteins that are folded prior to secretion. [My Copy] BMC microbiology, Vol. 4 (12 July 2004) by G. Wilharm, V. Lehmann, W. Neumayer, J. Trcek, J. Heesemann posted to dhfr fusion mtx type-iii by martainn on 2009-04-23 17:00:34 as
	Resistance to methotrexate due to AcrAB-dependent export from Escherichia coli. [My Copy] Antimicrobial agents and chemotherapy, Vol. 44, No. 11. (November 2000), pp. 3210-3212. by S. J. Kopytek, J. C. Dyer, G. S. Knapp, J. C. Hu posted to 4grant dhfr fusion mtx tolc by martainn on 2009-04-23 16:58:31 as
	A Novel In Silico Approach to Drug Discovery via Computational Intelligence [My Copy] Journal of Chemical Information and Modeling, Vol. 0, No. 0. (0000) by David Hecht, Gary B. Fogel posted to affinities binding calculated dhfr diversity docking space synthetically unfeasible by zimbo1 on 2009-04-16 07:58:26 as along with 3 people Scis0000002 sschurer middledomain
	Dynamic Dysfunction in Dihydrofolate Reductase Results from Antifolate Drug Binding: Modulation of Dynamics within a Structural State [My Copy] Structure, Vol. 17, No. 3. (11 March 2009), pp. 386-394. by Randall V. Mauldin, Mary J. Carroll, Andrew L. Lee posted to dhfr enzyme-inhibition by ae1054 on 2009-03-29 11:16:36 as along with 1 person and 2 groups barry structural_bioinformatics McCammon
	Expression and site-directed mutagenesis of human dihydrofolate reductase [My Copy] Biochemistry, Vol. 27, No. 10. (1 May 1988), pp. 3664-3671. by Neal J. Prendergast, Tavner J. Delcamp, Philip L. Smith, James H. Freisheim posted to dhfr hdhfr by rph on 2009-03-06 18:23:27 as
	Crystal structures of recombinant human dihydrofolate reductase complexed with folate and 5-deazafolate [My Copy] Biochemistry, Vol. 29, No. 40. (1 October 1990), pp. 9467-9479. by Jay F. Davies, Tavner J. Delcamp, Neal J. Prendergast, Victor A. Ashford, James H. Freisheim, Joseph Kraut posted to dhfr hdhfr by rph on 2009-03-06 18:20:59 as
	Crystal structure of human dihydrofolate reductase complexed with folate [My Copy] European Journal of Biochemistry, Vol. 174, No. 2. (1988), pp. 377-385. by Christian Oefner, Allan D'Arcy, Fritz K. Winkler posted to dhfr hdhfr by rph on 2009-03-06 18:18:56 as
	Protein Dynamics in Enzymatic Catalysis: Exploration of Dihydrofolate Reductase [My Copy] Journal of the American Chemical Society, Vol. 122, No. 2. (1 January 2000), pp. 225-231. by Jennifer L. Radkiewicz, Charles L. Brooks posted to dhfr molecular-dynamics by bmduggan on 2009-03-05 04:02:42 as
	Conditions of Forming Protein Complexes with GroEL Can Influence the Mechanism of Chaperonin-assisted Refolding [My Copy] J. Biol. Chem., Vol. 272, No. 1. (3 January 1997), pp. 32-35. by Boris M. Gorovits, Paul M. Horowitz posted to dhfr groel by rph on 2008-12-15 19:47:30 as
	Determination of Regions in the Dihydrofolate Reductase Structure That Interact with the Molecular Chaperonin GroEL† [My Copy] Biochemistry, Vol. 35, No. 18. (1 January 1996), pp. 5893-5901. by Clay A. Clark, Eric Hugo, Carl Frieden posted to chaperonin dhfr groel by rph on 2008-12-12 19:30:50 as
	Chaperonin-mediated protein folding at the surface of groEL through a 'molten globule'-like intermediate [My Copy] Nature, Vol. 352, No. 6330. (4 July 1991), pp. 36-42. by Jorg Martin, Thomas Langer, Raina Boteva, Andrea Schramel, Arthur L. Horwich, Hartl posted to dhfr folding groel by rph on 2008-12-11 18:49:15 as
	A polypeptide bound by the chaperonin groEL is localized within a central cavity [My Copy] Proceedings of the National Academy of Sciences of the United States of America, Vol. 90, No. 9. (1 May 1993), pp. 3978-3982. by K. Braig, M. Simon, F. Furuya, J. F. Hainfeld, A. L. Horwich posted to dhfr folding groel by rph on 2008-12-11 18:43:20 as
	Different conformations for the same polypeptide bound to chaperones DnaK and GroEL [My Copy] Nature, Vol. 355, No. 6359. (30 January 1992), pp. 455-457. by Samuel J. Landry, Robert Jordan, Roger Mcmacken, Lila M. Gierasch posted to dhfr groel by rph on 2008-12-06 02:52:03 as
	Complex interactions between the chaperonin 60 molecular chaperone and dihydrofolate reductase [My Copy] Biochemistry, Vol. 30, No. 40. (1 October 1991), pp. 9716-9723. by Paul V. Viitanen, Gail K. Donaldson, George H. Lorimer, Thomas H. Lubben, Anthony A. Gatenby posted to dhfr groel by rph on 2008-12-06 02:45:39 as
	Significant hydrogen exchange protection in GroEL-bound DHFR is maintained during iterative rounds of substrate cycling [My Copy] Protein Sci, Vol. 5, No. 12. (1 December 1996), pp. 2506-2513. by M. Groszlig, C. V. Robinson, M. Mayhew, F. U. Hartl, S. E. Radford posted to dhfr exchange groel by rph on 2008-12-05 18:00:33 as
	Ligand Binding and Circular Permutation Modify Residue Interaction Network in DHFR [My Copy] PLoS Comput Biol, Vol. 3, No. 6. (15 June 2007), e117. by Zengjian Hu, Donnell Bowen, William M. Southerland, et al. Del, Yongping Pan, Ruth Nussinov, Buyong Ma posted to analysis dhfr interaction network protein structure by neils on 2008-09-17 07:33:17 as
	Protein flexibility and species specificity in structure-based drug discovery: dihydrofolate reductase as a test system. [My Copy] Journal of the American Chemical Society, Vol. 129, No. 12. (28 March 2007), pp. 3634-3640. by A. L. Bowman, M. G. Lerner, H. A. Carlson posted to 2007 dhfr flexibility by higueruelo on 2008-07-07 11:54:33 as
	Diagnostic chemical shift markers for loop conformation and substrate and cofactor binding in dihydrofolate reductase complexes. [My Copy] Protein Sci, Vol. 12, No. 10. (October 2003), pp. 2230-2238. by M. J. Osborne, R. P. Venkitakrishnan, H. J. Dyson, P. E. Wright posted to dhfr by lna on 2008-06-27 15:33:28 as along with 1 person dgruiz
	Cell-free translation reconstituted with purified components. [My Copy] Nature biotechnology, Vol. 19, No. 8. (August 2001), pp. 751-755. by Y. Shimizu, A. Inoue, Y. Tomari, et al.T. Suzuki, T. Yokogawa, K. Nishikawa, T. Ueda posted to dhfr by lna on 2008-06-27 15:23:30 as
	Letter to the Editor: NMR-based solution structure of the complex of Lactobacillus casei dihydrofolate reductase with trimethoprim and NADPH [My Copy] Journal of Biomolecular NMR, Vol. 24, No. 1. (2002), pp. 67-70. by Vladimir I. Polshakov, Eugeni G. Smirnov, Berry Birdsall, Geoff Kelly, James Feeney posted to assignments dhfr by rph on 2008-05-15 03:45:26 as
	Letter to the Editor: Backbone HN, N, Cα, C′ and Cβ assignments of the 19 kDa DHFR/NADPH complex at 9 °C and pH 7.6 [My Copy] Journal of Biomolecular NMR, Vol. 16, No. 4. (1 April 2000), pp. 349-350. by Eduardo Zaborowski, John Chung, Gerard Kroon, Jane H. Dyson, Peter E. Wright posted to assignments dhfr by rph on 2008-05-13 01:28:17 as
	Detection of Long-lived Bound Water Molecules in Complexes of Human Dihydrofolate Reductase with Methotrexate and NADPH [My Copy] Journal of Molecular Biology, Vol. 247, No. 2. (24 March 1995), pp. 294-308. by Elizabeth M. Meiering, Gerhard Wagner posted to bulk-magnetization dhfr hdhfr hydration by rph on 2008-05-01 01:41:04 as
	NMR solution structure of the antitumor compound PT523 and NADPH in the ternary complex with human dihydrofolate reductase. [My Copy] Biochemistry, Vol. 36, No. 15. (15 April 1997), pp. 4399-4411. by J. M. Johnson, E. M. Meiering, J. E. Wright, J. Pardo, A. Rosowsky, G. Wagner posted to dhfr hdhfr nmr structure by rph on 2008-05-01 01:38:26 as

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inhibitors	13
pcarinii	11
stucture	10
no	9
bh4	8
catalysis	7
groel	7
gtpch	7
mtx	7
plasmodium	7
binding	6
enos	6
examples	6
human	6
modelling	6
endothelium	5
enzyme	5
hdhfr	5
ros	5
aii	4
calbicans	4
chemistry	4
dm	4
ligands	4
md	4
selectivity	4
uncoupling	4
4grant	3
allostery	3
arb	3
folding	3
fusion	3
kinetics	3
motion	3
mutations	3
protein	3
rat	3
simulation	3
structure	3
struktur	3
stz	3
vibrational_modes	3
assignments	2
docking	2
folate	2
hemolysin	2
hlyb	2
mouse	2
nmr	2
nox	2
specificity	2
statin	2
type-i	2
type-iii	2
2007	1
3dqsar	1
acei	1
affinities	1
akt	1
analysis	1
calculated	1
charmm	1
cv	1
dhfr-ts	1
dn	1
energy_landscape	1
enzyme-inhibition	1
exchange	1
flexibility	1
free-energy	1
groel-substrate	1
gsk3	1
hydration	1
il1	1
inhibitor	1
insulin	1
interaction	1
labelling	1
lysozyme	1
malaria	1
method	1
molecular-dynamics	1
nadph	1
ncrna	1
nfkb	1
normal_modes	1
open	1
p53	1
pbmc	1
relaxation_dispersion	1
resistance	1
smar	1
sp	1
synthetically	1
tea	1
tgfb	1
tolc	1
ts	1
unfeasible	1
yersinia	1

Tag dhfr [104 articles] Export

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